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Download 3 Lecture Spinal Cord (Internal Structure)
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Lecture 3 Spinal Cord (Internal Structure) TRACTS OF SPINAL CORD The white matter of the spinal cord consist of a mixture of Nerve fibers and are arranged in tracts and for purpose of description, spinal tracts are divided into: - Ascending tracts - Descending tracts - Intersegmental tracts Considerable overlap between tracts are present - Transverse section of the spinal cord at the midcervical level showing the general arrangement of the ascending tracts on the right and the descending tracts on the left Ascending Tracts - On entering the spinal cord, the sensory nerve fibers of different sizes and functions are sorted out and segregated into nerve bundles or tracts in the white matter Some of the nerve fibers serve to link different segments of the spinal cord, while others ascend from the spinal cord to higher centers and thus connect the spinal cord with the brain - The information (of the ascending pathway) may be divided into two main groups: (1) exteroceptive information, which originates from outside the body, such as pain, temperature, and touch. (2) proprioceptive information, which originates from inside the body, for example, from muscles and joints. ANATOMICAL ORGANIZATION first-order neuron second-order neuron third-order neuron - This three-neuron chain is the most common arrangement, but some afferent pathways use more or fewer neurons - - Many of the neurons in the ascending pathways branch and give a major input into the reticular formation, which, in turn, activates the cerebral cortex, maintaining wakefulness. Other branches pass to motor neurons and participate in reflex muscular activity Pain and Temperature Pathways - Lateral spinothalamic tract. (contribute to posterolateral tract of Lissauer) - Axons of 2nd order n. cross obliquely to the opposite side within one spinal segment, 2nd order neuron located at substania gelatinosa, at higher level at medulla oblongata it accompanied with ant. spinothalamic and spinotectal tracts to form the Spinal lemniscus that ascending through the posterior part of Pons then end of this neuron at thalamus, 3rd order neuron then pass through post. limb of internal capsule and the corona radiata to reach the somesthetic area of precentral gyrus of cerebral cortex Types of pain, - fast pain and slow pain - - Light (Crude) Touch and Pressure Pathways Anterior Spinothalamic Tract - - The axons enter the spinal cord from the posterior root ganglion divide into ascending and descending branches travel for a distance of one or two segments of the spinal cord, The axons of the second-order neuron cross very obliquely to the opposite side in the anterior gray and white commissures within several spinal segments and ascend in the opposite anterolateral white column as the anterior spinothalamic tract contributing to the posterolateral tract of Lissauer form part of spinal lemniscus - - Transverse section of the spinal cord at the midcervical level showing the general arrangement of the ascending tracts on the right and the descending tracts on the left Discriminative Touch, Vibratory Sense, and Conscious Muscle Joint Sense Posterior White Column: Fasciculus Gracilis and Fasciculus Cuneatus They are separated by a septum Ascending ipsilateraly and 2nd order n. terminate and synapse at gracilis and cunatus nuclei Decussation occur as sensory decussation to form medial lemniscus at level of medulla oblongata pass to thalamus and 3rd order n. to somesthetic area of precentral gyrus of cerebral cortex Muscle Joint Sense Pathways to the Cerebellum Posterior Spinocerebellar Tract (2nd order n – nucleus dorsalis (Clarke's column) Anterior Spinocerebellar Tract (nucleus dorsalis) Cuneocerebellar Tract originate in the nucleus cuneatus and enter the cerebellum through the inferior cerebellar peduncle of the same side The fibers are known as the posterior external arcuate fibers, and their function is to convey information of muscle joint sense to the cerebellum Other Ascending Pathways Spinotectal Tract (afferent information for spinovisual reflexes and brings about movements of the eyes and head toward the source of the stimulation) Spinoreticular Tract (The spinoreticular tract provides an afferent pathway for the reticular formation, which plays an important role in influencing levels of consciousness) Spino-olivary Tract (conveys information to the cerebellum from cutaneous and proprioceptive ) Visceral Sensory Tracts THE DESCENDING TRACTS ANATOMICAL ORGANIZATION first-order neuron second-order neuron third-order neuron Corticospinal tracts - Fibers of the corticospinal tract arise as axons of pyramidal cells situated in the fifth layer of the cerebral cortex - Pass within Corona radiata - then pass within internal capsule (the fibers are organized so that those closest to the genu are concerned with cervical portions of the body, while those situated more posteriorly are concerned with the lower extremity) - basis pedunculi of the midbrain - in pons, the tract is broken into many bundles by the transverse pontocerebellar fibers - In the medulla oblongata, the bundles become grouped together along the anterior border to form a swelling known as the pyramid (pyramidal tract) At the junction of the medulla oblongata and the spinal cord, most of the fibers cross the midline at the decussation of the pyramids and enter the lateral white column - lateral corticospinal tract - anterior corticospinal tract - - - Reticulospinal Tracts From a collection of nerves at the midbrain, pons, and medulla oblongata called the reticular formation - pontine reticulospinal tract - medullary reticulospinal tract Surve as a pathway by which the hypothalamus can control the sympathetic outflow and the sacral parasympathetic outflow Tectospinal Tract Fibers of this tract arise from nerve cells in the superior colliculus of the midbrain These fibers are believed to be concerned with reflex postural movements in response to visual stimuli Rubrospinal Tract the red nucleus is situated in the tegmentum of the midbrain at the level of the superior colliculus tract facilitates the activity of the flexor muscles and inhibits the activity of the extensor or antigravity muscles Vestibulospinal Tract The vestibular nuclei are situated in the pons and medulla oblongata beneath the floor of the fourth ventricle this tract, facilitate the activity of the extensor muscles and inhibit the activity of the flexor muscles in association with the maintenance of balance Olivospinal Tract Descending Autonomic Fibers The higher centers of the central nervous system associated with the control of autonomic activity are situated in the cerebral cortex, hypothalamus, amygdaloid complex, and reticular formation Intersegmental Tracts Short ascending and descending tracts that originate and end within the spinal cord exist in the anterior, lateral, and posterior white columns. The function of these pathways is to interconnect the neurons of different segmental levels, and the pathways are particularly important in intersegmental spinal reflexes REFLEX ARC A reflex may be defined as an involuntary response to a stimulus. It depends on the integrity of the reflex arc. In its simplest form, a reflex arc consists of the following anatomical structures: (1) a receptor organ, (2) an afferent neuron, (3) an effector neuron, (4) an effector organ SPINAL CORD SYNDROM 1- Complete cord transection 2- ant. cord syndrom 3- central cord syndrom 4- Brown squard syndrom - -