Download Introduction: Hemoglobin is an essential protein necessary for the

Introduction:
Hemoglobin is an essential protein necessary for the transport of oxygen and carbon dioxide in the body.
Biochemists study the molecular activities necessary for the exchange and transport of oxygen and carbon dioxide
between the body cells and lungs.
As a biochemist you have been asked to design a presentation for students studying to be laboratory technologists on
hemoglobin.
Task:
Design a multimedia presentation (e.g., PowerPoint, Prezi)to teach laboratory technology students about hemoglobin
and genetically transmitted molecular disease. Your presentation will be composed of two parts:
A. Hemoglobin
1. Provide a model of hemoglobin that shows how oxygen is carried by the molecule.
2. Explain the major differences between the oxygenated and deoxygenated states of hemoglobin.
3. Create original diagrams that compare the biochemical structure of hemoglobin to myoglobin.
a. Clearly label diagrams to show the comparison.
B. Sickle cell anemia
1. Provide two diagrams that meet the following requirements:
• A diagram that demonstrates the molecular difference between normal and sickle forms of
hemoglobin.
• A diagram that demonstrates the difference between normal and sickle red blood cells at the cellular
level.
2. Describe how the diseased cells are different from normal red blood cells in the context of their capacity to
carry oxygen.
3. Explain the molecular inheritance of sickle cell anemia.
a. Use diagrams to demonstrate your explanation.
Rubric:
This assignment is worth 600 pts.
_____PowerPoint = 50 pts.
_____Colorful / includes 10 pictures = 50 pts
_____ Create All Models and Diagrams outlined above = 200 pts
_____ Explain the major differences between the oxygenated and deoxygenated states of hemoglobin = 100 pts
_____ Describe how the diseased cells are different from normal red blood cells in the context of their capacity to
carry oxygen = 100 pts
_____ Explain the molecular inheritance of sickle cell anemia = 100 pts