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Transcript
Respiratory distress in the newborn
Respiratory distress is encountered frequently in newborns.
respiratory distress in the newborn may be a potentially lifethreatening condition,.
The key to successful management includes a complete
maternal and newborn history, perform a thorough physical
examination, recognize the common respiratory disorders,
differentiate among various diagnostic entities, and identify those that
are life-threatening.
Respiratory distress in the newborn is characterized by one or
more of the following:
nasal flaring,
chest retractions,
tachypnea,
grunting
An infant who has an advanced degree of respiratory distress may
exhibit additional signs,
cyanosis,
gasping,
choking,
apnea,
stridor.
Initial assessment
The aim of the initial assessment of the infant in respiratory distress is to
identify life-threatening conditions that require prompt support,
Alarming" Signs of Life-threatening Conditions
Obstructive Airway
Gasping
Choking
Stridor
Insufficient Breathing Apnea
Poor respiratory effort
Circulatory Collapse
Bradycardia
Hypotension
Poor perfusion
Poor Oxygenation
Cyanosis
HISTORY
Results of fetal assessment during pregnancy (triple screen,
ultrasonography, biophysical profile)
Fetal monitoring during labor and delivery (fetal heart rate, beat-tobeat variability, presence of decelerations)
Complications at delivery (eg, birth trauma, presence of meconium,
perinatal depression)
Maternal and obstetric conditions associated with respiratory distress in neonates
Details of the presenting respiratory symptoms
A history of coughing and choking in relation to feeding
A maternal history of polyhydramnios
Choking after feeding
History of recurrent emesis.
Gradually improving symptoms
Gradual deterioration
Physical examination
Inspection
Cyanosis
Respiratory rate
Retractions
Apnea
Inspiratory stridor
Asymmetric chest movement
A scaphoid abdomen Auscultation
Symmetry and adequacy of air exchange Abnormal breath sounds
Heart murmur
Transillumination
Differential Diagnosis
Parenchymal lung diseases,
Pneumonia,
Surfactant deficiency,
Meconium aspiration,
Congenital heart diseases
Neurologic disorder
Seizures, asphyxia, and meningitis
Metabolic causes
Hypoglycemia and acidosis
Hypothermia, sepsis, acidosis, polycythemia, or anemia.
Airway and chest wall deformities as well as abnormalities of the
diaphragm and mediastinal structures
Transient Tachypnoea of Newborn
TTN represents transient pulmonary edema resulting from
delayed clearance of fetal lung liquid.
It can occur in both term and preterm neonates.
Seen in babies delivered by C-Section
Clinical Presentation
Grunting
nasal flaring immediately after birth
Chest Xray
increased interstitial markings and occasionally fluid in the interlobar
fissures
Arterial blood gases reveal respiratory acidosis and mild-tomoderate hypoxemia
TTN is generally a benign, self-limited disease
responds well to oxygen therapy.
Mechanical ventilation seldom is needed.
Full recovery is expected within 2 to 5 days.
Meconium Aspiration Syndrome
Meconium staining of amniotic fluid occurs in approximately 10% to
26% of all deliveries
Seen almost exclusively in term and postterm deliveries.
Passage of meconium in utero may represent fetal hypoxemia.
Meconium can be aspirated before, during, or after delivery.
Once aspirated, meconium can cause obstruction of the air
passages, chemical pneumonitis with activation of
several inflammatory mediators, and inactivation of lung surfactant.
Presentation
Varying degrees of respiratory distress
A "barrel chest"
Audible rales or rhonchi on auscultation
The chest radiograph usually shows patchy areas of atelectasis
alternating with areas of overinflation
Pneumothorax is seen in 10% to 20% of infants who have MAS.
Hyaline Membrane disease
Common condition in preterm infants.
The cause is insufficient pulmonary surfactant, produced by type II
pneumocytes.
It reduces the surface tension inside the alveoli, preventing them
from collapsing.
The blood gas typically reveals hypoxemia and respiratory acidosis.
Chest XRay lungs demonstrate the typical "ground
glass" appearance and "air bronchograms"
Prevention of HMD to continue gestation or treatment with antenatal
steroids
Affected infants often are managed with mechanical ventilation and
endotracheal surfactant replacement therapy
The use of continuous positive airway pressure is a less invasive
alternative.
PNEUMONIA
The most common infection in neonates,
Can be due to different antenatal, perinatal, or postnatal causes.
Pneumonia can present with a diversity of
signs in infancy, including any form of respiratory distress,
lethargy, poor feeding, jaundice, or apnea. Temperature instability.
Chest Xray
Bilateral consolidation
Patchy involvement
TREATMENT
Treat respiratory distress with antibiotics until pneumonia is ruled out
Congenital Heart Diseases
Important to differentiate from pneumonia
The two can co-exist
Presence of murmer doesn’t exclude pneumonia
Meconium staining of amniotic fluid doesn’t rule out CHD
Signs that generally are consistent with CHD
:
Visibly hyperactive precordial impulse, gallop rhythm,
poor capillary refill,
weak pulses,
decreased or delayed pulses in lower extremities,
hepatomegaly,
Differentiation of CHD from Pulmonary diseases
CHD
History
previous sibling
Prenatal Echo
Findings
Cyanosis
Gallop sound
Split second sound
Large liver
Mild respiratory distress
Chest Radiograph
Increased heart size
Decreased pulmonary vascularity
Arterial Blood Gases
Dec.PO2
N-Dec PCO2
Dec.PO2
Inc.PCO2
Hyperoxia test
PO2<150
Echocardiography
Abnormal heart and vessels
Pulmonary diseases
Maternal fever
Meconium-staining Preterm delivery
Severe retraction
Single second heart
Fever
Cyanosis
Chest Radiograph
Normal heart size
Abnormal parenchyma
Arterial Blood Gases
Dec.PO2
Inc.PCO2
Hyperoxia test
PO2>150
Echocardiography
Normal heart and vessels
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