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Names ____________________________ ____________________________ Cancer Project Goal: Research a specific type of cancer and apply the information you have learned to determine the appropriate mechanism of inheritance and how the cancer affects the cell cycle. Key facts from the WHO Cancer Webpage: ● ● ● ● ● ● ● ● ● Cancers figure among the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer related deaths in 2012. The number of new cases is expected to rise by about 70% over the next 2 decades. Among men, the 5 most common sites of cancer diagnosed in 2012 were lung, prostate, colorectum, stomach, and liver cancer. Among women the 5 most common sites diagnosed were breast, colorectum, lung, cervix, and stomach cancer. Around one third of cancer deaths are due to the 5 leading behavioral and dietary risks: high body mass index, low fruit and vegetable intake, lack of physical activity, tobacco use, alcohol use. Tobacco use is the most important risk factor for cancer causing around 20% of global cancer deaths and around 70% of global lung cancer deaths. Cancer causing viral infections such as HBV/HCV and HPV are responsible for up to 20% of cancer deaths in low- and middle-income countries. More than 60% of world’s total new annual cases occur in Africa, Asia and Central and South America. These regions account for 70% of the world’s cancer deaths. It is expected that annual cancer cases will rise from 14 million in 2012 to 22 within the next 2 decades. Cancers to Choose From: See Attached list from cancer.gov Your Job: 1. Choose a type of cancer to study. 2. Research your cancer to determine: a. What happens in the body to allow the cancer that you chose to form. b. What environmental factors may cause the cancer that you chose to begin to form or impact its growth. c. Whether the cancer that you chose can be inherited, if so explain how it is transmitted, and how this causes the cancer to be more likely to form. d. What the cancer does to the body as it grows. e. How this particular cancer is treated currently, and how is this treatment different from the way that other cancers are treated? 3. You will present your project to the class in one of the following formats: a. Prezi b. PowerPoint c. Tri-Fold Poster d. ask your teacher if you have a better idea for a presentation Final Due Date: ____Tuesday, December 13____ Rubric for Grading Criteria 0 points Type of Cancer The student didn’t turn in the project or attempted to explain cancer in general terms without picking a type of cancer to research Methods used to treat your cancer specifically How does cancer chosen start in the body? List of Environmental Hazards that can Lead to Cancer Not addressed Not addressed Not Addressed 1 Point 2 points 3 points 4 points The student clearly picked a single type of cancer to study. Listed several methods Listed several currently used to treat Listed methods, methods currently cancer chosen, and but methods were used to treat explain why they were not specific to specific type of used and what they did type of cancer cancer but did not to the cancer and to the chosen describe what the health of the person methods actually who would be using the did methods The written The written explanation explanation includes three of the includes one of four important pieces The written the four important information. explanation pieces includes two of the information. four important pieces information. The student has highlighted the specific environmental The student has hazards that can generated a list of lead to the cancer environmental that they have hazards that can chosen specifically lead to cancer, but does not If no clear specify which lead connection can be to their cancer made to chosen environmental hazards at this time, the student has indicated this but does not cite a source to support this The student has highlighted the specific environmental hazards that can lead to the cancer that they have chosen and the student explains how these environmental hazards impact the checkpoints or genes that control the cell cycle. If no clear connection can be made to environmental hazards at this time, the student has indicated this and cited a source to support their statement. This explanation clearly includes: The events of the cell cycle, the purpose of each checkpoint, and the potential impact of replication errors on the cell cycle, and a discussion concerning how changing genes can induce cancer in a cell. Inheriting Cancer Inheriting Cancer & The Cell Cycle Not Addressed Not Addressed The student has a The student has a written explanation for written explanation how cancers, or the for how cancers, tendency to get cancer, or the tendency to can be inherited. get cancer, can be Student also indicates inherited. Student The student has a The student has a in their explanation also indicates in general written general written what the risk of their explanation explanation for explanation for inheriting the cancer of what the risk of how cancers, or how cancers, or choice/risk of inheriting inheriting the the tendency to the tendency to an increased chance of cancer of get cancer, can get cancer, can be getting the cancer of choice/risk of be inherited, but inherited. Student choice is. inheriting an does not apply includes brief increased chance the information to explanation Student includes the of getting the the cancer that indicating the risk gene suspected to be cancer of choice is. they have chosen of inheriting the influencing the to research. cancer of choice. tendency to get their Student includes chosen cancer, but the gene Student does not does not include its suspected to be include the gene inheritance pattern. influencing the suspected to be tendency to get influencing the If no clear connection their chosen tendency to get can be made to genetic cancer, and its their chosen inheritance at this time, inheritance pattern. cancer or its the student has inheritance pattern indicated this and but If no clear did not cite any sources connection can be to support their made to genetic statement. inheritance at this time, the student has indicated this and cited a source to support their statement. The student has a The student has a written explanation written explanation for for how inheriting how inheriting a The student has a a tendency to get tendency to get cancer written explanation The student has a cancer can make can make cancer more for how inheriting a brief written cancer more likely likely to form (explain tendency to get explanation for to form (explain this on the molecular cancer can make how inheriting a this on the level of genes and cancer more likely tendency to get molecular level of checkpoints). to form (explain cancer can make genes and this on the cancer more likely checkpoints). The explanation is molecular level of to form in general missing the discussion genes and terms. The explanation is of any malformed or checkpoints). missing the missing proteins that discussion on any may impact the The explanation malformed or checkpoints, and/or the includes a missing proteins genes associated with discussion of any that impact the those proteins. malformed/missing checkpoints, and proteins that may the genes impact the associated with checkpoints, and those proteins the genes associated with those proteins. What does cancer do to a body Not addressed Lists symptoms only without explanation for how those symptoms might arise Not addressed Indicates the likelihood of metastasis of this cancer, and what will happen to the cancer and the body in the event of metastasis, including the most likely organs to be affected by this event Not addressed Indicates that there are new treatments and may describe them in general terms (ex: there is Indicates at least a new 1-2 new chemotherapy), treatments and but does not describes what indicate precisely makes them up what the new and how they treatments are or specifically impact do to the the cancer while body/cancer reducing the impact on the Says that the body. cancer is reduced and the body is not harmed as much by the new treatment (in that general form) Indicates that metastasis could happen Metastasis New methods for treating a cancer There are either parenthetical citations within the presentation or a works cited page. Citations Lists symptoms and indicates who the cancer physically changed the body and caused those symptoms to occur for at least 2 symptoms. Nothing is cited There are properly used parenthetical citations and a properly formatted If both are works cited page. present, there are All necessary substantial material (including mistakes in paraphrased formatting on the material) is cited works cited page properly, or there are many missing parenthetical citations. Presentation: Visual Aids Not present Presentation: Legibility Illegible on more than one slide make sense with don’t make sense the content of the with the content of presentation and the presentation is visually appealing illegible on only one slide, or print is difficult to read from a distance, but still legible student read some information off of the PowerPoint, but not all Presentation: Speaking student read off of the PowerPoint for the whole presentation Presentation: Eye Contact student occasionally student never looked at the looked at the audience, but not audience for most of the presentation legible from a distance, all print is easy to read student didn’t read off of the PowerPoint, (note cards are acceptable) and included information that could not be found on just the PowerPoint alone student looked at the audience for most of the presentation Total Points Received: ______________________________________ /35 Works Cited "Cancer." WHO. N.p., Feb. 2015. Web. 20 Aug. 2015. "Cancer Types." National Cancer Institute. N.p., n.d. Web. 25 Sept. 2015.