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INDEX Acids, poiy-a-amino, antigenicity of, 381, 388, 393 Actinophage, antibody to, 782 Adrenals, response to sound stress, 17 Adsorption of native antigen, 444 A2G mice, resistance to myxoviruses, 942 Agglutination, leukocyte, 628 - - , mixed, demonstration of human measles antibody by, 908 --of human erythrocytes reacting in immuneadherence, 86 Amnion cell culture, panereatin procedure for, 956 Anaphylaetic reaction, effect of excess antigen on, 165 Anaphylaxis, cutaneous, 43 Antibacterial action of human saliva, 12 --defense, effect of radiation injury on phagocytic mechanisms of, 914 Antibodies, "cell-fixed" to tuberculin purified protein derivative, 52 - - , chicken, temporal synthesis and chromatographic and ultracentrifugal characteristics of, 399 - - , immunologic specificity to liver ribosomes and nuclei, 416 - - , insulin binding, in human sera, 760 - - , liver localizing, 424 - - , measles and poliovirus, in human 7-globulin, 81 - - , micromethods for study of, 741 - - , opsonizing, in typhus, 127 - - , purified, from individual rabbits, 318 , , sensitizing properties of, 810 - - , salicylate, detection of, 788 Antibody activity in 7-, ~ - and ~2M-globulins, 760 - - , combination with factor other than NADase, 793 - - , staphylococcal, in germfree mice, 358 Antibody detection by isotope techniques, 829 determinations, production and effect, 793 excess, formation of soluble complexes in region of, 935 formation and phagocytosis, 228 - - - - in primary response, 60 - - , human measles, by mixed agglutination, 908 - - i n d u c i n g and anaphylactogenic properties of Bordetella pertussis cells and Freund's adjuvant, 132 - - , isolation of, 347 - - , p r e c i p i t a t i n g , mitosis and maturation in formation of, 897 - - , preparation and use of erythrocytes for detection of, 741 -producing cells, absence during unresponsiveness to BSA, 478 by chicken spleen cells, 829, 836 - - - - - - - - - - p r o d u c t i o n single cells, 952 - - - - splenic tissues, 672 - - , effect of methotrexate on, 324 thymectomy and bursectomy on, 878 - - , ribonucleoprotein-bound, 734 - - to actinophage, 782 Antigen-antibody complex, coagulated, immunochemistry of, 438, 444 - - - - - i n t e r a c t i o n , test for, 619 - - d o s a g e , role in drug-induced immunologic tolerance, 703 excess, effect on anaphylactic reaction, 165 - - i n certain strains of group A streptococci, properties, 595 - - , native, adsorption and subsequent desorption, 444 - - , preparation and use of erythrocytes for detection of, 741 - - , radioactive, cellular localization in, 561 - - , soluble, effect of bis-diazo benzidine and tannic acid treatment on sensitization by, 663 , , soluble, from Bordetella pertussis, 72 - - , viral and infectious virus in HeLa cells infected with reovirus, 548 Antigenic analysis of poliovirus, 280 of oral poliovaccine progeny, 288 - - f a c t o r s of cattle erythrocytes, 857 , variation in reactivity of, 857 Antigenicity testing of Salk vaccine, 193 ~ , comparison to antibodies produced in individual rabbits, 318 obtained by fractionation of Coxsackie viruses, serologic reactivity of, 654 - - , soh~ble, competition, 685 - - , streptococcal and tissue, 595 - - , type A S, specificity of, 172 Antiglobulins in normal serum, 238 Antihistamine, relative insusceptibility of cutaneous anaphylaxis to, 43 Antl-ovalbumin specificity of lymph node cells in delayed type hypersensitivity, 337 Anti-Rh~(D), sialic acid specificity of, 518 Anti-S serum, production, 172 Antisera, fluorescent, purification of, 634 - - , sensitizing properties of, 810 - - , sheep, neutralization of visna virus by, 185 - - , specificity to mouse ascites tumor, 24 Antitoxin, diphtheria, disk plate assay for, 201 Arbesman, Carl E., 612, 760 Arboviruses, group A, cross-protection among, 720 Argyris, Bertie F., 29 Arquitla, Edward R., 843 - - - - - - - - - - c h a r a c t e r i z a t i o n - - 971 972 INDEX Arthritis, infectious, behavior of Escherichia coli endotoxin during, 297 Asofsky, R. M., 60 Aspinall, Richard L., 872, 878 Autoantibodies to heart, cardiac lesions associated with, 725 Ayoub, Elia M., 793 Axelrod, Velma, 1 Axtell, S. L., 506 Bacillus subtilis, bactericidal property of rabbit serum for, 540 Bactericidal property of rabbit serum, 540 Bactericidin, lactobacillus, eofactor requirements, 12 Baer, Harold, 121 Baker, James A., 324 Barrett, James T., 643 Barron, Almen L., 908 Barta, George, 72 Bassett, Emmett W., 318 Batshon, Badi A., 121 Beisaw, Norman E., 532 Beiser, Sam M., 318 Bell, E. John, 770 Benacerraf, Baruz, 466, 751 Benedict, Albert A., 399 Bentonite particles, opsonic effect of complement on, 607 Benyesh-Melniek, Matilda, 280 ~2A-Globulins, 576 - - - - - , antibody activity in, 760 ~M-Globulins, antibody activity in, 760 Bigley, Nancy J., 416, 518, 526 Bis-diazo-benzidine, effect on sensitization by soluble antigen, 663 Bloomfield, Norman, 888 Boche, R. D., 506 Bonstein, Herbert S., 612 Bordetella pertussis cells and Freund's adjuvant, comparison, 132 - - - - , protective antigen from, 72 Botulinum toxoid, immunologic response to, 697 Bovine serum albumin, acquired tolerance and immune response after injection of, 217 ., unresponsiveness to, absence of antibody-producing cells during, 478 - - - - , normal, eonglutinating system in, 347 Bradley, S. Gaylen, 782 Brady, Roscoe O., 372 Braude, A. I., 297 Brown, Ronald J., 399 Buras, Netty S., 412 Bursectomy, effect on precipitin and hemagglutinin production, 878 - - - - - - survival of skin homografts, 872 Butler, William T., 663 Cabasso, V. J., 81 Campbell, Dan H., 619 Cardella, Matteo A., 697 Cardiac lesions associated with auto antibodies to heart, 725 Carruthers, E. J., 506 Cashman, Thomas, 393 Catz, Boris, 843 "Cell-fixed" antibodies to tuberculin purified protein derivative, 52 Cells, antibody producing, absence during unresponsiveness to bovine serum albumin, 478 - - , lymph node, anti-ovalbumin specificity in delayed type hypersensitivity, 337 - - , mononuclear and polymorphonuclear exudate, phagocytic and enzymatic functions, 448 - - , phagocytic host, and rickettsiae, interaction, 127 Cellular infiltrate in delayed reactions, 466 Cesium chloride density gradients, serologic reactivity of antigens obtained by fractionation of Coxsaekie viruses in, 654 Chang, Walter W. Y., 35 Cherry, William B., 358 Chin, Jean N., 548 Clarke, F. H., 81 Clostridium botulinum, immunity to toxins of, 697 Cobalt-60 irradiation and immunity to influenza virus, 506 Cohen, Jay 0., 358 Collins, Nancy M., 238 Complement components, isolation of, 347 - - - - a n d phagocytosis, 607 fixation, antigenic analysis of influenza viruses by, 172 - - , measurements by agglutination of human erythroeytes in immune adherence, 86 - - , role in immune clearance of Escherichia coli and rat erythrocytes, 751 Complex, antigen-antibody, immunoehemistry of, 438, 444 Complexes, soluble, formation of, 935 Conglutinin, isolation of, 347 Coons, Albert H., 478, 634 Coxsackie virus antigens, serologic reactivity of, 654 Craig, John M., 725 Craig, J. P., 43 Cremer, Natalie E., 685 Cross-protection among group A arboviruses, 720 - - Dameshek, William, 703 Daniel, Thomas M., 741 Dannenberg, Arthur M., Jr., 448 Datta, S. P., 857 Davidsohn, I., 584 DEAE chromatography, fluorescein-labeled ~globulins purified by, 116 INDEX 973 Dennis, Juanita, 654 Dermacentor andersoni, rickettsias isolated from, 770 Dermacentor variabilis, rickettsias isolated from, 770 Desorption, subsequent, of native antigen, 444 de Vaux St. Cyr, C., 246, 257 de Vries, T., 60 Diphtheria antitoxin, disk plate assay for, 201 Disk neutralization test in antigenic analysis of poliovirus, 280 - - p l a t e assay for diphtheria antitoxin, 201 Distemper virus, attenuated, effect of methotrexate on production of antibodies against, 324 Diwan, Arwin R., 280, 288 Dodd, Matthew C., 416, 518, 526 Douglas, H., 297 Fish, A. J., 52 Flax, Martin H., 178 Fleming, Diane O., 914 Fluoreseein-labeled ~-globulins, 116 Formaldehyde and poliovirus, reaction in magnesium chloride solution, 429 Forster, Othmar, 935 Fraction, antigenic, responsible for formation of liver localizing antibodies, 424 Freedman, Samuel O., 52 Freund, Jules, 1890-1960, 331 Freund's adjuvant and Bordetella pertussis cells, comparison, 132 Frick, O. L., 165 Frommhagen, Laurence H., 116, 654 Fulton, Forrest, 280 Furesz, John, 193 Electrophoretic boundary disturbances, 619 Encephalomyelitis, allergic, and x-irradiation, 532 - - , Pseudomonas organisms as adjuvants in, 512 Endotoxin, effect during primary response, 60 --, Escherichia coli, behavior during infectious arthritis, 297 - - , group C meningococcal, 312 --, intraperitoneal injection, effects of, 540 Enteroviruses, susceptibility of human amnion cells to, 956 Enzymatic functions of mononuclear and polymorphonuclear exudate cells and alveolar maerophages, 448 Erythrocyte serum, effect of prolonged immunization on, 584 Erythroeytes, agglutination of, in immuneadherence, 86 - - , cattle, antigenic factors of, 857 - - , foreign, recognition, 412 - - , formalinized, hemagglutination studies with, 663 - - , persensitized, effect of ionic strength on, 925 - - , preparation and use for detection of antigen and antibody, 741 - - , role of complement in immune clearance of, 751 Escherichia coli endotoxin, behavior during infectious arthritis, 297 , role of complement in immune clearance of, 751 Eseribano, J., 257 Esterases, urinary and mouse serum, 246 - - , - - , - - rat serum, 257 Galasso, G. J., 647 -/-Globulin, aggregated, biologic activities of, 960 - - - - - allotypes, 98 - - - - - and antibody formation in vitro, 60 . . . . coated Bentonite particles, opsonic effect of complement on, 607 - - - - - , human, measles and poliovirus antibodies in, 81 - - - - - , rabbit, fragments of, 865 - - - - - , reactivity of rheumatoid arthritis sera with, 107 - - - - - , x-irradiated, specificity of, 224 ~-Globulins, 576 --~--, antibody activity in, 760 - - - - - , fluorescein-labeled, 116 Gangliosides, immunochemistry of, 372 Gauld, John R., 127 Gearinger, Naomi F., 697 Gerulat, Bernard F., 381,388 Geyer, Virginia B., 416, 518, 526 Globulin, see also ~-Globulin and fl-Globulin Goodman, Joel W., 865 Gordon, Milton, 209 Grabar, P., 246 Graetzer, Mary A., 872, 878 Grayston, J., Thomas, 849 Gregg, Michael B., 368 Gross, Dale, 865 Guthrie, Richard A., 643 Fahey, John L., 576 Farr, Richard S., 619 Farrell, Leone N., 201 Fazekas de St. Groth, S., 140, 151 Ferrebee, Joseph W:, 324 Finn, Jack, 843 Fiock, Mary A., 697 H-2 system, isoantigens of, 271 Halpern, Bernard N., 165, 810 Hapten-induced leukoagglutinin, 643 Harter, John G., 634 Hayashi, Hajime, 956 Hearn, Henry J., Jr., 720 Heart, autoantibodies to, induced by immunization with heterologous heart, 725 - - , heterologous, autoantibodies to heart induced by immunization with, 725 974 INDEX tissue, human, properties of antigen exhibiting cross-reaction with, 595 - - --, immunologic studies of, 725 HeLa cells infected with reovirus, 548 Hemagglutination studies with formalinized erythrocytes, 663 --test, tanned cell, inhibition by human cell derivatives, 888 Hemagglutinin production, effect of thymectomy and bursectomy on, 878 Hermann, G., 246, 257 Hersh, R. T., 399 Herzenberg, Leonard A., 628 Herzenberg, Leonore A., 628 Hobson, Derek, 942 Homma, J. Yuzuru, 819 Homografts, skin, survival, 872 Howes, Homer A., 788 Hunder, Gene G., 540 Hypersensitivity, delayed, and immunity in tularemia, 209 , type, anti-ovalbumin specificity of lymph node cells in, 337 --reactions, delayed, specificity of cellular infiltrate in, 466 - - to ragweed, canine, spontaneous, 35 - - Immunity and delayed hypersensitivity in tularemia, 209 --, induction in mice with pneumoeoccal polysaceharide, 929 Immunization, prolonged, effect on immunologic activity of erythrocyte serum, 584 Immunochemistry of antigen-antibody complex, 438, 444 - - of gangliosides, 372 of globulin altotypes, 98 Immunologic relation of streptococcal and tissue antigens, 595 Infectivity of ribonucleic acid prepared from influenza-infected cells, 265 Infiltrate, cellular, in delayed reactions, 466 Influenza-infected ribonucleic acid, 265 - - virus-antibody system, 140, 151 , cobalt-60 irradiation and immunity to, 506 --viruses, antigenic analysis of, 172 Insulin-binding antibodies in human sera, 760 Ionic strength, effect on persensitized erythrocytes, 925 Irradiation and anti-viral immunity, 506 Ishak, Kamel, 711 Ishizaka, Kimishige, 960 Ishizaka, Teruko, 960 Isoantigens, It-2 and non-H-2, detection, 628 --, mouse, phenotypic expression of, 271 Isotope techniques, antibody detection by, 829 Ito, Fumiko, 819 - - Jacobson, E. B., 60 Jacox, Ralph F., 540 Jankovi6, Branislav D., 178 Jensen, Marcus M., 17, 21 John, A. Charlotte, 554 Johnson, Arthur G., 672 Jones, J. L., 297 Kabat, Elvin A., 810 Kaplan, Melvin H., 595, 725 Kapral, Frank A., 448, 804 Karzon, David T., 908 Kiser, K. H., 81 Klebsiella pneumoniae type 2 polysaccharide, immunologic paralysis produced by, 121 Klein, Esther R., 24 Knight, Charles O., 548 Kochan, Ivan, 711 Kohls, Glen M., 770 Kong, Yi-Chi M., 672 Kormendy, Agnes C., 201 Krueger, Robert G., 952 L cells, serum effect on virus progeny of L cells, 647 Lackman, David B., 770 Lactobacillus bactericidin, cofactor requirements, 12 Lane, Christine A., 942 Langevoort, H. L., 60 Lazen, Alvin G., 526 Lee, C. L., 584 Lennette, Edwin H., 548, 554, 654 Lenzner, Alfred R., 760 Leon, Myron A., 347 Leonard, M. R., 228 Leskowitz, Sidney, 98 Leukoagglutinin, hapten-induced, 643 Leukocyte agglutination, 628 - - counts, peripheral, response to sound stress, 17 Leukocytes, human blood, dissociation of phagocytosis and intracellular killing of Staphylococcus aureus by, 804 Li, Isabel W., 804 Liacopoulos, Panayotis, 165, 810 Liacopoulos-Briot, Monique, 810 Lief, Florence S., 172 Lindenmann, Jean, 942 Lipid-adsorbed virus vaccines, 1 Lipton, Murray M., 512 Liver localizing antibodies, 424 --, recognition of foreign erythrocytes by, 412 --, response to sound stress, 17 Lo Grippo, Gerald A., 956 Luzzio, Anthony J., 224 Lymph node cells, anti-ovalbumin specificity in delayed type hypersensitivity, 337 INDEX 975 Obituary: Jules Freund, 1890-1960, 331 Oreskes, Irwin, 107 Ozaki, Yoshikatsu, 280, 288, 429 Panczyszyn, O., 584 Papain fragments of myeloma proteins, 576 Paralysis, immunologic, produced by Klebsiella pneumoniae type 2 polysaccharide, 121 Paterson, Philip Y., 532, 929 Patterson, Roy, 35, 829, 836 Patton, Charlotte, 711 Perkins, Eugene H., 228 Peters, John H., 634 Phagocytic functions of mononuclear and polymorphonuclear exudate cells and alveolar maerophages, 448 host cells and rickettsiae, interaction, 127 --mechanisms and radiation injury, 914 Phagocytosis and antibody formation, 228 killing of Staphylococcus aureus, dissociation, 804 --, in vitro, 448 of Bentonite particles, opsonic effect of complement on, 607 Pinchuck, Paul, 381,388 Plotz, Charles M., 107 Pneumococcal polysaecharide, response of mice to, 929 Poliomyelitis vaccine, Salk, antigenicity test for, 193 Poliovaceine progeny, antigenic characterization of, 288 Poliovirus and formaldehyde reaction in magnesium chloride solution, 429 antibodies in human -y-globulin, 81 --, antigenic analysis of, 280 Pollard, Leonard W., 634 Poly-~-amino acids, antigenicity of, 381,388, 393, 493 Polypeptides, antigenicity of, 381,388, 393, 493 Polysaccharide, pneumococcal, response of mice to, 929 PPD, "cell-fixed" antibodies to, 52 Precipitin production, effect of thymectomy and bursectomy on, 878 Pressman, David, 424, 760 Protein antigens, formation of soluble complexes with, 935 ---sensitized erythrocytes, preparation and use for detection of antigen and antibody, 741 Proteins, micromethods for study of, 741 --, purified, immunologic unresponsiveness to, in guinea pigs, 368 --, serum, aggregated products of, 960 Pruzansky, Jacob J., 35, 829 Pseudomonas aeruginosa, surface structure of, 819 Pseudomonas organisms as adjuvants in experimental allergic encephalomyelitis, 512 --polysaccharide, Rho(D) specificity of, 526 Pancreatin procedure for amnion cell culture, 956 Quilligan, J. J., Jr., 506 Maassab, Hunein F., 265 Maerophages, alveolar, 448 Mage, Michael, 318 Magnesium chloride solution, reaction of poliovirus and formaldehyde in, 429 Maier, Patricia, 760 Makinodan, T., 897 Martin, G. R., 312 Martins, Mary J., 116 Maturation in antibody synthesis, 897 Maurer, Paul H., 381, 388, 393,493 McBride, W. David, 288 McCluskey, Jean W., 466 McClnskey, Robert T., 466 McDevitt, Hugh O., 634 McDuffie, Norman M., 438, 444 McVety, Lora M., 24 Measles antibodies in human ~-globulin, 81 antibody, human, by mixed agglutination, 908 Melnick, Joseph L., 238, 429 Meningococcal endotoxin, group C, 312 Mergenhagen, S. E., 312 Metcalfe, David S., 643 Methotrexate, effect on antibody production, 324 Meyer, Roland K., 872, 878 Mieseher, P. A., 751 Milgrom, Felix, 908 Mishell, Robert I., 628 Mitosis in antibody synthesis, 897 Mitotic apparatus, role in intracellular location of reovirus antigen, 554 MSller, G6ran, 271 Mononuclear and polymorphonuclear exudate cells, phagocytic and enzymatic functions of, 448 Moreau, Pierre, 193 Mudd, Stuart, 804 Munoz, J., 132 Myeloma proteins, papain fragments of, 576 Myxoviruses, resistance of A2G mice to, 942 - - NADase, other factor, with antibody, 793 Neisseria meningitidis, endotoxin of group C, 312 Nelson, Eric L., 412 Neutralization kinetics, antigenic characterization of oral poliovaccine progeny by, 288 - - o f animal viruses, 140, 151 Newton, Walter L., 358 Nishioka, Kusuya, 86 Novelli, G. David, 734 Nuclei, immunologic specificity of antibodies to, 416 - - - - - - - 976 INDEX Radiation injury and phagocytic mechanisms, 914 Ragweed hypersensitivity, canine, spontaneous, 35 - - pollen, "purified" fraction of, 612 Rainey, Cullen T., 720 Rana pipiens, cellular demonstration of antibody production in, 952 Randles, Chester I., 526 Ransby, Arnold, 347 Rasmussen, A. F., 17, 21 Reactions, hypersensitivity, specificity of cellular infiltrate in, 466 Reid, D. B. W., 201 Reif, Arnold E., 24 Reisman, Robert E., 612, 760 Relyveld, Edgar H., 810 Reovirus antigen, 548, 554 Response, immune, after injection of bovine serum albumin, 217 --, primary, antibody formation in, 60 Reticuloendothelial system, clearance of Escherichia coli and rat erythrocytes by, 751 Rheumatoid arthritis reactions, inhibition of, 888 - - - - sera, reactivity with ~,-globulin, 107 Rho(D) specificity of Pseudomonas polysaccharide, 526 Ribonucleic acid, influenza-infected, 265 Ribonucleoprotein-bound antibody, 734 Ribosomes, liver, immunologic specificity of antibodies to, 416 Rickettsia prowazekii, opsonizing antibodies in, 127 Rickettsiae and phagocytic host cells, interaction, 127 Rickettsias from Dermacentor, 770 Rigney, Mary M., 643 Rivanol, fluorescein-labeled ~-globulins purified by, 116 Rosak, Michael, 337 Rose, Noel R., 612 Rosenblatt, Melvyn, 788 Rytel, Michael W., 607 Sage, Harvey J., 347 Salicylates, detection of humoral antibodies against, 788 Salk vaccine, rooster antigenicity test for, 193 Salv~n, S. B., 368 Schiffmann, E., 312 Schmidt, Nathalie J., 654 Schwartz, Robert S., 703 Sehon, A. H., 52 Sensitivity, skin, bronchial and anaphylactic, 35 Sensitization and acquired tolerance in mice, 217 - - by soluble antigen, effect of bis-diazo-benzidine and tannic acid treatment on, 663 Sera, human, insulin binding antibodies in, 760 --, normal human, tuberculostatie activity of, 711 --, rheumatoid arthritis, reactivity with ~--globulin, 107 Sercarz, Eli E., 478 Serum, bovine, nolanal, conglutinating system in, 347 --derivatives, human, that inhibit rheumatoid and other reactions, 888 --, effect on virus progeny of L cells, 647 --, erythrocyte, effect of prolonged immunization on, 584 --factor transferring skin, bronchial and anaphylactic sensitivity, 35 ~ , immune platelet, intravenous administration of, effects, 540 --, mouse, and urinary esterases, 246 --, normal, antiglobulins in, 238 - - proteins, rabbit, aggregated products of, 960 --, rabbit, bactericidal property of, 540 --, rat, and urinary esterases, 257 Shaffer, Morris F., 121 Sharp, D. G., 647 Sialic acid specificity of anti-Rho (D), 518 Singer, Jacques M., 107 Siskind, Gregory W., 929 Smith, Mary Ruth, 914 Sorem, Gail L., 217 Specificity, anti-ovalbumin, of lymph node cells in delayed type hypersensitivity, 337 --, immunologic, of antibodies to liver ribosomes and nuclei, 416 Speirs, E. E., 561 Speirs, R. S., 561 Spendlove, Rex S , 548, 554 Spiegelberg, H. L., 751 Spleen, response to sound stress, 17 Staphylococcal antibodies in germfree mice, 358 Staphylococcus aureus, intracellular killing of, by human blood leukocytes, 804 Stavitsky, Abram B., 741 Stebbins, M. R., 81 Steffen, Carl, 337 Steigman, Alex J., 512 Stoenner, Herbert G., 770 Stollerman, Gene H., 607 Stone, W. H., 857 Streptococcal and tissue antigens, 595 - - NADase, 793 Streptococci, group A, properties of antigen in certain strains of, 595 Stress and susceptibility to viral infection, 17, 21 Sugahara, Takao, 960 Sulitzeanu, Dov, 424 Suszko, Irena M., 829, 836 Sutherland, G. Bonar, 438, 444 Suzuki, Nachiko, 819 Synthesis, temporal, of chicken antibodies, 399 Talal, N., 246, 257 Tanenbaum, Stuart W., 318 Tannic-acid treated erythrocytes, preparation and use for detection of antigen and antibody, 741 INDEX - - treatment, effect on sensitization by soluble antigen, 663 Terres, Geronimo, 217 Thomas, E. Donnall, 324 Thomas, Lewis, 929 Thorbecke, G. J., 60 Thormar, Halld6r, 185 Thorotrast, intravenous administration of, effects, 54O Thymectomy, effect on precipitin and hemagglutinin production, 878 q -- - survival of skin homografts, 872 Thymus, response to sound stress, 17 Thyroid extract, alterations in thyroiditis induced by, 178 Thyroiditis, allergic, suppression of, 178 Tissue culture assay, competition of soluble antigens by, 685 - - p r e p a r a t i o n s , immunofluorescent studies of, 836 heart, immunologic studies of, 725 Tissues, splenic, factors affecting primary and secondary antibody production by, 672 Tolerance, acquired, and sensitization in mice, 217 --, adoptive, 29 --, immunologic, antigen dosage in, 703 Toxins of Clostridium botutinum, immunity to, 697 Toxoid, botulinum, immunologic response to, 697 Trachoma virus strains, classification, 849 Trams, Eberhard G., 372 Triose phosphate dehydrogenase, ribonueleoprotein-bound antibody to, 734 Trivedi, J. C., 506 TSH, partially purified, 843 Tuberculin purified protein derivative, "cellfixed" antibodies to, 52 Tuberculostatic activity of normal human sera, 711 Tularemia, delayed by hypersensitivity and immunity in, 209 Tumor, mouse ascites, specificity of antisera to, 24 Tureotte, R., 52 Twedt, Robert M., 952 Typhus, opsonizing antibodies in, 127 -- Unresponsiveness, immunologic, to purified proteins in guinea pigs, 368 --, induction in mice with pneumococcal polysacchaxide, 929 - - t o bovine serum albumin, absence of antibody producing cells during, 478 977 Updyke, Elaine L., 358 Urso, Paul, 897 Vaccine, killed virus, enhanced potency of, 429 --, Salk, rooster antigenicity test for, 193 Vaccines, virus, lipid-adsorbed, 1 Vaccinia virus, effect of horse serum on quality of, 647 Vesicular stomatitis virus, sound stress and susceptibility to, 21 Vinograd, Jerome, 619 Viral infection, stress and susceptibility to, 17, 21 Virus, infectious, development in HeLa cells infected with reovirus, 548 --vaccines, lipid-adsorbed, 1 --, vaccinia, effect of horse serum on quality of, 647 --, visna, neutralization of, 185 Viruses, animal, neutralization, 140, 151 --, influenza, antigenic analysis of, 172 Visna virus, neutralization by sheep antisera, 185 Walker, Harold G., 925 Walter, Paul C., 448 Wang, San-pin, 849 Wannamaker, Lewis W., 793 Wardlaw, Alastair C., 925 Watson, Dennis W., 782 Watson, R. Glenn, 238 Webster, R. G., 140,151 Weigle, William O., 935 Weiner, Lawrence M., 788 Weyand, James G. M., Jr., 741 Wilhelm, D. L., 43 Wisseman, Charles L., Jr., 127 Witebsky, Ernest, 908 Wolfe, Harold R., 872, 878 Wood, Jane G., 127 Wood, W. Barry, Jr., 914 Wust, Carl J., 734 X-irradiation and allergic encephalomyelitis, 532 -----, total body, effects, 540 Yagi, Yasuo, 424, 760 Yokoyama, Mitsuo, 372 Youngner, J. S., 1 Zeldow, Bernard J., 12
