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Transcript
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© Boardworks Ltd 2008
The cardiac cycle
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Interactive heart
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Cardiac output
The amount of blood pumped around the body is called the
cardiac output, and depends on two factors:

the stroke volume – the volume of blood pumped by
the left ventricle in each heart beat. A typical value for an
adult at rest is 75 ml.

the heart rate – the number of times the heart beats per
minute. A typical value for an adult at rest is 70 bpm.
cardiac output = stroke volume × heart rate
A typical resting cardiac output is 4–6 litres per minute.
This can rise to as much as 40 litres per minute in highly
trained endurance athletes.
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Pacemaker cells of the heart
The heart can beat without any input from the nervous
system as longs as its cells stay alive. This is due to
myogenic contraction.
Muscle cells (myocytes) in the heart have a slight
electrical charge across their membrane. They are
polarized. When the charge is reversed, they are said to
be depolarized and this causes them to contract.
Depolarization is initiated in a region of the heart called the
sinoatrial node (SAN) – also known as the pacemaker –
which is in the wall of the right atrium.
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Myogenic stimulation of the heart
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Interactive heart
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Artificial pacemakers
Artificial pacemakers are devices implanted in people
whose heart’s electrical conduction system is not working
properly.
Problems include the SAN not firing, and the blockage or
disruption of impulses between the SAN and AVN, or in the
bundle of His.
Pacemakers monitor the
heart’s electrical activity and
stimulate the ventricles or atria
to contract when necessary.
Impulses are transmitted
down electrodes implanted in
the muscular walls.
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The cardiac cycle
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What are electrocardiograms?
The electrical activity of the heart can be monitored by
an electrocardiograph.
Several electrodes are
attached to specific places
on a person’s chest and
limbs. These detect
changes in polarization in
the heart by measuring
current at the skin surface.
The leads are connected to
a machine that draws an
electrocardiogram (ECG).
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Components of an ECG trace
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ECG in diagnosis
ECGs are used to diagnose problems with the heart, as
variations in different components of the trace can
indicate a disease or other abnormality.
An ECG may be taken
while the patient is relaxed
or it may be taken before,
during and after exercise.
This is called a ‘stress test’
and usually involves the
patient exercising on a
treadmill while attached to
an ECG machine.
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Abnormal ECGs
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