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Biometry Assignment #5 ~ Applications of Sampling Distributions: CI’s and Decision Making (Due 2/25/11) 1. In a random sample of 1215 animals, 362 exhibited a certain trait defect. Determine the 95% confidence interval for the proportion of the population displaying the trait. Also give the correct interpretation of this interval. (5 pts.) 2. A severe drought in 1987 affected both the death rate of seedlings and the growth rate of established trees. It is thought that a majority of the trees in the affected areas have a 1987 growth ring that is less than one half the size of the trees' other growth rings. A sample of 250 trees yielded 150 with this characteristic. Do these data support the claim that a majority of trees exhibited the growth defect? (5 pts.) 3. A topic of recent clinical interest is the possibility of using drugs to reduce the infarct size in patients who have had a myocardial infarction within the past 24 hours. Suppose we know that in untreated patients the mean infarct size is 25 (ck-g-EQ/m2). In a study of 25 patients treated with a drug the mean infarct size is 16 (ck-g-EQ/m2) with a standard deviation of 12.5. Do these results provide “statistically significant” evidence that the drug is effective in reducing infarct size? Show all your work and justify your answer. (5 pts.) 4. Renal Blockage A study is run to determine the effects of removing a renal blockage in patients whose renal function is impaired because of advanced metastatic malignancy of nonurologic cause. The arterial blood pressure in each patient is measured before (X) and after (Y) surgery. The results are in the table below. Patient Before (X) After (Y) Difference (X – Y) 1 150 90 2 132 102 3 130 80 You will probably want to 4 116 82 enter these differences into 5 107 90 JMP and use Distribution to 6 100 94 obtain the necessary summary 7 101 84 statistics. 8 96 93 9 90 89 10 78 85 Find a 95% CI for the mean change in the arterial blood pressure of this population of patients after having undergone surgery. Interpret this interval. Does this suggest that the arterial blood pressure of these patients on average decreases after surgery? Explain. (5 pts.)