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Congenital Heart Disease 6/2/11 FANZCA Part II Notes Burns, J et al (2002) “Anaesthesia for non-cardiac surgery in patients with congenital heart disease” BJA CEPD Reviews, Vol 2, Number 6, pages 165-169 AHA/ACC Guidelines: Prevention of Infective Endocarditis (2007) – Summary Statements Lovell, A.T. (2004) “Anaesthetic implications of grown-up congenital heart disease” BJA 93 (1) pages 129-139 Talley and O’Connor CLASSIFICATION Acyanotic Left -> right shunt - VSD ASD atrioventricular septal defect PDA No shunt - bicuspid aortic valve, aortic stenosis pulmonary stenosis tricuspid stenosis coarctation dextrocardia Ebstein anomaly (inferior displacement of tricuspid valve into RV) Cyanotic - TOF transposition of great vessels hypoplastic left heart pulmonary atresia Eisenmengers syndrome (later in life -> PHT with right -> left shunt) trunkus arteriosus tricuspid atresia total anomalous pulmonary venous drainage OPERATIONS Blalock-Tausig shunt placement – palliative care procedure where subclavian artery connected to the pulmonary artery Jeremy Fernando (2011) Fontan circulation: 1. 2. 3. 4. SVC anastamosed to the right pulmonary artery, homograft valve insertion in the IVC, closure of ASD, connection of RA and PA by a valved homograft conduit. Bidirectional Glenn Shunt – for hypoplastic left heart syndrome where SVC is anastamosed to the PA (usually used as a staging procedure to a Fontans circulation) Tetralogy of Fallot Repair: 1. large VSD, 2. RV outflow tract obstruction, 3. RV hypertrophy, 4. Overriding aorta. -> complete correction undertaking during infancy VSD repair – surgical closure and percutaneous closure options (both are associated with problems with ventricular arrhythmias post op) ASD repair – percutaneously closed HISTORY - diagnosis (when, how, age) treatment (corrective, palliative or untreated) symptoms (cyanosis, heart failure symptoms, pulmonary hypertension symptoms, functional capacity history of stroke or thrombosis (hyperviscosity) EXAMINATION - SpO2 - CHF signs INVESTIGATIONS - FBC: HCT (high), platelets (low) - U+E: renal dysfunction from chronic hypoxia - Coags: coagulation factor deficiencies common in cyanotic heart disease - ECHO: diastolic dysfunction, decreased ejection fraction, nature and size of lesion, flow reversal, MANAGEMENT Preoperative - identification of seriously effected patients with transfer to regional unit - premedication (decrease O2 consumption and sympathetic tone) Jeremy Fernando (2011) Intraoperative - all IV induction agent safe (rate of delivery and dose important not actual drug) - good analgesia (decrease sympathetic activation) - 100% FiO2 can be used in simple cardiac anomalies with left to right shunt (but caution with complex lesions with right to left shunt) - controlled ventilation - invasive monitoring - TOE helpful (PAC not so much) - capnography underestimates in patient with right to left shunt - pulmonary hypertension management (to decrease PVR; increase FiO2, hypocarbia, akalaemia, SV, normal lung volumes, avoid sympathetic stimulation, isoprenaline, milrinone, prostaglandins, NO, sudenafil) - endocarditis; see guidelines below Postoperative - HDU/ICU - management of pulmonary hypertension and systemic haemodynamics - hypoxaemia; from either inadequate pulmonary blood flow (avoid dehydration, maintain SVR, control PVR, minimise oxygen consumption) OR pulmonary hyperperfusion (minimise cardiac work) Esienmenger Syndrome = high pulmonary vascular resistance with reversed or bidirectional shunt flow - can be caused by a number of defects - definitive treatment = to close defect - goal when managing is not to decrease SVR and cause -> increase in right to left shunt, worsening cyanosis and death - arrhythmias, hypovolaemia and large fluid shifts not tolerated well - no air bubbles - invasive monitoring with anticipation and treatment of haemodynamic changes Infective Endocarditis Prophylaxis - more conservative approach as risks of adverse effects from antibiotics higher than risks of developing IE from dental, GI or GU tract procedure - high risk patients or procedures that require antibiotics; 1. 2. 3. 4. 5. any prosthetic material in heart previous IE unrepaired congenital cyanotic heart disease cardiac transplant patients with valvulopathy all dental procedures that involve manipulation of gingival tissue or periapical region of teeth or perforation of oral mucosa (thus only check ups and simple fillings that don’t involve gingiva don’t need antibiotic prophylaxis) Jeremy Fernando (2011)