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Biol 212 Worksheet: Energetics Supplemental Instruction Iowa State University Leader: Course: Instructor: Date: Greg Biology 212 (2) Kukday 9/17/15 1. REVIEW: What are the two laws regarding energy? Why are they important? 1st – Energy isn’t created or destroyed, just transferred. Means we need to get energy from a source (ie. Plants get energy from the sun, us from food) 2nd -- Transfer of energy increases entropy; ie energy becomes more disordered 2. REVIEW: Briefly describe how ATP hydrolysis releases energy. Bond breaking of the phosphate group requires energy, but the forming of the new Hydrogen bonds releases much more energy 3. REVIEW: What are enzymes? How are they regulated? Enzymes are natural catalysts, normally proteins. Regulated by both inhibitors and activators. Feedback inhibition is important as the products regulate a sequence of reactions. 4. Process Location Starting Materials Final Materials Anaerobic or Aerobic? Glycolysis Cytoplasm Glucose 2 ATP Oxygen 2 Pyruvate Independent 2 NADH+ H+ Alcoholic Yeast Pyruvate Alcohol and CO2 Anaerobic Fermentation 2 ATP Lactate Eukaryotes Pyruvate Lactic Acid Anaerobic Fermentation 2 ATP Pyruvate Matrix of the Pyruvate Acetyl CoA Aerobic Processing Mitochondria 2 ATP Citric Acid Matrix of the Acetyl CoA 6 NADH+ Aerobic Cycle Mitochondria 2 FADH2 2 ATP 6 CO2, Electron Inner Oxygen 28 ATP Aerobic Transport Chain Membrane of NADH H2O the FADH2 Mitochondria 5. What does pyruvate dehydrogenase do? What is a treatment for PDH deficiency? PDH converts Pyruvate to Acetyl CoA. A treatment is a high fatty diet. 6. Briefly describe Patrick’s case study. What was wrong with Patrick? Patrick had a genetic condition such that he had a deficiency of PDH. 7. TEST QUESTION: Which of the following is not true regarding energy? a. Potential energy represents stored energy; eg. energy in chemical bonds. b. Kinetic energy represents the energy of motion; eg. heat energy. c. The first law of energy states that energy cannot be created or destroyed. d. The second law of energy states that transfer of energy decreases entropy. 8. TEST QUESTION: In humans, when oxygen is not present, what is the next step in the metabolic pathway after glycolysis? a. Lactate Fermentation c. Alcoholic Fermentation b. Citric Acid Cycle d. Electron Transport Chain 1060 Hixson-Lied Student Success Center 515-294-6624 [email protected] http://www.si.iastate.edu