Download AP Biology Unit 5 – The Cell Cycle, Cell Division, Cell Signaling

AP Biology Unit 5 – The Cell Cycle, Cell Division, Cell Signaling
Name____________________________________ Block ____ Date______________________
Timeline: Oct 31st to Nov 18th; see calendar for no school days and mini-unit leading up to Thanksgiving
Textbook readings (Unit 5): Parts of Ch 6 (read over summer), Ch 11, 12, Sec. 40.1 and Sec. 18.5
Labs: Mitosis & Cell Cycle, flowers and fruits for next unit; Continue artificial selection lab, phenology
Essential Questions
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What are some key structures in organization of the animal body?
What factors limit cell size?
What is the structure and organization of the cytoskeleton? What are its functions in cellular life,
especially during cell division?
How does the cell cycle assure genetic continuity?
How does mitosis allow for the even distribution of genetic information to new cells?
How is the cell cycle regulated, and what happens when the cell cycle is not properly regulated?
How are external signals converted to cellular responses?
What are some common types of molecules involved in signal transduction?
How does cell signaling involving ras and p53 proteins play a role in cancer?
What is apoptosis and how is it regulated?
Monday
Oct 31
Chapter 12
reading, notes,
study guide, and
h.w. questions due
Nov 7
Quiz
On 40.1 and
chapter 12
Then Cn3D 3min
presentations
Tuesday
Nov 1
“unit 5 overview”
due in google
classroom
in class: finish
mitosis lab
A block 2nd block:
animal tissues lab
Nov 8
Chapter 11
reading, notes,
study guide, and
h.w. questions
Wednesday
Nov 2
Thursday
Nov 3
Mitosis lab due
Friday
Nov 4
Chapter 6 and 40.1
reading, notes,
study guide, and
h.w. questions;
finish up chapt 12
Tonight: optional
E.C. documentary
and Q&A see info
on google classroom
Work on Cn3D
Protein research
Nov 9
Nov 10
Nov 11
Parent-Teacher
conferences
No school
Veteran’s Day
No School
Signal transduction
POGIL
3 Bozeman videos:
G block 2nd block:
animal tissues lab
Begin signal
transduction group
mini-posters
Signal transmission,
Evolutionary significance
of cell signaling, Effects
of changes in signaling
pathways
Nov 14
Nov 15
Nov 16
Nov 17
Nov 18
Chapter section
18.5 notes, vocab,
study guide
Finish up all notes,
study guide, vocab,
signal transduction
mini-posters
Present signal
transduction miniposters
Review for test
Unit 5 Test
A block Lab: Flowers
& Fruits
Nov 21
Global warming
mini unit
Nov 22
Guest speaker
Ms. Appel
Nov 23
Half day;
Flowers and fruits
lab due
G block Lab: Flowers
& Fruits
Nov 24
Thanksgiving
No School
Nov 25
No school
Unit Outline
I.
II.
Animal Form and Function
a. Organs and Organ Systems
b. Tissue Types
The Cell Cycle
a. Why are cells small?
b. Prokaryotes vs. eukaryotes
c. Chromosome structure
d. Mitosis and cytokinesis
III.
e. Regulation of the cell cycle
Cell Signalling
a. Regulation of the cell cycle
b. Review of DNAàRNAàprotein
c. Cancer and the cell cycle
d. Apoptosis
The “Big Ideas” of AP Biology: In each unit, consider how these themes relate to what you learn.
1 - The process of Evolution drives the diversity and unity of life
2 - Biological systems utilize free energy and molecular building blocks to grow and to maintain dynamic homeostasis
3 - Living systems store, retrieve, transmit and respond to information essential to life
4 - Biologic systems interact, and these systems and their interactions possess complex properties
Chapter 6: A Tour of the Cell
1. Why are cells small?
2. Briefly describe the structure and functions of the cytoskeleton, with focus on its role in cell division.
Chapter 40.1. – Animal form and function
1. What are constraints on animal size and shape?
2. What are some general roles of interstitial fluid?
3. How is the body organized? What are the main functions of the organ systems of mammals?
4. What are the four different types of animal body tissues?
Chapter 12: The Cell Cycle
1. Describe the functions of cell division.
2. Using a typical animal cell as an example, describe the complete cell cycle, including all of the stages of interphase,
mitosis, and cytokinesis.
3. Compare and contrast the cell cycle in plants and animals. In prokaryotes and eukaryotes.
4. Briefly describe the regulation of the cell cycle in terms of the three cell cycle checkpoints including the roles of
cyclins and Cdks (ex. MPF)
5. Describe what happens when the cell cycle is not properly regulated.
Chapter 11: Cell Communication
1. What are uses of local and long-distance signaling between cells in prokaryotes? In eukaryotes?
2. What is an example of a plant hormone? An animal hormone?
3. Describe the three stages of cell signaling.
4. How does testosterone activate cells? [Note: this is a model that we can generalize, since many cell signals result in
activating or inhibiting transcription of specific genes.]
5. Detail the function of G protein-coupled receptors, receptor tyrosine kinases, and ion channel receptors
6. What are protein kinases? Describe the effects of a signal transduction cascade (shown in Fig. 11.9)
7. What are the roles of second messengers like cAMP, calcium ions, and IP3?
8. Describe how cell signals initiate nuclear and cytoplasmic responses.
9. What is apoptosis? Why do organisms need this process?
Section 18.5: Cancer
Study Guide: Interactive Q’s 18.9, Multiple Choice 9, 10, 11, 13, 21
1. What is the role of viruses in cancer?
2. What are oncogenes and how are they related to proto-oncogenes?
3. How do mutations in the ras gene contribute to cancer? What kind of protein is encoded by ras?
4. How do mutations in p53 gene contribute to cancer? What kind of protein is encoded by p53?
5. What is meant by the multistep model of cancer development?
6. How does genetics contribute to cancer?