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Stable isotope 59 Co Relative atomic mass 58.933 194 Mole fraction 1 Cobalt isotopes in industry 60 Co is used to irradiate food sources as a method of preserving food (Figure 1). The gamma radiation from 60Co kills bacteria and other organisms that cause disease and spoilage of food (see Figure 1). The use of radioactive compounds for preserving food is not always viewed positively. Some individuals are concerned that harmful compounds will be produced during the irradiation process. However, there is no evidence to support the fact that irradiation is a dangerous method of food preservation [66, 102, 220-222]. Many medical products today are sterilized using gamma rays from a 60Co source. This technique of sterilization is generally much cheaper and more effective than steam-heat sterilization because it is a cold process. For example, it can be performed on packaged items, such as disposable syringes. This sterilization technique is applicable to a wide range of heatsensitive items, such as powders, ointments, and solutions, as well as biological preparations, such as bone, nerve, skin, etc., used in tissue grafts [66, 102, 220-222]. 60 Co is also used in industrial radiography to detect structural flaws in metal parts. The radiation can penetrate metals and the X-ray pattern produced by the radiating material can provide information on its strength, composition, and other properties [66, 102, 220-222]. Because of the above property, 60Co is also used in leveling devices and thickness gauges used to test welds and castings [66, 102, 220-222]. Fig. 1: Plants growing in the gamma greenhouse at Brookhaven National Laboratory. The plants are arranged in concentric rings around the radioactive 60Co source, which is in the pipe extending into the floor (circa 1959) [223]. (Photo Source: LSF Magazine). Cobalt isotopes in medicine 60 Co is a radioactive metal isotope that is used in cancer treatments by radiotherapy. When 60Co undergoes radioactive decay, high-energy gamma rays (energies of 1.17 MeV and 1.33 MeV) are emitted and can be used in brachytherapy to treat various types of cancer. Brachytherapy (brachy- is Greek meaning “short distance”) is a method of radiation treatment in which sealed sources are used to deliver a radiation dose at a distance of up to a few centimeters by surface, intracavitary (insertion of the radioactive isotope in a body cavity), or interstitial (between cells) application [66, 90, 220, 221, 224]. 60Co is used as a source of high-energy ionizing gamma radiation that can be directed to cancer cells from a device outside the body (external radiotherapy) [66, 90, 220, 221, 224]. 60 Co (and sometimes 57Co and 58Co) is the key component of the Schilling test, which is a method for determining whether a patient’s body is making and using vitamin B12 properly. The cobalt isotope is used to label cobalt in vitamin B12 to monitor how the body processes this essential vitamin [66, 90, 220, 221, 224]. 57 Co delivers the smallest radiation dose of all the cobalt isotopes. As a result, it has been used in the past for imaging and estimating organ size and location and in evaluating tumors of the head and neck [66, 90, 220, 221, 224]. Glossary atomic number (Z) – The number of protons in the nucleus of an atom. brachytherapy – the treatment of cancer, especially prostate cancer, by the insertion of radioactive implants directly into the tissue near the tumor. [return] electron – elementary particle of matter with a negative electric charge and a rest mass of about 9.109 × 10–31 kg. element (chemical element) – a species of atoms; all atoms with the same number of protons in the atomic nucleus. A pure chemical substance composed of atoms with the same number of protons in the atomic nucleus [703]. gamma rays (gamma radiation) – a stream of high-energy electromagnetic radiation given off by an atomic nucleus undergoing radioactive decay. The energies of gamma rays are higher than those of X-rays; thus, gamma rays have greater penetrating power.[return] half-life (radioactive) – the time interval that it takes for the total number of atoms of any radioactive isotope to decay and leave only one-half of the original number of atoms. ionizing – pertaining to the process by which an atom, molecule, or substance acquires a negative or positive charge. Commonly, one or more electrons are removed to give a negative charge. [return] isotope – one of two or more species of atoms of a given element (having the same number of protons in the nucleus) with different atomic masses (different number of neutrons in the nucleus). The atom can either be a stable isotope or a radioactive isotope. [return] neutron – an elementary particle with no net charge and a rest mass of about 1.675 × 10–27 kg, slightly more than that of the proton. All atoms contain neutrons in their nucleus except for protium (1H). proton – an elementary particle having a rest mass of about 1.673 × 10–27 kg, slightly less than that of a neutron, and a positive electric charge equal and opposite to that of the electron. The number of protons in the nucleus of an atom is the atomic number. radioactive decay – the process by which unstable (or radioactive) isotopes lose energy by emitting alpha particles (helium nuclei), beta particles (positive or negative electrons), gamma radiation, neutrons or protons to reach a final stable energy state. [return] radioactive isotope (radioisotope) – an atom for which radioactive decay has been experimentally measured (also see half-life). [return] radiography – an imaging technique that uses electromagnetic radiation other than visible light, especially X-rays and gamma rays, to view the internal structure of non-uniform objects, such as metal parts, welded pipes, and the human body. [return] radiotherapy (radiation therapy) – the treatment of disease by means of radiation from radioactive substances or X-rays. [return] stable isotope – an atom for which no radioactive decay has ever been experimentally measured. X-rays – electromagnetic radiation with a wavelength ranging from 0.01 to 10 nanometers— shorter than those of UV rays and typically longer than those of gamma rays. [return] References 66. J. Peterson, McDonell, M., Haroun, L., Monette, F., Hildebrand, R.D., and Taboas, A. Radiological and Chemical Fact Sheets to Support Health Risk Analyses for Contaminated Areas. Prepared by Argonne National Laboratory Environmental Science Division in collaboration with U.S. Department of Energy, Richland Operations Office and Chicago Operations Office. 2014 Feb. 22. http://www.remm.nlm.gov/ANL_ContaminantFactSheets_All_070418.pdf 90. W. N. Association. Radioisotopes in Medicine. World Nuclear Association. 2014 Feb. 23. http://www.world-nuclear.org/info/inf55.html 102. W. N. Association. Radioisotopes in Industry: Industrial Uses of Radioisotopes. World Nuclear Association. 2014 Feb. 24. http://www.world-nuclear.org/info/inf56.html 220. R. S. o. Chemistry. Cobalt. Royal Society of Chemistry. 2014 Feb. 26. http://www.rsc.org/chemsoc/visualelements/pages/pdf/cobalt.PDF 221. U. E. P. Agency. Cobalt. US Environmental Protection Agency. 2014 Feb. 26. http://www.epa.gov/rpdweb00/radionuclides/cobalt.html 222. A. Government. Radioactive Sources: Use, Safety And Security. Australian Government. 2014 Feb. 25. http://www.arpansa.gov.au/pubs/regulatory/security/ansto_safety_security.pdf 223. In LSF Magazine, pp. 14 (2012). 224. W. S. D. o. Health. Cobalt-60. Washington State Department of Health. 2014 Feb. 26. http://www.doh.wa.gov/Portals/1/Documents/Pubs/320-078_co60_fs.pdf 703. I. U. o. P. a. A. Chemistry. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Blackwell Scientific Publications, Oxford (1997).