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Science and Music? "Imagination is more important than knowledge." What is Central Dogma? + = ??? DNA RNA Protein DNA = RNA = RNA Polymerase = Proteins = Ribosome = Are you ready for… Featuring… Double-Stranded DNA Transcribed by a Polymerase Makes single-stranded RNA To get proteins when translated DNA is fantastic Deoxyribonucleic acid On the sugar ribose It has one hydroxyl It’s negatively charged on the phosphate backbone HO Four nucleotide bases seen There’s Guanine and Cytosine And Adenine and there’s Thymine They Hydrogen bond- AT two, CG three AG is pure so they’re purines, and they also got these two rings CT are pyrimidines Primitive, They only have one ring = You got… If that’s the template strand, Then what is the complementary strand? = It’s…. 3’ 5’ 5’ 3’ Double-Stranded DNA Transcribed by a Polymerase Makes single-stranded RNA To get proteins when translated RNA is fantastic It’s ribonucleic acid On the sugar ribose it has two hydroxyl It’s negatively charged on the phosphate backbone Four nucleotide bases seen It’s like DNA , but no thymine It’s uracil, know what I mean? The only difference is that it’s got no CH3 = RNA Polymerase Runs to prime on DNA Making to prime of RNA: messenger, transfer, ribosomal hey~ RNAP runs 3’ 5’ RNA synthesized 5’3’ Double-Stranded DNA Transcribed by a Polymerase Makes single-stranded RNA To get proteins when translated Proteins are fantastic It’s made of 20 amino acids Some of their side-chains have a hydroxyl One end is amino and the other is carboxyl Ribosomes are actually made Of proteins and rRNA They have ability to translate Whatever is on the mRNAs Into proteins proteins But what’s the coding? Three nucleotide sequences corresponding To amino acids see? IF AUG is start then let’s A-U-G Double-Stranded DNA Transcribed by a Polymerase Makes single-stranded RNA To get proteins when translated Double-Stranded _____ DNA ________ by a ________ Transcribed Polymerase Makes single-stranded RNA ____ translated proteins when ________ To get _______ DNA is fantastic ____________________ Deoxyribonucleic acid one On the sugar ribose It has ___ hydroxyl It’s _________ charged on the negatively phosphate backbone Four nucleotide bases seen There’s _______ Guanineand _______ Cytosine Thymine AndAdenine ______ and there’s ______ They Hydrogen bond- AT ___,2 CG ___3 RNA is fantastic It’s _____________ Ribonucleic acid two On the sugar ribose it has ___ hydroxyl It’s negatively charged on the Phosphate _____________ backbone Which one of these do not belong in RNA? RNA Polymerase Runs 3 to 5 prime on DNA Making 5 to 3 prime of RNA: ___________, ________, Messenger Ribosomal hey~ Transfer _________ What do you get when you throw an atomic bomb into the ocean? A nucleo-TIDE True or False? The Central Dogma is always true Which came first? Protein or RNA? Science and Creativity • • “To invent, you need a good imagination and a pile of junk.” -Thomas A. Edison "The important thing is not to stop questioning. Curiosity has its own reason for existing.” –Albert Einstein SUMMARY: Double-Stranded DNA Transcribed by a Polymerase Makes single-stranded RNA To get proteins when translated Thank You!!!
