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Transcript
Introduction to Basic Therapeutics Module Dr. Naser Ashraf Tadvi Module coordinator Objectives • Describe the concept of Module, including objectives, learning contents, teaching and learning methodology, practicals, references, assessment, and all module related matter • Understand computer assisted learning in experimental Pharmacology • Briefly overview the concept of pharmacology Concept of the Module Theme I: Different Therapeutic Modalities • Introduction to different therapeutic modalities. • Non-pharmacological basis of therapy (e.g. physiotherapy, occupational therapy, radiotherapy, counseling & CAM) • Introduction to pharmacotherapeutics Theme II: How body handles drugs (Pharmacokinetics): Absorption. Distribution. Metabolism. Elimination. How drug acts (Pharmacodynamics): Receptors (affinity, efficacy & potency). Theory of drug receptors binding. Signal transduction apparatus. Therapeutic index and therapeutic window Individual variations in drug response (pharmacogenomics) Introduction to Pharmacogenomics. Clinical relevance of Pharmacogenomics Theme III: Autonomic Pharmacology & Autocoids Autonomic nervous system drugs • Adrenergic agonists & antagonists. • Cholinergic agonists & antagonists. • Skeletal muscles relaxants. Autacoids (histamine, serotonin & prostaglandins) • Histamine and antihistamines • Serotonin and anti–serotonin • Prostaglandins and ergot alkaloids Theme IV: Rational & safe prescription including drug development • • • • • • • • • • Drug therapy during pregnancy & lactation Drug therapy in the geriatric & pediatric groups. Adverse drug reaction (ADR). Principles of toxicology. Drug interactions Safe prescribing habits. Cost effective drug therapy. Compliance & adherence Monitoring of drug treatment National & international drug evaluation & regulation Teaching and learning methods • • • • • • • Lectures: 30 PBL: 4 CD: 5 Seminars: 5 Practicals: 6 Tutorial: 2 Field Visit: 1 Practicals • All practicals have Computer Assisted Learning • At the end of each practical the students will be evaluated in the last half hour • The quiz for each practical will be of ten marks • MCQs or SEQs related to practical can be asked • There will be no separate mid term practical exam • 10 % of these marks will be considered as midterm practical exam marks Assessment • Continuous Assessment • Final Assessment 60% 40% Continuous assessment Mid Module exam Multiple choice questions Short essay questions Activities Marks Problem Based Learning (PBLs) Case Discussion (CDs) Quiz PBL, CDs, Seminars Seminar Mid Term Practical Exam 60 marks 40 Marks 20 % 40 MCQs 05 SEQs 30 % 160 Marks 04 PBLs 75 Marks 05 CDs 40 Marks 100 Marks Practical 2,3,4 30 Marks 04 Quiz 01 Seminar 10% of this Mid module exam (will cover) • • • • Lecture 1 to lecture 15 PBL 1 & PBL 2 CD 1 & CD 2 Seminar 1 & Seminar 2 Quizzes (10 marks each) • Quiz 1 – PBL 1, CD1, Seminar 1 • Quiz 2 – PBL 2, CD2, Seminar 2 • Quiz 3 – PBL 3, Seminar 3, CD 3 • Quiz 4 – PBL 4, Seminar 4, seminar 5, CD4, CD5 Final Assessment Final Assessment Final module examination Multiple choice questions Short essay questions Final Practical examination 60 marks 40 Marks 40 % 30 % 60 MCQs 05 SEQs 10 % Attendance • 75 % attendance is compulsory for eligibility in exam • PBLs, CDs, quizzes, practical's and Seminars absence will lead to loss of marks in continuous assessment Concept of Pharmacology • Drug therapy involves a great deal more than matching the name of the drug to the name of a disease; it requires knowledge, judgement, skill and wisdom, but above all a sense of responsibility. Learning resources • Illustrated reviews Pharmacology, Ed. Lippincott. 5th Edition, • Katzung & Trevor’s Basic and Clinical Pharmacology. 12th Edition, • Reference book: – Goodman & Gilman Pharmacological Basis of Therapeutic 2011- 12th Edition At the end of module