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Dr S Programme Physiology MCQ [File MCQPHYS3] Respiration/alimentary tract/kidney Type A 1. rest: a) b) c) d) e) Select which of the following would NOT be expected in a 70 kg male at 2. a) b) c) d) e) At 37 degrees under which conditions of pH of the blood is constant: HCO3 to H2CO3 ratio remains constant the bicarbonate concentration always falls when CO2 is added as oxygen is given up an equal quantity of carbon dioxide must be taken up the carbonic acid concentration must be constant the carbon dioxide content cannot be reduced without producing hypoxia inspiratory reserve volume of 3500 ml expiratory reserve volume of 1000 ml tidal volume of 500 ml residual volume of 2500 ml physiological dead space of 150 ml 3. When the CO2 diffuses into the blood across the systemic capillaries the size of the erythrocytes is: a) increased because of the increased intracellular osmoles b) increased because of the increased intracellular osmotic pressure c) unchanged because of the Donnan equilibrium d) decreased because chloride ions diffuse out of erythrocytes e) increased because bicarbonate ions are formed within the erythrocytes 4. Identify the inconsistent value a) total arterial blood gas pressure = 755mmHg b) total alveolar gas pressure during quiet expiration at sea level +763 mmHg c) total alveolar gas pressure at the end of inspiration at all altitudes is given by (total pressure of gases-water vapour) +47 mmHg d) total venous blood gas pressure at sea level is 755mmHg e) total alveolar gas pressure during a deep inspiration at sea level =755mmHg 5. A normal healthy man undergoes a journey of 30 minutes duration in an unpressurised cabin of an aircraft at 20,000 feet. Atmospheric pressure falls by approximately 100mmHg for each 5000 feet ascent from sea level: a) cyanosis could present because the alveolar PO2 is decreased b) ventilation is increased because the PCO2 is decreased c) his oxygen utilisation coefficient will fall due to reduced atmospheric PO2 d) expiratory reserve volume is increased because of the lowered atmospheric pressure e) haemoglobin concentration in the blood rises because of the tissue hypoxia 6. A man with a respiratory dead space of 1250 ml inspires 18 litres of air per minute at a rate of 20 breaths per minute and has an oxygen consumption of 300L/min. Which of the following statements is correct? a) he has a vital capacity of 4 litres b) c) d) e) he has an alveolar ventilation of 15L/minute he is hypoventilating he has a tidal volume of 1050 ml he has a minute volume of 24 litres 7. In the respiratory tract: a) the major resistance to airflow is provided by the bronchi b) bronchial resistance is increased by an increased alveolar PCO2 c) bronchial resistance is decreased by beta blockers d) the major resistance to airflow is provided by the upper respiratory passages(above the trachea) e) bulk flow of air from the terminal bronchioles to alveoli is increased by adrenaline 8. a) b) c) d) e) Identify the inconsistent value at sea level alveolar PCO2 =40mmHg alveolar PO2 = 100mmHg alveolar PH2O = 47 mmHg alveolar PN2 = 573 mmHg PO2 of inspired air =130 mmHg 9. a) b) c) d) e) Identify the inconsistent value on average arterial P02 = 95 mmHg arterial blood oxygen content is 210 ml/L PO2 of mixed venous blood is 40 mmHg oxygen content of mixed venous blood is 140 ml/L at a PO2 of 70 mmHg, blood oxygen content is 170ml/L 10 Identify the inconsistent value in these measurements on a mixed venous blood sample obtained in a healthy person from the inferior vena cava at sea level: a) PO2 = 40 mmHg b) PCO2 = 48 mmHg c) PN2 = 620 mmHg e) oxygen content = 156 ml/L blood e) CO2 content = =540 ml / l blood 11. After inspiration commences, the: a) intrapleural pressure and the intrapulmonary pressure both fall b) intrapleural pressure falls and the intrapulmonary pressure rises c) intrapleural pressure falls and the venous return to the heart decreases d) intrapulmonary pressure falls and the volume of the alveoli is momentarily unchanged e) intrapleural pressure rises and the venous return to the heart decreases 12. a) b) c) d) e) Which of the following results in an increase of pH of the duodenal contents? gastrin secretin bombesin intrinsic factor motilin 13 a) b) c) d) e) A 24 hour urinary ammonia excretion of 75 mmol: could be associated with chronic diarrhoea would be favoured in potassium overload is within the normal range could be associated with prolonged vomiting would require a urinary volume in excess of 2 litres 14. In comparison with the concentration in arterial plasma, which one of the following is INCORRECT? a) by the end of the proximal tubule the sodium concentration is the same b) by the end of the descending limb of the loop of Henle, chloride concentration has increased markedly c) by the end of the proximal 16. a) b) c) d) e) A shift of the oxygen dissociation curve fior blood to the LEFT is favoured by a rise in temperature favours the passage of oxygen from blood to the tissues occurs when fetal blood is replaced by adult blood occurs in the pulmonary arteries occurs with a fall in pH 17. a) b) c) d) e) Which of the following is true compliance is directly proportional to the change in pressure compliance is directly proportional th the work of breathing complaince is directly proportional to the change in volume complinace decrease with lung oedema compliance increases with lung oedema 18. a) b) c) d) e) in the large intestine the major proportion of intestinal water is absorbed a substantial proportion of the daily requirement of vitamin A is synthesized by bacteria aldosterone stimulates potasssium absorption segmentation is a common pattern of motility aldosterone influences bowel motility 19. a) b) c) d) e) The cells of the liver can: convert all amino acids into glucose convert acetyl Co-A into pyruvic acid store vitamin C unable to store glycogen store folic acid 20. An alkaline urine a) occurs in respiratory alkalosis b) cannot have a pH greater than the pH of the plasma from which the urine is formed c) d) e) occurs in uncomplicated metabolic acidosis does not contain ammonia does not increase the urinary excretion of salicylate Answers 1D 2A 3A 4D 5A 6B 7D 8E 9E 12B 13A 14E 15D 16D 17D 18D 19E 20A 10C 11A