Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Warm-Up (12/02) On the piece of white paper from the back, answer the following question. Explain the difference between the lytic cycle and the lysogenic cycle. What do they both have in common? Name Date Period Retroviruses • Normal viruses contain DNA and inject that DNA into a host cell. • Retroviruses contain RNA. RNA injected RNA DNA reverse transcriptase RNA (gene expression) Retroviruses • Normal viruses contain DNA and inject that DNA into a host cell. • Retroviruses contain RNA. RNA injected RNA DNA reverse transcriptase RNA (gene expression) If I wanted to target HIV fight it without hurting human enzymes, which enzyme should I target? HIV HIV goes through the lytic cycle and acquires mutations very rapidly. ∴, it evolves very rapidly. “retroviral” drugs HIV HIV goes through the lytic cycle and acquires mutations very rapidly. ∴, it evolves very rapidly. “retroviral” drugs HIV HIV goes through the lytic cycle and acquires mutations very rapidly. ∴, drug resistance can happen easily. “retroviral” drugs Critical Thinking Question #1 Discuss this question with your partner and write or represent it. I will call on three people to share their partners’ answers. Explain how HIV strains can become resistant to anti-retroviral drugs. What makes HIV so bad? DNA RNA injected DNA injected RNA Host cell machinery, including errorchecking enzymes RNA (gene expression) Host cell machinery, including errorchecking enzymes DNA RNA (gene expression) What makes HIV so bad? RNA DNA Mutations! Mutations! injected DNA injected RNA No error checking! Host cell machinery, including errorchecking enzymes RNA (gene expression) Host cell machinery, including errorchecking enzymes DNA RNA (gene expression) Critical Thinking Question #2 Discuss this question with your partner and write or represent it. I will call on three people to share their partners’ answers. Draw the lytic cycle of the HIV virus (as you did yesterday), showing reverse transcriptase. Also indicate the point at which the genetic material can acquire mutations much more rapidly than DNA-based viruses. Closure On the piece of white paper from the back, answer the following question: Why do retroviruses evolve more rapidly than DNA-based viruses? Name Date Period Scale 1 – 10