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Chapter 16 – The Respiratory System - Pulmonary ventilation – movement of air between the external environment and the air sac w/in lungs - External respiration – exchange of gases between the lungs and bloodstream - Internal respiration – movement of oxygen and carbon dioxide between the bloodstream and body cells - Respiration – entire process of gas exchange between external environment and body cells Organs of the Respiratory System - Upper respiratory system – head and neck -organs: nose, pharynx, larynx -Lower respiratory system -organs: trachea, bronchi, bronchioles, alveoli, lungs (bronchi, bronchioles, alveoli, and supporting tissues) -Conduction zone – organs that conduct air between the external atmosphere and air sacs in lungs; -warm and humidify air as it passes through -includes nose, pharynx, trachea, bronchi, and bronchioles -Respiratory Zone – organs involved in actual gas exchange -includes alveoli and associated structures Nose -provides and internal chamber for inhaled air; formed by 2 nasal bones and numerous cartilages -external nares (nostrils) – openings at base of nose separated by a partition at the midline called the nasal septum – divides nasal cavity in half, opens into vestibule -vestibule – chamber that contains hairs that help filter particles from inhaled air; opens into larger space (nasal cavity) -nasal conchae – bony projections that separate the nasal cavity into narrow passageways called meati -nasal cavity is lined w/ mucous membranes w/ abundant blood vessels which warm and moisten air -external layer of mucous membranes is lined w/ cilia which beat together to create a flow of mucous that moves toward pharynx; traps particles that are swallowed -paranasal sinuses – connected to nasal cavity by small ducts; lined w/ mucous membranes -sinusitis – tubes become swollen/plugged up, causing infection Pharynx -Throat – chamber that extends from the back of the nasal cavity to larynx; skeletal muscle walls lined w/ mucous membranes; receives air from nasal cavity through 2 small openings called internal nares -divided into 3 segments 1) nasopharynx – superior section, receives internal nares and auditory tubes (connect to ear) 2) oropharynx – visible 3) laryngopharynx – below tongue level, unites w/ larynx in neck -oropharynx and laryngopharynx – common passageway for air and food Larynx - voicebox – connects pharynx w/ trachea -prevents solid material from entering trachea -houses vocal cords which produce sound -cartilage walls (9 pieces in a box shape) lined w/ mucous membranes -thyroid cartilage – front piece (enlarged in males = Adam’s apple) -epiglottis – suspended by muscles and ligaments over the glottis opening of larynx -upright position to allow air to pass through, except during swallowing epiglottis moves downward to seal off glottis -false vocal cords – move larynx up during swallowing, do not function in sound production -true vocal cords – vibrate back and forth in response to air, produce sound, mucous sometimes accumulates b/c there is no cilia present to move it must clear throat Trachea -windpipe – tubular passageway in front of esophagus (food tube) -12cm long + 2.5cm wide -extends from larynx to thoracic cavity where it divides into left and right bronchi -walls are supported by cartilage rings (C’s open in back), smooth muscle, and elastic fibers -rigid – prevents collapse and closing off air passage -C’s allow esophagus to expand as food moves through -internally lined w/ ciliate mucous membranes – contain large #’s of mucous-secreting cells -mucociliary transport system – mucous covered cilia move trapped particles upward toward pharynx where they are swallowed Bronchial Tree -trachea splits into a left and right primary bronchus, which lead into each lung -left bronchus branches off at a sharper angle, so accidentally inhaled substances usually go into right lung -each bronchus branches extensively into smaller and smaller tubes resembling a tree -bronchi are similar to trachea – C cartilage rings, smooth muscle, ciliated mucous membrane -as tubes branch and get smaller, cartilage rings gradually disappear, mucous membranes get thinner, resulting in bronchioles small tubes supported only by a band of smooth muscle and elastic fibers lined w/ a thin mucous membrane layer; very numerous in each lung -bronchioles divide to form smaller tubes called alveolar ducts; which terminate as round, microscopic pouches called alveoli Alveoli and Respiratory Membranes -300 to 500 million alveoli in lungs of average adult -provides only site of gas exchange between external environment and bloodstream -surface area of lung is size of tennis court: necessary to meet metabolic needs of body -each alveolus consists of a microscopic air space surrounded by a thin wall, which separates one alveolus from another and from capillaries -wall is made of a single layer of squamous epithelium w/ cells that secrete surfactant (layer of lipid molecules) -surfactant lines inner surface of alveolar wall along w/ thin watery fluid layer -necessary for surface to be moist for diffusion of gases to occur -water in fluid has surface tension strong, attractive force that causes alveolar walls to collapse when air is exhaled -surfactant counters this force; reinflating alveoli -wall of each alveolus is very close to a capillary wall to promote rapid diffusion of gases -respiratory membrane – close arrangement of epithelial wall of alveolus and capillary wall, basement membrane of connective tissue Lungs - consist of bronchial tree, alveoli, capillaries, and supporting tissues General Characteristics - soft, spongy, cone-shaped -extend from diaphragm to just below clavicles, bordered by ribs -right lung is thicker and broader b/c of liver -apex – narrow, superior region -base – broad, inferior region -costal surface – lies against ribs in front and back -medial surface – faces the midline toward the heart -each lung attaches to the trachea and heart only on medial surface -root – collection of attachments including primary bronchus, large blood vessels, and nerves Serous Membranes -pleurae – 2 layers of serous membranes surrounding each lung -parietal pleura – outer layer, lines thoracic wall and mediastinum, continues around heart and between lungs where it combines w/ parietal pleura of other lung and forms a ligament supporting both lungs -visceral pleura – inner layer, surrounds each lung, firmly attached to outer surface -pleural cavity – space between 2 pleural layers containing fluid secreted by serous cells in pleurae -reduces friction between membranes as lungs expand or contract -pleurisy – inflammation of membrane or reduction in fluid causing membranes to scrape against one another Divisions -right lung has 3 compartments or lobes and is larger than left lung – only 2 lobes -fissures – lines of division between lobes -each lobe is supplied by a major branch of bronchial tree and enclosed by connective tissue -lobes are divided into segments -each segment contains many lobules