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All living things… Are composed of _______________ ▪ These are the basic units of structure and function. Maintain balance within themselves, known as _________________ ▪ Internally an organism stays the same even when the outside atmosphere changes. Undergo chemical reactions that power an organism called _____________________ ▪ Living things use energy to grow and develop by the use of chemical reactions. Pass on hereditary information to new organisms through ________________. Only living things will perform or have these four characteristics. Nonliving things have no functioning cells, have no metabolic activity, do not maintain homeostasis and do not reproduce in any way. Even though all living things have ___________, undergo _______________, maintain____________, and _____________, there are still many differences between living things. We can __________ or group organisms together based on similarities between these organisms. We group organisms into ______________ All living things can also carry out life processes They may be carried out in different ways ▪ Getting _______ from the environment and breaking them down for transport ▪ Ingestion, digestion, egestion ▪ Transporting materials throughout organism ▪ Breaking nutrients down to release energy, ______________________________ ▪ Combine simple substances to make complex ones, ____________________ ▪ Increasing the size or number of cells through _______________ ▪ Removing waste through excretion ▪ Sweating, urination, diffusion, breathing ▪ Responding to internal and external stimuli ▪ Reproducing more of their own species ▪ Asexual reproduction, sexual reproduction All things (living or nonliving) are made of atoms Atoms are made of 3 subatomic particles Nucleus of an atom contains Protons: Neutrons: Orbiting around the nucleus of atoms are ______________: Atoms are the smallest particle that retains its individual chemical properties Density: Reactivity: Conductivity: Atoms create elements Periodic table Atoms “want” full outer orbital Ion is an atom with a charge Atomic number is equal to the number of protons Atomic mass is equal to the number of protons plus the number of neutrons An isotope is when an atom has a difference number of neutrons within the nucleus A radioisotope is the number of neutrons or protons vary and emit particles Radiation Can be used for energy or medical uses https://www.youtube.com/watch?v=aNK1mQfNeik All living things are made of mostly 4 main elements Carbon, ______________, Oxygen and Nitrogen Elements come together through bonds form molecules Types of bonds: Ionic, Covalent, and Metallic bonds Two types of molecules: Organic and Inorganic molecules Ionic Bonds: An electron is lost or gained (transfer) Creates a charge: Protons vs. Electrons Covalent bonds: 2 or more atoms share electrons 2 Hydrogen and Oxygen = water Metallic bonds: ability of electrons to move freely between atoms of the same metal This allows for electrical conductivity DO not have BOTH __________ and hydrogen Can have any combination of elements (except both C and H) Salts and minerals Acids and bases Oxygen ( ) Carbon Dioxide ( Water ( ) ) ▪ The most abundant substance in any organism Contain both ___________and ____________ These are the major types of molecules of life. Structural molecules (Make up cell membranes) Active molecules (enzymes that carry out chemical reactions) Nucleic Acids, Protein, Lipids, and Carbohydrates (like glucose, C6H12O6) Store energy and provide structure in plants Starch compound made of glucose molecules. Glucose simple molecule that provides energy Lipids are compounds that store energy and can act as barriers in membranes Oils are lipids that are liquid at room temperature Fats are lipids that are solid at room temperature Proteins are organic compounds that provide structure in non-plant species can be markers or receptor molecules carrier molecules in membranes serve as enzymes Amino acids are the building blocks of proteins Enzymes are proteins that act as catalysts Enzymes can speed up chemical reactions by lowering the activation energy Enzymes act on substrates The enzyme acts on the substrate at the “active site” Shape specific (puzzle pieces) They them combine together to form the enzyme- substrate complex High temperatures, pH changes, heavy metals, and viruses can cause enzymes to change their shape making them less or ineffective this is called denaturing Denaturing enzymes is consequential because once an enzymes shape is changed it will no longer function as well or in some cases at all. Even if the conditions return to normal the enzymes cannot change its shape back to what it was. It is a permanent change Eg: High fevers or body temperatures If temperatures are decreased the enzyme activity would slow down If temperature is returned to normal so does enzyme activity Are organic compounds that contain the genetic code for an organism Building blocks = nucleotides DNA = deoxyribose nucleic acid RNA = ribose nucleic acid Molecules are constructed by removing a water molecule Splitting of a molecule by adding water The inverse of dehydration synthesis A scale that tells you how acidic or basic a solution is Based on hydrogen concentration ( )in relation to the hydroxide concentration ( ) Move H+ ions at low pH, more OH– at high pH ▪ Human body pH ~7.4; if altered more than .1 could be deadly Chemical formula is ______________ Structure: Polar molecule There is a charge on either side Properties: Polarity make sit a good solvent (dissolve stuff) Adhesion: water ability to chemical :stick” to other molecules ▪ Capillarity – ability to move upward, against gravity Cohesion: water is able to “stick” to itself ▪ Rain drops Potential energy is stored energy Kinetic energy is energy in motion Chemical Change (Reaction) - change the chemical formulas and the properties have changed Burning wood Physical Change (Phase change) – the chemical formula and properties are still the same, but the phase of the material has be changed Freezing/melting water Phases of matter: Types of chemical reactions: Endothermic – heat is absorbed – feels cool ▪ cold pack Exothermic – heat is released – feels warm ▪ Hot packs for hands Decomposition – large molecules are broken down into smaller molecules ▪ Hydrogen peroxide on a cut Synthesis – smaller molecules are combined to build larger ones ▪ Making water Replacement reactions – molecules are switched ▪ Changing partners Dissolving things Solute: substance that gets dissolved Solvent: substance that does the dissolving Solution: solute and Solvent No chemical reaction Suspension: particles are held up but will settle out Colloid: suspension when particles do not settle out gelatin Monomer: Simple molecule Sugar Polymer: more than one monomer Starch Macromolecule: a very large molecule Starch Monomers link together and build up through dehydration synthesis Polymers are broken apart by hydrolysis Monosaccharides: simple sugar Glucose, fructose, galactose: -ose Disaccharide: 2 sugars Polysaccharide: many sugars We can link organisms that share a similar “building plan” The basic structures and functions in living things Simple organisms are just one cell, _______________________________ Complex organisms consist of billions of cells Organisms of more than one cell are known as _______________________ organisms What led to the discovery of the cell? Lens Light Microscope SEM – Scanning electron microscope TEM – transmission electron microscope 13th century – Salvino D’Armate – Italy First eye glass – magnification for one eye 1590’s – Zacharias Jansen and his father Hans Dutch spectacle makers They put several lens in a tube and saw that what was near the end of the tube was magnified. 1665 – Robert Hooke Study cork through his microscope Names the cell after its cubical appearance 1675 – Anton van Leauwenhoek – Dutch First man to make and use a more modern microscope First to view living cells 1838 - Matthias Schleiden – German Botanist – concluded that all plants were made of cells 1839 - Theodor Schwann – German Best known for cell theory Discovered the Schwann cells in the peripheral nervous system Concluded that all animals are made out of cells 1855 – Rudolf Virchow – German Doctor – determined that all cells come from other cells while he was studying diseases Cell Theory was created from the discoveries of these individuals Cell theory states that: All living things are made of one or more cells Cells are the basic unit of structure and function in organisms Cells come from existing cells Cells can vary in size from 2 meters to 0.2 micrometers Most plant cells are 10 – 50 micrometers What cell is 2 meters long? http://www.bozemanscience.com/why-are-cells-small Cells can’t be that large Surface Area: Volume ratio!!! ▪ 1 cm x 1 cm x 1 cm = 1 cm3 ▪ Volume with 6 cm2 ▪ surface area = a 6:1 ratio ▪ 3 cm x 3 cm x 3 cm = 9 cm3 ▪ Volume with 27 cm2 ▪ surface area = a 3:1 ratio Food, waste, oxygen, must diffuse throughout a cell http://www.bozemanscience.com/whyare-cells-small Shape is an advantage for cells As a cell it is great to be out of shape ▪ Adds surface area Shape = function White blood cells are the real shape shifters of the body ▪ they can destroy pathogens or get rid of foreign materials Eukaryotes have membrane bound organelles and a nucleus Plants, animals, fungi, protists are eukaryotes Prokaryotes do not have either Bacteria are prokaryotes Six kingdoms Bacteria= bacteria, fungi = mushrooms, animalia = animals, plantae = plants, protista = single celled organisms, archaea = extremophiles Many organisms are made of only one cell but everything that is living has to have at least 1. Cells are made of a jelly like inside surrounded by a thin _______________. Most cells have ______________that perform specific tasks for the cell, like organs in a body The jelly like substances inside the cell is known as the _____________ It has specialized structures and transports materials throughout the cell. Reactions happen there Reactions are part of which of the 4 major characteristics of life? Made of different molecules, are all different sizes, shapes, and have different functions. They interact to transport materials, form energy from nutrients, build proteins, dispose of waste and store information http://www.discovery.com/tv-shows/othershows/videos/assignment-discovery-shortseukaryote-prokaryotes.htm Large organelle that controls the cells metabolism and _______________________ _______________ DNA in chromosomes The nucleus is like the cell’s “Control Center” because it directs the cell’s activities The storage sacs in the cytoplasm are vacuoles. Can have either useful materials (like food or water) or ______________ in them. Some are specialized to digest food Some are specialized to get waste out of the cell In plants, vacuoles hold lots and lots of water and are much bigger than in animal cells. The cell contains lots of tiny structures that are important for making _______________ Some ribosomes are attached to membranes in the cell Nuclear membrane, rough endoplasmic reticulum Others float around in the ________________ Mitochondria are podshaped structures that contain special proteins, known as _____________ used to extract energy from nutrients Mitochondria are known as the _____________________ of the cell because they release most of the cell’s energy through the life process:_______________ Green structures found in plants and some one-celled organisms are known as chloroplasts. They contain green pigment ______________ and capture light energy, which is then used to produce food for the plant Animal cells do not contain chloroplasts. Endoplasmic Reticulum Continuation of the nuclear membrane that is used to make lipids and proteins. May have ribosomes attached Golgi Apparatus Involved in secretion and intracellular transport The cell membrane is a thin outer lining of a cell. It is made of mainly fats (lipids), with some proteins scattered throughout. Function of the membrane: Separate the inside of the cell from the outside Controlling the transport of materials (like waste) into and out of the cell Recognizing and responding to chemical signals Has 4 layers Hydrophobic Hydrophilic Hydrophilic Hydrophobic Carboxyl Glycerol Glycerol Carboxyl http://www.bozemanscience.com/015-cellmembrane Lipids = fats Oil and water? Protective barrier Gated Channels Open and close for certain molecules Carrier molecules Aid in the movement of materials through the cell membrane Aquaporins Allow water to flow through The cell membrane is made of many smaller pieces that are held together and are always in motion Cells are organized internally. Plants, most bacteria, and fungi have a cell wall outside of the membrane. This wall of plant cells is made of a carbohydrate called cellulose. It gives the cell strength and rigidity If a plant cell absorbs too much water the membrane could burst, the cell wall helps to alleviate this. A cell needs to gain things from the atmosphere, it can not be totally separated. Water, oxygen, nutrients must pass through the membrane of the cell Waste products must get out of the cell Molecules can enter or leave the cell through either ______________or ___________________ Moving a molecule from an area of low concentration to an area of high concentration requires energy Like going uphill Need energy in the form of ATP to transport molecules Desert plants do this to gain water Example of a concentration gradient in lungs Number one active transport system in the body Without it, our response time would be even slower than it already is Pump moves 3 Na ions out of the cell and 2 K ions into the cell against the concentration gradients ▪ Leads to an electrochemical gradient across the cell membrane that is important for nerve impulses and resulting movement Two types of proteins that help One protein extends through the membrane Another protein is imbedded at the glycerol layer Some act as carrier molecules that allow the passage of only one type of molecule These can open and close to create a bigger gap or are shaped specifically for that type of molecule This type of movement is called facilitated movement Molecules are always in _______________ Like bumper cars. Everything moves until it is evenly distributed. Like a juice. Same amount of flavor everywhere in the bottle. When the concentration in one area is higher than another the molecules will move from areas of high concentration to areas of low concentration to even out the distribution. It requires no outside energy source ▪ Like sledding downhill One of the most important molecules to diffuse in and out of the cell is water. Without it cannot have homeostasis Endocytosis Cell membrane slowly wraps around a molecule or another cell and pulls it inside ▪ White blood cell and bacteria Phagocytosis = ingestion of solids into the cell through endocytosis Pinocytosis = the ingestion of liquid into the cell through endocytosis Exocytosis When a cell membrane gets rid of waste or protein that has been packaged by the golgi body by unwrapping around it There are both organic and inorganic substances in cells that are involved in reactions Some molecules are too big to enter the cell They are broken down through the process of _________________________ Proteins are broken down (digested) into smaller molecules known as _______________________________ Starches are digested into _______________________________ We need to digest things because only the smaller molecules (amino acids and simple sugars) can enter a cell or blood vessel When molecules come together and form building blocks of compounds that we need to live. This process is known as _____________________ The building blocks are made into complex things Like proteins, starches, DNA… Not all nutrients are used in building blocks. Some nutrients are broken down even more for the energy that is stored in the bonds. This process is _____________________________ Some proteins in the cell membrane can receive chemical messages from other cells. These molecules are called receptor molecules. These are how cells communicate between themselves. Chemicals made in the endocrine glands, ____________________, and other chemicals made by nerve cells are the communication between cells in the body If the hormones/signals are blocked then homeostasis can be affected. Plants Cell Wall Chloroplasts Large Vacuole Middle Lamella Animals None None Lysosomes None Cells have specialized structures known as _________________, undergo special functions. We can organize cells into specialized structures Complex organisms have several advantages over simple organisms The structural organization of organisms is shaped like a pyramid A single cell in a complex organism cannot accomplish much. Cells are grouped into _____________to expand their function. Example: A single muscle cell cannot move an organism but a group of them can Different tissues are combined to form an ________________ that performs the life process. Several organs can work together to form an ___________________________________ that performs one of the life processes. ▪ Example: The heart is an organ, it pumps blood. The heart is part of an organ system that transports materials throughout the body Highly complex They require multiple organs, systems and complete life processes All the organs must interact to stay alive Have specialized cells Digestive systems, respiratory system, circulatory system, excretory system, movement, coordination, immunity, and reproduction are all needed One-way passage Mouth, stomach, intestines and other organs Food enters the body through the mouth, broken down mechanically by chewing and chemically by saliva Moved through the body by muscle contractions The very small molecules in food can pass through cell membranes to be used as nutrients the rest of the food is eliminated from the body as waste Respiration uses oxygen to break down molecules (from food) to release energy The respiratory system exchanges gases between the blood and the environment Takes in oxygen for cell respiration and transfers it to the blood Removes carbon dioxide – Waste from cell respiration – from body through the blood Lungs and nose do most of work Involves movement of molecules into the cell and between cells Function = transport materials throughout the body Carries digested food and oxygen to the cells Carries waste from the cells to the lungs, kidneys and skin to be excreted Blood vessels carry chemical messengers (hormones) and proteins to attach foreign substances to give the body immunity (antibodies) Includes the heart, blood vessels, and blood The removal of waste produces from cells of the body Includes lungs, kidneys, and sweat glands in the skin The body moves due to interaction of muscles and bones The muscular and skeletal systems work together to provide movement and support for the body Allows body to avoid danger, find food, mates, and shelter Nervous system and endocrine system control coordination of the body’s activities The systems work together to send messages to cells throughout the body The nervous system sends signals along nerves The glands of the endocrine produce chemical messengers (hormones) to travel in blood The brain and nerves are part of the nervous system The endocrine has glands – pancreas, ovaries, testes The ability to resist disease White blood cells of the immune system engulf and destroy invading bacteria or viruses by digesting them Others protect the body against specific foreign invaders Organisms produce new organisms of the same kind Releases sex cells and hormones that are needed for the creation of offspring and then its development Human reproduction allows for sexual (not asexual) reproduction Allows two people to create an offspring that is not identical to either parent The organ systems in the body are continuously interacting Examples: Nutrients from digestive system are transported to the cells through the circulatory system Reproductive system is regulated by hormones from the endocrine system Body temperature drops, nerves in the brain signal the muscles to shiver, generating warmth Blood sugar is constantly regulated by hormones to keep it balanced. If one organ system is not working right then the entire organism could fail. Because it is not maintaining homeostasis Example: If the heart does not beat correctly, the cells all throughout the body will not get oxygen and fail causing death Single-celled organisms are much less complex than multicellular organisms A paramecium is a single celled organism that uses a food vacuole (organelle) to digest food. It does the same function as the human digestive system Function Single Cell Gas Exchange Cell membrane Transport of substances Nutrition Cytoplasm Excretion Specialized vacuoles Cell membrane Multicellular Organism Respiratory system Circulatory system Digestive system Excretory system There are major similarities between humans and other organisms Examples: All organisms are made mostly of carbon, hydrogen, oxygen and nitrogen. ▪ They form carbohydrates, proteins, and other organic molecules Humans are made of different kinds of cells, like muscle, nerve, and blood cells. These cell types are the same in other complex organisms. The organ systems and physical characteristics in humans are very similar to other complex organisms. Everything from the earthworm and up has a complex digestive tract for breaking down food. Pig hearts are so similar to humans they can be used for transplants. Reproduction is also very similar. Everything from Fish, amphibians, reptiles, and birds reproduce sexually where an egg and a sperm combine Humans have the same kind of genetic information as everything else. Everything from bacteria on, have DNA as their genetic material.