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Name __________________________ Polygenic Inheritance Date _______________ Period_____ Background Characteristics that we inherit from our parents are called traits. Traits are determined by the genes that are passed to use from our parents. Genes come in pairs on chromosomes, so every person has two versions of each gene in a pair – one inherited from Dad and one from Mom. How many shades of blue or brown eye color can you detect among your classmates? You’ll probably have trouble naming all of the different shades of eye color. Eye color is an example of a single trait that is produced by a combination of many genes. Polygenic inheritance occurs when a group of gene pairs act together to produce a single trait. The combination of many genes acting together produces a wide variety for a single trait. The study of genetics is not a simple look at a single trait controlled by just one pair of genes because many human traits such as height, body build, the shape of eyes – lips – ears, and skin and hair color are controlled by groups of gene pairs. In this lab investigation, we will study two traits to determine if they are produced by polygenic inheritance. In other words, we’ll determine if several gene pairs act together to produce a single trait with a variety of phenotypes for that trait. If there is a variety in a sample population, then that trait is produced by polygenic inheritance. Part A – Fingerprint Patterns Problem: Are fingerprint patterns a trait that is controlled by polygenic inheritance? Materials: pencil, scrap paper, transparent tape, magnifiers, calculator Procedures for Part A: 1. Turn your pencil sideways and rub a thick spot of graphite onto your scrap paper. 2. Place your right index finger (tip to the first joint of your finger) in the graphite spot and rub from side to side. 3. To lift the fingerprint, place a strip of tape on your index finger covered by the graphite. Gently remove the tape and stick it in the box on the back of this lab sheet. 4. Wash your index finger. Right index fingerprint 5. There are three patterns that are found in fingerprints: whorl, arch, and loop. Use a magnifier to study your fingerprint pattern. Compare your print with the patterns below to see if you can find a whorl, arch, or loop. Circle the pattern that best matches your fingerprint. Whorls Arches Loops 6. Your teacher will take a verbal survey of the class. Record the number of people participating in the survey in the title of Data Table 1. Then record the number of participants that have each fingerprint pattern. Data Table 1 – Number of participants in class with whorls, arches, and loops. Total number of participants: ____________________ Number of Participants Number of Participants Number of Participants with Whorls with Arches with Loops Analysis and Conclusion: 1. Calculate the percentage of whorls by dividing the number of participants with whorls by the total number of participants in class. Do the same for arches and loops. % whorls ________ % arches _________ % loops _________ 2. What was the most common index fingerprint pattern in the class? 3. Whorls are found in 35% of the population, arches are found in 5% of the population, and loops are found in 65% of the population. Are the percentages you calculated for participants in your survey similar to the worldwide percentages for each type of print? Explain your answer. 4. Although the three basic fingerprint patterns are common in the population, everyone’s fingerprints are unique. Even identical twins have unique fingerprints from each other. Are fingerprints a trait that is controlled by polygenic inheritance? Justify your answer. Part B – Hand Span Problem: Your hand span is the distance from the tip of your thumb to the tip of your pinky finger when your fingers are spread as far apart as you can make them. Is your hand span a trait that is controlled by polygenic inheritance? Materials: cm ruled graph paper, calculator Procedures for Part B 1. Turn the graph paper sideways (hamburger). Measure your hand span by spreading your fingers as far apart as you are able to without hurting yourself. Place your hand on the graph paper. Each line segment on the graph paper is one centimeter. Measure your hand span to the nearest centimeter. Record the distance of your hand span here: My hand span is ____________ centimeters long. 2. To determine if there is a wide range of phenotypes for hand span, collect data from participants in the class. Scientists keep personal information in a survey confidential. To practice working like scientists, we will keep the measurement of hand span confidential. Record the measurement of your hand span next to any number on the class data table transparency on the overhead projector. Do not turn on the overhead projector until all participants have recorded their hand span. 3. Return the graph paper to your storage box. Copy the class data table. Data Table 2 – Class data on hand spans to the nearest centimeter. Participant # Hand span (cm) Participant # Hand span (cm) 1 13 2 14 3 15 4 16 5 17 6 18 7 19 8 20 9 21 10 22 11 23 12 24 Analysis and Conclusion: 1. The range of a set of data is the difference between the smallest and largest quantities. What is the range of hand spans of participants in this survey? 2. The mean of a set of data is the average. What is the average hand span of participants in this survey? 3. The median of a set of data is the number in the middle when all data has been put in order from lowest number to highest number. What is the median hand span of participants in this survey? 4. The mode is the number that occurs most often in a set of data. What is the mode of your data? 5. Based on your data, is hand span a trait that is controlled by polygenic inheritance? Justify your answer. _________________________________________________________________ _________________________________________________________________ _________________________________________________________________