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51st Annual Meeting of the Association for European Paediatric and Congenital Cardiology* LYON-FRANCE 29 March-1 April Convention Centre PRELIMINARY PROGRAMME (subject to changes) GENERAL ORGANISATION: MCO CONGRES Villa Gaby - 285 Corniche JF Kennedy - 13007 Marseille, France Tel.: +33 (0) 495 093 800 - Information: [email protected] * 51ème congrès de l’Association Européenne de Cardiologie Pédiatrique et Congénitale www.aepc.org 1 PROGRAMME OVERVIEW Wednesday March 29th 2017 Lumière Auditorium Forum 1 and 2 Level Terreaux Rhône 1 DETAILED PROGRAMME 08:00-10:30 UPDATE COURSE: INHERITED CARDIAC DISEASES (I) 08:00-08:15 Introduction Lumiere Auditorium Genetic testing in inherited heart disease 08:00 10:30 UPDATE COURSE: INHERITED CARDIAC DISEASE (I) Introduction Inherited arrhythmia syndromes and sudden cardiac death in children REGISTRATION PREVIEW CLOCKROOM 08:15-10:30 Inherited arrhythmia syndromes and sudden cardiac death in children 08:15-08:30 10:10-10:30 Epidemiology of Sudden death in Children Screening programmes for prevention of Sudden cardiac death in children LQTS: mutation and gene specific risk stratification and treatment CPVT: diagnosis and (new) treatment options for a highly malignant arrhythmia Hear hoofbeats? Think Zebras : the rare inherited arrhythmia (SQTS, Timothy syndrome, Andersen early repolarization) When to implant ICDs in inherited arrhythmias syndromes Psychosocial impact of genetic testing and cascade screening 08:30-10:30 Scientific Advisory Committee Rhône 1 10:30-11:00 COFFEE BREAK Lumiere Auditorium 11:00-13:00 UPDATE COURSE: INHERITED CARDIAC DISEASES (II) Inherited cardiomyopathies Lumiere Auditorium 11:00-11:20 12:40-13:00 How to interpret genetic screening results in inherited cardiac diseases?(General talk) Risk stratification in hypertrophic cardiomyopathy: phenotype, genotype or both Dilated cardiomyopathy in children: diagnostic work-up and treatment The role of MRI in diagnosis and risk stratification in inherited cardiomyopathies Children and adolescents with suspected myocarditis: insights from the MYKKE multi-center registry Left ventricular noncompaction: is it a distinct cardiomyopathy? 11:00-13:00 National Delegates meeting & PAC meeting Rhône 1 13:00-14:00 LUNCH-EXHIBITION AREA Forum 1 and 2 14:00-15:30 UPDATE COURSE: INHERITED CARDIAC DISEASES (III) Lumiere Auditorium 14:00-14:20 15:00-15:30 Cascade screening of inherited cardiac diseases (general review for different disease, how to organize, when to screen children testing in children (general review) Marfan syndrome The phenotype-genotype correlation in Marfan syndrome Aortic root surgery in paediatric Marfan patients: why, when and how Lecture: Genetics in Congenital Heart Disease 14:00-15:30 Educational Committee meeting Rhône 1 15:30-16:00 COFFEE BREAK-EXHIBITION AREA Forum 1 and 2 16:00-16:30 Manheimer Lecture Lumière Auditorium The History of European Pediatric Cardiology and AEPC over the years : from 1963 to 2016 16:30-18:00 Opening ceremony Lumière Auditorium 18:00-20:00 Reception-Exhibition area Forum 1 and 2 08:30-08:50 08:30 Scientific Advisory Committee meeting 08:50-09:10 09:10-09:30 09:30-09:50 09:50-10:10 10:30 11:00 11:00 13:00 BREAK UPDATE COURSE: INHERITED CARDIAC DISEASE (II) Inherited cardiomyopathies REGISTRATION PREVIEW CLOCKROOM 12:00 EXHIBITION POSTERS National Delegates meeting and Professional Advisory Committee 11:20-11:40 11:40-12:00 13:00 14:00 14:00 15:30 12:00-12:20 LUNCH UPDATE COURSE: INHERITED CARDIAC DISEASE (III) Marfan syndrome Genetics in Congenital Heart Disease REGISTRATION PREVIEW CLOCKROOM EXHIBITION POSTERS 15:30 16:00 12:20-12:40 BREAK Educational Committee meeting 14:20-15:00 16:00 16:30 16:30 18:00 18:00 20:00 10 14:20-14:40 MANHEIMER LECTURE OPENING CEREMONY 14:40.-15:00 EXHIBITION POSTERS RECEPTION REGISTRATION PREVIEW CLOCKROOM 11 PROGRAMME OVERVIEW Thursday March 30th 2017 Lumière Auditorium 08:00 09:00 Forum 1 and 2 Level Terreaux Pasteur Amphitheatre Pasteur Lounge Rhône 1 Rhône 2 Rhône 3 St Clair 3 EXHIBITION POSTERS REGISTRATION PREVIEW CLOAKROOM WG Business Meeting WG Business Meeting WG Business Meeting WG Business Meeting WG Business Meeting WG Business Meeting 09:00 10:30 BREAK 11:30 13:00 Fetal MRI in CHD - insight in fetal cardiac hemodynamics and morphology and brain development 13:30 14:00 Lecture: Rheumatic fever, early diagnosis BREAK REGISTRATION PREVIEW CLOAKROOM EXHIBITION POSTERS Impact of a congenital heart disease on neurodevelopmental outcome and daily life. State of the art: Neurodevelopmental outcome after cardiac surgery in infancy. REGISTRATION PREVIEW CLOAKROOM EXHIBITION POSTERS ABSTRACT MODERATED POSTERS Keynote Lecture: UK consortium on PAH genetics: First Results of whole genome sequencing in 1000 IPAH patients Arrhythmia challenge: Improve your ECG skills- an interactive session LUNCH The Fontan physiology: more than just the heart All about Devices in Congenital Heart Diseases intervention MODERATED POSTERS BREAK 3D printing of congenital heart diseaseCurrent progress: implementation in clinical practice and education ABSTRACT Morphological demonstration I: Morphology of ventricular septal defects BREAK Lecture: 16:00 16:30 12 ABSTRACT LUNCH 15:30 16:30 18:00 19:00 Trials in Congenital Heart Diseases Pharmacotherapy of the critically ill patient with Pulmonary Hypertension in developping countries 13:00 14:00 16:30 18:00 NURSES SCIENTIFIC SESSION AEPC BUSINESS MEETING 10:30 11:30 14:00 15:30 LYON - Convention Center - www.aepc.org Sudden Death in the Young ABSTRACT EXHIBITION POSTERS REGISTRATION PREVIEW CLOAKROOM ABSTRACT Aortic Coarctation: from Morphology to Adults JOINT SESSION AEPC-JSPCCS (Inter)national Registries on Congenital Heart Diseases NURSES ABSTRACT SESSION ABSTRACT ECMO Workshop (WG Pediatric Cardiovascular Intensive Care) JAPAN Council meeting 13 DETAILED PROGRAMME Thursday March 30th 2017 08:00-09:00 WG BUSINESS MEETING 09:00-10:30 AEPC Business meeting Pasteur Amphitheatre/ Pasteur Lounge/ Rhône 1-2-3/ St Clair 3 Pasteur Amphitheatre Nurse scientific session Rhône 2 10:30-11:30 COFFEE BREAK-VISIT EXHIBITION AND POSTERS Forum 1 and 2 11:30-13:00 Fetal MRI in Congenital Heart Diseases-insight in fetal cardiac hemodynamics and morphology and brain development Lumiere Auditorium 11:30-13:00 • Overview of fetal cardiac hemodynamics & changing hemodynamics in left sided hypoplasia • Echocardiographic and Doppler changes of fetal circulation on hyperoxygenation • Findings on cerebral MRI after hyperoxygenation • Fetal MRI for detection of morphology in Congenital Heart Diseases Trials in Congenital Heart Disease Pasteur Amphitheatre • Overview of some “landmark trials”, trial design • Use of big data approaches to analyze prospective data • Basics of Pharmacokinetics in end-stage Heart Failure and why we need to know this • Cases with end-stage HF that we treat together using web-based interactive approach 11:30-13:00 Abstracts session Pasteur Lounge 11:30-13:00 Abstracts session Rhône 1 11:30-13:00 Moderated Posters Rhône 2 11:30-13:00 Pharmacotherapy of the critically ill patient with Pulmonary Hypertension Rhône 3 • Parenteral prostacycline analogue therapy in children with PAH • Experience from GOSH on novel oral PAH • Experience from Paris on novel oral PAH therapies in the youth • Keynote Lecture: UK consortium on PAH genetics: First Results of whole genome sequencing in 1000 IPAH patients. St Clair 3 13:00-13:30 Lecture: Rheumatic fever, early diagnosis in developping countries Lumiere Auditorium Impact of a congenital heart disease on neurodevelopmental outcome and daily life 14:00-15:30 14 Forum 1 and 2 Lumiere Auditorium • State of the Art: Neurodevelopmental outcome after cardiac surgery in infancy. • The impact of cardiomyopathy on a child and its family • The impact of Congenital Heart Diseases on a family’s life • Talk from the French parents organization The Fontan physiology: more than just the heart 14:00-15:30 All Rhône 1 14:00-15:30 3D printing of congenital heart disease Current progress: implementation in clinical practice and education Rhône 2 • Getting ready for 3D printing: Image acquisition • Processing of the images-Segmentation of echo, CT and MRI • 3D printing for interventional planning • 3D printing for surgical planning • 3D printing for education of patients with Congenital Heart Diseases • 3D printing for teaching clinicians; summary AEPC junior Grant 2015 14:00-15:30 Abstracts session Rhône 3 14:00-15:30 Morphological Demonstration (I): St Clair 3 • Morphology of ventricular septal defects 15:30-16:30 COFFEE BREAK-VISIT EXHIBITION AND POSTERS Forum 1 and 2 16:00-16:30 Lecture: Sudden Death in the Young Pasteur Amphitheatre 16:30-18:00 Abstracts session Lumiere Auditorium 16:30-18:00 Abstracts session Pasteur Amphitheatre 16:30-18:00 Aortic Coarctation: from Morphology to Adults Pasteur Lounge • Patho-Anatomy • Associated Syndromes • Imaging or Imagining the Aorta: From fetus to 3D • Outcome • Complex Aortic coarctation: re-Coarctation and Hybrid approach JOINT SESSION AEPC-JSPCCS: (Inter)national Registries on Congenital Rhône 1 Heart Diseases • Japan Congenital Cardio-Vascular Surgery Database: Yasutaka Hirata, Tokyo University • Japan Pediatric Interventional Cardiology Data Base: 16:30-18:00 Arrhythmia challenge: Improve your ECG skills, an interactive session 14:00-15:30 Moderated posters 11:30-13:00 13:00-14:00LUNCH 14:00-15:30 Pasteur Amphitheatre • case report about hepatic problems • case report about hepatic problems • The point of view of the hepatologist: pathophysiology of liver failure • Fontan study-VALDIG consortium from the European association for the study of the Liver (EASL) Sung-Hae, Kim Shizuoka Children’s or Ryo Inuzuka, Tokyo University • Genetic and epidemiological study in Japan: Hiroyuki Yamagishi, Keio University • Registry for rare children’s heart diseases: Fukiko Ichida, Toyama University • Database for adult congenital heart disease: Isao Shiraishi, National Cerebral and Cardiovascular Center 16:30-18:00 Nurses abstracts session Rhône 2 16:30-18:00 Abstracts session Rhône 3 16:30-18:00 ECMO Workshop (WG Pediatric Cardiovascular Intensive Care) St Clair 3 18:00-19:00 JAPAN Council meeting Level Terreaux about Devices in Congenital Heart Diseases intervention Pasteur Lounge • Are all ASD devices equal?-how to decide what to implant • Absorbable and drug eluting stents useful in CHD - What is on the horizon ? • Challenging PDA - Device options in the preterm and in the elderly • Stenting Aortic Coarctation in infancy - are there limits in times of breaking stents 15 Friday March 31st 2017 Lumière Auditorium Forum 1 and 2 PROGRAMME OVERVIEW Level Terreaux 08:00 09:00 EXHIBITION POSTERS 09:00 10:30 Ventricular ectopy as a pediatric Problem 10:30 11:30 11:30 13:00 AEPC / PACES debates EXHIBITION POSTERS REGISTRATION PREVIEW CLOAKROOM 13:00 14:00 LUNCH 14:00 15:30 REGISTRATION PREVIEW CLOAKROOM 16:30 18:00 Pasteur Amphitheatre Pasteur Lounge Rhône 1 Rhône 2 Rhône 3 St Clair 3 WG Business Meeting WG Business Meeting WG Business Meeting WG Business Meeting WG Business Meeting WG Business Meeting Joint session AEPC-JSPCCS Part I: From borderline Left Ventricle to Hypoplastic Left Heart Syndrome 3D/4D Imaging – Novel developments and clinical application ABSTRACT YOUNG INVESTIGATORS AWARDS Postoperative issues in the cardiac pediatric intensive care unit NURSES SCIENTIFIC SESSION Nutrition and the heart Physical activity and the heart BREAK Malposition of Great Arteries - fetal diagnosis EXHIBITION POSTERS 15:30 16:30 16 REGISTRATION PREVIEW CLOAKROOM LYON - Convention Center - www.aepc.org BREAK Joint session AEPC-JSPCCS Part II: From borderline Left Ventricle to Hypoplastic Left Heart Syndrome ABSTRACT ABSTRACT 13:00-13:30 State of the Art: Follow-up of devices and stents after catheter interventions JOINT SESSION CANADA Novelties and future of pacemakers in children and patients with congenital heart disease : Interactive sessions / Clinical cases Imaging the RV-PA Unit in Volume and Pressure Overload LUNCH WG SS/JS MODERATED POSTERS BREAK ABSTRACT EXHIBITION POSTERS REGISTRATION PREVIEW CLOAKROOM MODERATED POSTERS Congenitally Corrected Transposition of Great Arteries ABSTRACT Morphological demonstration I: Morphology of hypoplastic left heart and endocardial fibro-elastosis BREAK ABSTRACT Double Outlet Right Ventricle Spectrum (DORV) AEPC-TURKISH Society Tetralogy of Fallot NURSES MODERATED POSTERS ABSTRACT 17 DETAILED PROGRAMME Friday March 31st 2017 08:00-09:00 WG BUSINESS MEETING Pasteur Amphitheatre/ Pasteur Lounge/ Rhône 1-2-3/ St Clair 3 09:00-10:30 Ventricular ectopy as a pediatric Problem • Ventricular ectopy in children with a normal heart • Ventricular ectopy as a risk marker in CHD and cardiomyopathies • Ventricular ectopy in chanellopathies • Ventricular ectopy in chanellopathies Lumiere Auditorium Pasteur Amphitheatre 09:00-10:30 3D/4D Imaging-Novel developments and clinical application Pasteur Lounge 09:00-10:30 • 3D Echocardiography-current application in clinical practice • 4D Flow MRI and its clinical utility • Myocardial strain imaging-from 2D to 3D • 3D rotational angioCT Nutrition and Physical activity, and the heart: Rhône 1&2 • Dyslipidemias-what pediatric cardiologists have to know • Healthy nutrition-actual recommendations in youth Physical activity and the Heart 09:00-10:30 Abstracts session Rhône 3 09:00-10:30 Young Investigators Awards St Clair 3 10:30-11:30 COFFEE BREAK-VISIT EXHIBITION AND POSTERS 11:30-13:00 AEPC/PACES debates • Do we need invasive electrophysiology study for risk assessment in pediatric or GUCH patients? - Pro/Contra • You should use cryoenergy for every AVNRT ablation in pediatric patients. - Pro/Contra 11:30-13:00 Joint session AEPC-JSPCCS Part II: From borderline Left Ventricle to Hypoplastic Left Heart Syndrome Pasteur Amphitheatre - Neonatal Aortic stenosis with borderline LV, managed by initial balloon, leading up to Ross - Neonatal Aortic stenosis with borderline LV, biventricular repair: poor outcome - Neonatal Aortic stenosis with borderline LV, biventricular repair, good outcome - Neonatal Aortic stenosis with borderline LV, initial single ventricle palliation, later biventricular conversion Outcome and prognosis of borderline LV • Mitral valve: when to decide for biventricular repair ? • Surgical treatment of endocardial fibro-elastosis • Pulmonary pressure and vascular resistance in obstructive left heart • Univentricular repair : evaluation of right ventricle long-term outcome 11:30-13:00 Abstracts session Pasteur Lounge 11:30-13:00 Abstracts session Rhône 1 11:30-13:00 Moderated Posters Rhône 2 11:30-13:00 Postoperative issues in the Cardiac Pediatric Intensive Care Unit Rhône 3 11:30-13:00 18 Lumiere Auditorium • Key Note Lecture-Spectrum between neonatal AS and HLHS-Medical Views • Key Note Lecture-Spectrum between neonatal AS and HLHS-“Surgical Views • Management of Complex Cases-Interactive Session/Experts panel 11:30-13:00 Forum 1 and 2 • Hemondynamic monitoring in the pediatric cardiac ICU in the modern area • Biomarkers in the pediatric cardiac ICU : LCOS versus myocardial dysfunction • Inflammatory response triggered by cardio-pulmonary bypass in the pediatric cardiac ICU • Postoperative pitfalls in single ventricle patients Nurse scientific session Forum 1 and 2 Lumiere Auditorium Join Session with Canadian Society: Novelties and future of pacemakers in children and patients with congenital heart disease Pasteur Amphitheatre 14:00-15:30 Imaging the RV-PA Unit in Volume and Pressure Overload Pasteur Lounge • Challenges for prenatal diagnosis of complex MGA with unbalanced ventricles and outflow tract obstruction • Prenatal assessment of prognosis in complex MGA • Can prenatal imaging detect coronary artery distribution in fetus with TGA? • Impact of prenatal detection of complex MGA on postnatal surgical strategy: REV versus Nikaido versus aortic rotation (translocation) Interactive sessions / Clinical cases: • Lead-less pacing and defibrillators in the pediatric population and in patients with congenital heart disease • Defibrillation threshold in pediatric patients, a necessity? • Endovenous pacing in pediatric patients, when to consider, age? weight? never? • Resynchronization therapy in patients with congenital heart disease, where do we stand in 2017? • Physical activity and sports in prevention – how much, how often, how intense? • Preparticipation screening in youth- actual AEPC recommendations • Physical activity, recreation sports and exercise training in pediatric patients with CHD Pasteur Lounge Malposition of Great Arteries-Fetal diagnosis) 14:00-15:30 Nutrition and the Heart • Eating habits and their impact on metabolism and cardiovascular risk 13:00-14:00LUNCH 14:00-15:30 Joint session AEPC-JSPCCS Part I: From borderline Left Ventricle to Hypoplastic Left Heart Syndrome State of the Art: Follow-up of devices and stents after catheter interventions 09:00-10:30 13:00-13:30 • ECHO outcome variables in pediatric Pulmonary Hypertension • New useful echo variables and normal reference values • New useful MRI variables and normal reference values • Assessment of Pulmonary Vascular Resistance using XMRI technology 14:00-15:30 Moderated Posters Rhône 1 14:00-15:30 Congenitally Corrected Transposition of Great Arteries Rhône 2 • The natural history of isolated ccTGA. • When to band the PA in patients with ccTGA? • Late outcome after the double switch operation. • Electrical therapies for the failing systemic RV in ccTGA. 14:00-15:30 Abstracts session Rhône 3 14:00-15:30 Morphological demonstration: Morphology of hypoplastic left heart and endocardial fibro-elastosis St Clair 3 15:30-16:30 COFFEE BREAK-VISIT EXHIBITION AND POSTERS Forum 1 and 2 16.30-18.00 Abstracts session Lumiere Auditorium 16:30-18:00 Abstracts session Pasteur Amphitheatre 16:30-18:00 Double Outlet Right Ventricle Spectrum (DORV) Pasteur Lounge 16:30-18:00 Join Session with Turkish Society- Tetralogy of Fallot Rhône 1 16:30-18:00 Nurses Moderated Posters session Abstracts session Rhône 2 • Morphological spectrum of DORV • Imaging DORV - what do surgeons need? • 3-D printing & strategic surgical planning practical examples • Surgical indications and related technical options - VSD and Fallot type - TGA type - “Unusual” DORVs - non committed VSDs and DORV and AVSD • Challenging cases presentation, open discussion - Case one-DORV with difficult tunnelling VSDs - Case two-DORV and TGA physiology 16:30-18:00 Rhône 3 St Clair 3 19 PROGRAMME OVERVIEW Saturday April 1st 2017 Forum 2 Level Terreaux Pasteur Amphitheatre Pasteur Lounge LYON - Convention Center - www.aepc.org Rhône 1 Rhône 2 Rhône 3 08:00 09:00 09:00 10:30 INDUSTRY MEETING EXHIBITION POSTERS REGISTRATION PREVIEW CLOAKROOM 10:30 11:00 11:00 12:30 12:30 13:00 20 Rhône 4 Preparing and preserving the right heart for life Infective endocarditis in Congenital Heart Disease Failure and successes session toghether with Gerd Hausdorf lecture: cases from all over Europe Gerd Hausdorf lecture: Errors in the cath lab - how to improve patient safety NURSES SCIENTIFIC SESSION Congenital Atrio-Ventricular Valves anomalies Puzzle the experts / Fetal cases Imaging debates NURSES SCIENTIFIC SESSION Puzzle the experts: systemic disorders BREAK EXHIBITION POSTERS REGISTRATION PREVIEW CLOAKROOM Congenital coronary artenry anomalies KEYNOTE LECTURE AND CLOSURE OF THE MEETING 21 Saturday April 1st 2017 DETAILED PROGRAMME 09:00-10:30 Preparing and preserving the right heart for life Pasteur Amphitheatre • Prenatal intervention to promote right ventricular growth • How to score the small RV/PA for primary interventional or surgical RVOT-opening • Ballooning versus stenting the RVOT in neonates - what to expect on the long run • Strategies in multifocal lung perfusion • Surgical options to prepare the RV for the long run 09:00-10:30 Infective endocarditis in Congenital Heart Disease • Infective endocarditis on transcatheter pulmonary valves • Multimodality imaging of Infective endocarditis in Congenital Heart Diseases: Pasteur Lounge PET CT performance and diagnosis accuracy • Early surgery in infective endicarditis : conservative techniques • Mechanisms and pathogenesis of infective endocarditis 09:00-10:30 Failure and successes session Rhône 1 • Cases from all over Europe • Gerd Hausdorf lecture: Errors in the cath lab - how to improve patient safety 09:00-10:30 Nurses Scientific session Rhône 2 09:00-10:30 Congenital Atrio-Ventricular Valves anomalies Rhône 3 • Imaging modalities for preoperative assessment of congenital mitral valve anomaly • Shone complex: conservative surgical management of mitral valve, valve growth and long-term outcome • Ebstein valve anomaly : the determinants of right ventricle function • Individualized Surgical Treatments for Children with Ebstein Anomaly • Outcomes and Factors of Mortality in Fetal or Neonatal Diagnosis of Ebstein Anomaly. 10:30-11:30 COFFEE BREAK-VISIT EXHIBITION AND POSTERS 11:00-13:00 Congenital Coronary arteries anomalies Puzzle the experts/Fetal cases 11:00-13:00 Imaging debates Pasteur Lounge Rhône 1 • Debate I: Imaging of the newborn with congenital heart disease-is echocardiography all we need? • Debate II: Imaging in patients with heart failure: Is echocardiography all we need? 11:00-13:00 Nurses Scientific session Rhône 2 11:00-13:00 Puzzle the experts: systemic disorders Rhône 3 13:00-13:30 22 Pasteur Amphitheatre • Coronary artery arrising from the opposite sinus : diagnostic issues and risk stratification • Surgical techniques for intramural trajets in anomalous coronary arteries arrising from opposite sinus • Intramural coronary artery associated with transposition of great arteries: preoperative diagnosis and prognosis • Assessment, management and prognosis of coronary fistulae in pulmonary atresia and intac interventricular septum 11:00-13:00 Forum 1 and 2 • Neuromuscular • Oncologic • Storage diseases Keynote Lecture and closure of the Meeting Pasteur Amphitheatre 23