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Fertilization and Embryo Develpment ສອນໂດຍ ອາຈານ ສນຕ ັ ິ ນາມມະວງສາ ົ ຂະແໜງການວໄິ ຈແລະ ທດ ົ ລອງສດ ັ What is a cell ? • Cells are the basic building blocks of all living things. The human body is composed of trillions of cells. They provide structure for the body, take in nutrients from food, convert those nutrients into energy, and carry out specialized functions. Cells also contain the body’s hereditary material and can make copies of themselves. • Cells have many parts, each with a different function. Some of these parts, called organelles, are specialized structures that perform certain tasks within the cell • Most of cell are made up of the cytoplasm and the nucleus • The nucleus is the spherical body more or less the center of the cell. Be to the heart and brain of cell because it carries genetic material and body function • The cytoplasm contain many secretion production such as lipid droplets and highly special structure called Organelles which play important in cell function • Ribosome are the organelles in cytoplasm where the amino acid are assembled to form protein • Mitochondria are organelles for regenerating energy of the cell in the form Adenosine Triphosphate (ATP). Mitochondria contain the nucleic acid (RNA and DNA) • Lysosomes are small, usually spherical body that contain digestive enzyme which break down the major constituent of living organisms called “suicide bags” • Polymorph-nuclear leucocytes contain lysosomes and these cell have ability to phagocytize bacteria or other foreign substance which might enter the blood stream Spermatogenesis • Spermatogenesis is the process in which spermatozoa are produced from male primordial germ cells by way of mitosis and meiosis. The initial cells in this pathway are called spermatogonia. • Spermatogenesis produces mature male gametes, commonly called sperm, which are able to fertilize the counterpart female gamete • Spermatogenesis takes place within several structures of the male reproductive system (seminiferous tubules) Spermatogenesis • Spermatocytogenesis, a diploid spermatogonium, which resides in the basal compartment of the seminiferous tubules, divides mitotically, producing two diploid intermediate cells called primary spermatocytes. • Each primary spermatocyte then moves into the adlumainal compaertment the seminiferous tubules and duplicates its DNA and subsequently undergoes meiosis to produce two haploid secondary sperma - tocyte Spermatogenesis http://www.usi.edu/science/biology/mkhopper/ap_labs/2402/Reproductive%20Physiology/Spermatogenesis.htm Oogenesis process • Just like spermatogenesis, oogenesis involves the formation of haploid cells from an original diploid cell, called a primary oocyte, through meiosis. • The female ovaries contain the primary oocytes. There are two major differences between the male and female production of gametes. • First of all, oogenesis only leads to the production of one final ovum, or egg cell, from each primary oocyte of the four daughter cells that are produced when the primary oocyte divides meiotically, three come out much smaller than the fourth. • These smaller cells, called polar bodies, eventually disintegrate, leaving only the larger ovum as the final product of oogenesis. The production of one egg cell via oogenesis normally occurs only once a month, from puberty to menopause. • Oogonium —(Oocytogenesis)—> Primary Oocyte — (Meiosis I)—> First Polar Body (Discarded afterward) + Secondary oocyte —(Meiosis II)—> Second Polar Body (Discarded afterward) + Ovum Embryo development Embryo development Embryo development th 13 day Embryo development http://www.mahjoob.com/en/forums/275459-3-let-there-light/ Embryonic development Differentiation • Ectoderm • Mesoderm • Endoderm Ectoderm ່ີ ຢ • ເປ ູ່ ພາຍນອກສາມາດພັດທະນາມາ ັ ນສ ່ ວນທ ເປ ັ ນ – ລະບ ົ ບປະສາດ – ອະໄວຍະວະຮັບຄວາມຮ ູ ້ ຶ ສກ ້ າຊ – ອະໄວຍະວະປ ຸ ້ ມ ແລະ ໍຄ ົ ກຫ ່ າງກາຍ ູ ຮ Mesoderm • ສາມາດພັດທະນາມາເປ ັ ນ: –ກ ້ າມຊ ີ້ ນ –ຜ ິ ວໜັງ – ລະບ ່ າຍ ົ ບຂັບຖ – ລະບ ື ບພັນ ົ ບສ – ເສ ື ອດ ັ້ ນເລ ່ື ອບ – ເຍ ຸ ຕ ່ າງໆໃນຮ ່ າງກາຍ Endoderm • ພັນທະນາໄປເປ ັ ນ: ່ື ອບ – ເຍ ຸ ໃນລະບ ິ ນອາຫານ ົ ບທາງເດ – ລະບ ົ ບຫາຍໃຈ –ສ ່ ວນຂອງຕັບ – ຕັບອ ່ ອນ –ຕ ່ ອມໄທລອຍ – ກະເພາະປັດສະວະ ່ື ອບ – ເຍ ຸ ກະເພາະປັດສະວະ Reference • P.G.C. BEDFORD; 2001. Atlas of Canine surgical Technique. Veterinary College Field Station. (ພາສາອັງກ ິ ດ) • ກ,ງໄກ ໄພຣນ ູ ດຊາກສັດ. ຄະນະສັດຕະວະແພດ. ່ າພ ິ ຣັນກ ິ ດ. 2001. ການຜ ິ ສ ມະຫາ ິ ວທະຍາໄລກະເສດສາດ. ິ ວທະຍາເຂດບາງເຂນ. (ພາສາໄທ) • ຄະນະກະເສດສາດ. 2002. ເອກະສານປະກອບການສອນວ ຸ ງພັນ ິ ຊາ: ການປັບປ ສັດ ແລະ ປະດ ຸ ງຄັນ. ມະຫາວ ່ ງຊາດ. ກະຊວງສ ິ ທະຍາໄລແຫ ຶ ກສາທ ິ ການ. • ນັດທະພອນ ຂາລ ູ ພັນ. 2009. ິ ວຊາສັດຕະວະສາດ. ຄະນະວ ິ ທະຍາສາດ. ມະຫາວ ິ ທະ ຍາ ໄລກະເສດສາດ. ິ ວທະຍາເຂດບາງເຂນ. (ພາສາໄທ) Anything’s to ask