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Circulatory System Chapter 4 4-1 The Body’s Transportation System • Main job of circulatory system – Delivers food & Oxygen to cells – Carries Carbon Dioxide & other waste products away from cells • Powered by Heart • Blood vessels are main passage – Extremely extensive (large, complex) • Oxygen & food = Energy – Energy needed for cell life – 1st to die w/o Oxygen – Brain Cells • Important tasks of Circulatory System – Delivery of Oxygen to body cells – Removal of Carbon Dioxide – Supplies body with defenses (chemicals) against Bacteria/Viruses – Carries chemical messengers for communication 4-2 Circulation in the Body • • • • Heart → Lungs → Heart Blood→ Body Cells→ Heart Heart = muscle (only rest btwn beats) Anatomy of Heart – Left chest – Fist or grapefruit – Heartbeat = rhythm – Pacemaker – area of nerve tissues that regulate the heart’s pace (upper right side of heart) • Regulates muscle contractions of heart Right Side • 2 pumps in Heart – right & left sides – Septum (thick tissue wall) separates the 2 sides of heart – 2 chambers on each side • Right Atrium – Collecting chamber – Dark red, Oxygen-poor blood – Receiving blood from body carrying waste Carbon Dioxide • Right Ventricle – Valve divides the 2 chambers – Pumping chambers – Leaves heart through large vessel – Pumps blood to Lungs To the Lungs and Back • Right ventricle pumps blood to lungs – RBC drop off carbon dioxide (exhaled) – RBC pick up oxygen (inhaled) – RBC carry oxygen to body cells – Hemoglobin + Oxygen = Oxygen-rich blood (bright red) – Oxygen-rich blood enters back into heart • Left Atrium Left Side • Left Atrium – collecting chamber – Oxygen-rich blood flows through valve – Enters left ventricle • Pumps blood throughout body • Left side works abt 6x harder than right side Arteries: Pipeline from the Heart • Carry blood away from the heat • Aorta – largest blood vessel in the body – Arteries branch out sending oxygen-rich blood throughout the body and some back to the heart – 3 layers • Smooth inner layer (easy flow) • Elastic middle layer (smooth muscle tissue) contract/relax to move blood • Outer layer (flexible connective tissue) stretch and return to normal size with heartbeat • Blood is sent to body location according to priority – Eating, exercising, waste removal, repair • Blood always goes to the brain Capillaries: The Unseen Pipelines • Thin walled vessels (RBC in single file) • Blood’s work occurs here – Remove oxygen and pick up waste – Pass in and out of capillaries thin walls – Blood becomes dark red (no oxygen) Veins: Pipelines to the Heart • Blood trickles capillaries →veins → heart • Veins thicker that capillaries but thinner that arteries – One-way valves to prevent blood from back-flowing Blood – The River of Life • • • • Blood – tiny particles floating in a fluid Fluid tissue (1 of 2 in body: Lymph) 4 Components of Blood: Floating particles: – Red blood cells – White blood cells – Platelets • Fluid portion: – Plasma Plasma • 90% water • 10% - sugars, fats, salts, gases, plasma proteins – 3 Groups of Plasma Proteins • Regulate amt of water entering & leaving blood • Antibodies – special proteins to help fight of diseases • Blood clotting • Plasma carries digested food, hormones and waste products Red Blood Cells • Most numerous in body – Look like tine berets – Centers very thin, enabling them to bend in order to move through capillaries • Produced in bone marrow • Contains a nucleus in early stages but then shrinks as cell ages – Very delicate & only live for abt 120 days – Die at a rate of 2million/sec – New rbc form at abt the same rate – Old/dying rbc broken down in liver & spleen • Spleen: aka “cemetery” of rbc • Hemoglobin – iron-containing protein found in rbc – Build-up of hemoglobin forces out nucleus – Oxygen binds with hemoglobin to be carried throughout body – Binds with carbon dioxide also White Blood Cells • • • • Larger than rbc and live longer (mths or yrs) Developed in bone marrow Keep nucleus Main function to protect body from disease, bacteria, viruses, etc – Surround and digest invaders – Make antibodies – Produce special chemicals to fight diseases Platelets • Aid in the clotting of blood • Platelets burst open when a cut occurs producing the chemical Fibrin – Act as a net, weaving a fiber across a cut trapping plasma and cells – Hardens and then clots (scab) • Fragments of cells – No nucleus, no color – Break off from larger cells produced in bone marrow Blood Groups • Transfusion – transferring of blood from 1 person to another • Clumping chemicals – proteins on the outer coats of rbc that react with different proteins • A and B: proteins in red blood cells • anti A and anti B: proteins in the plasma – Named for their reaction to A & B • 4 Basic Blood Groups –A –B – AB –O • • • • • A people contain A protein B people contain B protein AB people contain A & B proteins O people contain neither A or B proteins Transfusions must be compatible – Donor – person giving blood – Recipient – person receiving blood – Both tested to find out blood type • anti A & anti B chemicals needed when wrong blood type is not used or available in a transfusion • O blood type contains A& B anti chemicals – anti A causes rbc containing protein A to clump together – anti B causes rbc containing protein B to clump together • A blood receive A or O • B blood receive B or O • O blood only receive O • AB blood receive A, B, AB & O • Rh Blood Group – 18 other proteins found on the surface of rbc – Found on rhesus monkeys – Rh+: contain any 1 of the 18 proteins – Rh-: do not contain any of the 18 proteins