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8/24/13 1 An Overview of Anatomy PART 1 The Human Body: An Orientation • Anatomy • The study of the structure of the human body • Physiology • The study of body function PowerPoint® Lecture Presentations prepared by Leslie Hendon University of Alabama, Birmingham © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. An Overview of Anatomy An Overview of Anatomy • Subdisciplines of anatomy • Other branches of anatomy • Gross anatomy • Developmental anatomy • Regional anatomy • Embryology • Systemic anatomy • Pathological anatomy (pathology) • Surface anatomy • Radiographic anatomy • Microscopic anatomy (histology) • Functional morphology © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. An Overview of Anatomy The Hierarchy of Structural Organization • Anatomical terminology • Chemical level • Based on ancient Greek or Latin • Provides standard nomenclature worldwide • Atoms form molecules • Cellular level • Cells and their functional subunits • Tissue level • A group of cells performing a common function © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. 1 8/24/13 Figure 1.1 Recognizing connections between structural levels leads to better understanding of organismal function. The Hierarchy of Structural Organization • Organ level • A discrete structure made up of more than one tissue • Organ system level • Organs working together for a common purpose • Organismal level • The result of all simpler levels working in unison © 2014 Pearson Education, Inc. Integumentary System • Forms external body covering • Protects deeper tissues from injury • Synthesizes vitamin D • Site of cutaneous receptors • (pain, pressure, etc.) and sweat and oil glands Skeletal System • Protects and supports body organs • Provides a framework for muscles • Blood cells formed within bones • Stores minerals Muscular System • Allows manipulation of environment • Locomotion • Facial expression • Maintains posture • Produces heat © 2014 Pearson Education, Inc. Respiratory System • Keeps blood supplied with oxygen • Removes carbon dioxide • Gas exchange occurs through walls of air sacs in the lungs Digestive System • Breaks down food into absorbable units • Indigestible foodstuffs eliminated as feces Urinary System • Eliminates nitrogenous wastes • Regulates water, electrolyte, and acid-base balance Male & Female Reproductive Systems • • • • Overall function is to produce offspring Testes produce sperm and male sex hormones Ovaries produce eggs and female sex hormones Mammary glands produce milk © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Nervous System • Fast-acting control system • Responds to internal and external changes Endocrine System • Glands secrete hormones that regulate: • Growth • Reproduction • Nutrient use Cardiovascular System • Blood vessels transport blood • Heart pumps blood through blood vessels • Blood carries oxygen and carbon dioxide • It also carries nutrients and wastes Lymphatic System/Immunity • • • • Picks up fluid leaked from blood vessels Disposes of debris in the lymphatic system Houses white blood cells (lymphocytes) Mounts attack against foreign substances in the body © 2014 Pearson Education, Inc. Scale: Length, Volume, and Weight • System of measurement in anatomy is the metric system • Meter • Micrometer • Liter • Milliliter • Kilogram © 2014 Pearson Education, Inc. 2 8/24/13 Gross Anatomy—An Introduction Gross Anatomy—An Introduction • Regional and directional terms • Regional terms • Anatomical position—a common visual reference point • Person stands erect with feet together and eyes forward • Palms face anteriorly with the thumbs pointed away from the body © 2014 Pearson Education, Inc. • Axis of body – head, neck, and trunk • Appendicular region • Appendages • Standard directional terms • Are used by professionals to describe location of one body part in relation to another © 2014 Pearson Education, Inc. Figure 1.3a Anatomical position and regional terms. Figure 1.3b Anatomical position and regional terms. Axial region Cephalic (head) Frontal Orbital Nasal Oral Mental Cervical (neck) Thoracic Sternal Axillary Mammary Abdominal Umbilical Pelvic Inguinal (groin) Appendicular region Upper limb Acromial Brachial (arm) Antecubital Antebrachial (forearm) Carpal (wrist) Upper limb Acromial Brachial (arm) Olecranal Antebrachial (forearm) Manus (hand) Pollex Palmar Digital Manus (hand) Metacarpal Digital Lower limb Coxal (hip) Femoral (thigh) Patellar Crural (leg) Fibular or peroneal Pubic (genital) Pedal (foot) Tarsal (ankle) Metatarsal Digital Hallux Thorax Abdomen Back (Dorsum) © 2014 Pearson Education, Inc. • Axial region Anterior/Ventral Cephalic Otic Occipital (back of head) Cervical Back (dorsal) Scapular Vertebral Lumbar Sacral Gluteal Perineal (between anus and external genitalia) Lower limb Femoral (thigh) Popliteal Sural (calf) Fibular or peroneal Thorax Abdomen Back (Dorsum) Pedal (foot) Calcaneal Plantar © 2014 Pearson Education, Inc. Posterior/Dorsal Table 1.1 Orientation and Directional Terms (1 of 2) Regional and Directional Terms • Directional terms are used to explain precise location of body structure in relation to another body structure • Terms are paired with opposite • Superior/inferior • Anterior/posterior • Medial/lateral • Superficial/deep © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. 3 8/24/13 Table 1.1 Orientation and Directional Terms (2 of 2) Body Planes and Sections • Frontal (coronal) plane • Lies vertically and divides body into anterior and posterior parts • Transverse plane • Runs horizontally and divides body into superior and inferior parts © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Figure 1.4 Planes of the body with corresponding magnetic resonance imaging (MRI) scans. Body Planes and Sections Median section (midsagittal) Frontal plane • Sagittal planes Median (midsagittal) plane • Are vertical • Divide the body into right and left parts Transverse plane • Median (midsagittal) plane • Sagittal plane that runs along the midline • Parasagittal planes Rectum Intestines Vertebral column Frontal section (through torso) Transverse section (through torso, inferior view) • A sagittal plane offset from the midline Spleen Liver © 2014 Pearson Education, Inc. Subcutaneous fat layer Liver Stomach Left and right lungs Heart Arm © 2014 Pearson Education, Inc. Spinal cord Aorta Pancreas Body wall Figure 1.5a Basic human body plan, indicated by structures shared among all vertebrates. The Human Body Plan • Tube-within-a-tube • Bilateral symmetry • Dorsal hollow nerve cord Inner tube Dorsal hollow nerve tube Segmented outer tube Notochord Notochord Spinal cord Muscle segments (myotomes) Brain • Notochord and vertebrae • Segmentation • Pharyngeal pouches © 2014 Pearson Education, Inc. Pharyngeal pouches Heart Digestive tube Generalized vertebrate © 2014 Pearson Education, Inc. 4 8/24/13 Figure 1.5b Basic human body plan, indicated by structures shared among all vertebrates. Inner tube Dorsal hollow nerve tube Segmented outer tube Notochord Pharyngeal pouches Figure 1.5c Basic human body plan, indicated by structures shared among all vertebrates. Brain Pharynx Lung bud Spinal cord Muscle segments (muscles between ribs) Spinal cord Notochord Heart Vertebrae Muscle segments (myotomes) Brain Heart Digestive tube Disc between vertebrae Digestive tube Inner tube Dorsal hollow nerve tube Segmented outer tube Notochord Human embryo; 5 weeks postconception Adult human © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Body Cavities and Membranes Body Cavities and Membranes • Dorsal body cavity • Ventral body cavity • Cranial cavity • Vertebral cavity • Thoracic cavity—divided into three parts • Two lateral parts, each containing a lung surrounded by a pleural cavity • Mediastinum—contains the heart surrounded by the pericardial sac © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Figure 1.6a Dorsal and ventral body cavities and their subdivisions. Dorsal body cavity Body Cavities and Membranes • Ventral body cavity—continued • Abdominopelvic cavity—divided into two parts • Abdominal cavity—contains the liver, stomach, kidneys, and other organs Ventral body cavity Cranial cavity (contains brain) Thoracic cavity (contains heart and lungs) Dorsal body cavity Vertebral cavity (contains spinal cord) • Pelvic cavity—contains the bladder, some reproductive organs, and rectum Diaphragm Abdominal cavity (contains digestive viscera) Pelvic cavity (contains urinary bladder, reproductive organs, and rectum) Lateral view © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. 5 8/24/13 Figure 1.6b Dorsal and ventral body cavities and their subdivisions. Dorsal body cavity Ventral body cavity Cranial cavity • Serous cavities—a slitlike space lined by a serous membrane Vertebral cavity Thoracic cavity (contains heart and lungs) Superior mediastinum • Pleura, pericardium, and peritoneum Pleural cavity • Parietal serosa Pericardial cavity within the mediastinum Diaphragm Abdominopelvic cavity Abdominal cavity (contains digestive viscera) Pelvic cavity (contains urinary bladder, reproductive organs, and rectum) © 2014 Pearson Education, Inc. Body Cavities and Membranes Ventral body cavity (thoracic and abdominopelvic cavities) Anterior view • Outer wall of the cavity • Visceral serosa • Covers the visceral organs © 2014 Pearson Education, Inc. Figure 1.7a The serous cavities and their associated membranes. Body Cavities and Membranes Lung • Serous fluid Ribs Parietal pleura • Produced by both layers of the serous membranes Pleural cavity with serous fluid Visceral pleura Diaphragm Serosae associated with the lungs: pleura © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Figure 1.7b The serous cavities and their associated membranes. Figure 1.7c The serous cavities and their associated membranes. Heart Anterior Parietal pericardium Pericardial cavity with serous fluid Visceral pericardium Serosae associated with the heart: pericardium © 2014 Pearson Education, Inc. Visceral peritoneum Peritoneal cavity (with serous fluid) Stomach Liver Parietal peritoneum Kidney (retroperitoneal) Wall of body trunk Serosae associated with the abdominal viscera: peritoneum Posterior © 2014 Pearson Education, Inc. 6 8/24/13 Figure 1.7d The serous cavities and their associated membranes. Abdominal Regions and Quadrants • Abdominal regions divide the abdomen into nine regions Outer balloon wall (comparable to parietal serosa Air (comparable to serous cavity) Inner balloon wall (comparable to visceral serosa) • Abdominal quadrants divide the abdomen into four quadrants • Right upper and left upper quadrants Model of the serous membranes and serous cavity • Right lower and left lower quadrants © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. 9 Abdominal Regions 4 Abdominal Quadrants Diaphragm Spleen Stomach Liver Right Left Epigastric hypochondriac hypochondriac region region region Right lumbar region Umbilical region Left lumbar region Right iliac Hypogastric Left iliac (inguinal) (pubic) (inguinal) region region region Gallbladder Transverse colon of large intestine Descending colon of large intestine Initial part of sigmoid colon Ascending colon of large intestine Small intestine Cecum Appendix Left upper quadrant (LUQ) Right lower quadrant (RLQ) Left lower quadrant (LLQ) Urinary bladder (b) Anterior view of the nine regions showing the superficial organs (a) Nine regions delineated by four planes © 2014 Pearson Education, Inc. Right upper quadrant (RUQ) Figure 1.8a, b Microscopic Anatomy (c) The four abdominopelvic quadrants © 2014 Pearson Education, Inc. Microscopic Anatomy Cytoplasm • Microscopy—examining small structures through a microscope • Light microscopy illuminates tissue with a beam of light (lower magnification) Figure 1.8c Cell nuclei Extracellular material (a) Light micrograph (330×) • Electron microscopy uses beams of electrons (higher magnification) (c) Scanning electron micrograph, artificially colored (2900×) (b) Transmission electron micrograph, artificially colored (870×) © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Figure 1.9a–c 7 8/24/13 Microscopic Anatomy Microscopic Anatomy • Preparing human tissue for microscopy • Scanning electron microscopy • Specimen is fixed (preserved) and sectioned • Specimen is stained to distinguish anatomical structures • Heavy metal salt stain—deflects electrons in the beam to different extents • Artifacts • Minor distortions of preserved tissues • Acidic stain—negatively charged dye molecules • Not exactly like living tissues and organs • Basic stain—positively charged dye molecules © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Figure 1.10 X-ray images. Clinical Anatomy—An Introduction to Medical Imaging Techniques • X ray—electromagnetic waves of very short length • Best for visualizing bones and abnormal dense structures Clavicles (collarbones) Ribs Air in lungs (black) Heart Diaphragm Radiograph of the chest © 2014 Pearson Education, Inc. Lower GI with barium contrast medium, normal © 2014 Pearson Education, Inc. Figure 1.11 Computed tomography (CT). Advanced X-Ray Techniques Right • Computed (axial) tomography (CT or CAT) • Takes successive X rays around a person s full circumference View Left Liver Stomach Colon Inferior vena cava Aorta Spleen • Computer translates recorded information into a detailed picture of the body section Left kidney Thoracic vertebra © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. 8 8/24/13 Figure 1.12 Digital subtraction angiography (DSA). Advanced X-Ray Techniques Narrowing of artery Artery supplying heart • Positron emission tomography (PET)— forms images by detecting radioactive isotopes injected into the body • Sonography (ultrasound imaging)—body is probed with pulses of high-frequency sound waves that echo off the body s tissues • Imaging technique used to determine the age of a developing fetus © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Figure 1.13 Positron Emission Tomography (PET). Figure 1.14 Ultrasound image of a fetus in the uterus. Brain Heart Liver Kidney Colon Urinary bladder Head Body PET scan before treatment. Tumors visible in right breast and in liver PET scan after treatment © 2014 Pearson Education, Inc. © 2014 Pearson Education, Inc. Figure 1.15 Magnetic resonance image (MRI). Advanced X-Ray Techniques • Magnetic resonance imaging (MRI)— produces high-quality images of soft tissues Normal knee, meniscus intact • Distinguishes body tissues based on relative water content Injured knee, torn meniscus MRI of knee, sagittal section. Arrow indicates meniscus. Note tear in meniscus in bottom image. © 2014 Pearson Education, Inc. Volume rendering of an MRI of the head © 2014 Pearson Education, Inc. 9