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DNA • DNA stands for Deoxyribonucleic Acid and is found in structures called chromosomes in the nucleus of cells. • Chromosomes are made of both proteins and nucleic acids, and when a cell is not dividing they are stored as a spaghetti like tangle called chromatin. • DNA directs everything a cell does and is the code that dictates what proteins a cell makes • DNA structure: a twisted ladder made of two strands of nucleotides connected by hydrogen bonds between the nitrogen bases of the opposite nucleotides (these make the “rungs” of the ladder) • The nitrogen base parings in DNA are always: o Thymine + Adenine o Guanine + Cytosine Steps in DNA Replication • For a cell to replicate the DNA must first double itself by: unwinding, splitting in half, and then duplicating. 1. DNA unwinds 2. Hydrogen bonds between nitrogen bases break and DNA “unzips” 3. New nucleotides (from the food we eat) are added to each side of the now unzipped DNA by an enzyme called DNA polymerase 4. Two complete DNA ladders now exist where only one did before (each one is half the old strand, and half new) This is called semi conservative replication