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Transcript
DNA Computer Review
I.
Mitosis vs Meiosis
a. Go to http://www.pbs.org/wgbh/nova/miracle/divide.html
b. Click on “Go to mitosis vs. meiosis”
c. Define:
i. Centrioles;
ii. Spindle Fibers
d. Work through the animation and fill in the chart:
Mitosis
Meiosis
Where does it occur
Starts with
Ends with
Chromosome # (beginning
vs end)
Genetic Variation?
e. Looking at the full processes, how does meiosis look different than mitosis?
II.
DNA Structure/Replication
a. Go to http://library.med.utah.edu/NetBiochem/pupyr/pp.htm
b. What are the 3 parts of a nucleotide? ______________________________
c. Which of the 4 nitrogen bases are purines?
Pyrimidines?
d. Adenine bonds with? ____________
Cytosine bonds with? ______
e. What holds the nitrogen bases together?
f. Go to http://nobelprize.org/educational_games/medicine/dna_double_helix/
g. Click on “Play the DNA-doube heix game”
h. What needs to happen first for DNA replication to occur?
i. When does DNA replication occur?
j. Give the complementary DNA strand for the following:
ATCACTGGACTGACTGACCC
III.
DNA vs RNA
a. Go to http://academic.brooklyn.cuny.edu/biology/bio4fv/page/molecular%20biology/dnastructure.html
b. Go to http://www.accessexcellence.org/RC/VL/GG/rna2.php
c. List 3-4 differences that DNA and RNA have
d. Go to http://library.thinkquest.org/04apr/00217/en/biology/rna/index.html
e. List the function of each type of RNA
i. mRNA
ii. tRNA
iii. rRNA
IV.
Replication vs Transcription
a. Go to http://www.fed.cuhk.edu.hk/~johnson/teaching/genetics/animations/dna_replication.htm
b. Go to http://www.fed.cuhk.edu.hk/~johnson/teaching/genetics/animations/transcription.htm
V.
Transcription
a. Go to http://www-class.unl.edu/biochem/gp2/m_biology/animation/gene/gene_a2.html
b. What happens during transcription? ______________________________
____________________________________________________________
c. Where does transcription occur?
d. Transcribe the following DNA strand:
ATCGATTTGCAACCAGGAAG
VI.
Translation
a. Go to http://www.courses.fas.harvard.edu/~biotext/animations/TRANSLATE20b.swf
b. What do tRNA’s do?
c. What part of the tRNA binds to the codons of the mRNA?
d. Go to http://learn.genetics.utah.edu/content/begin/dna/transcribe/
e. Go to http://www.biostudio.com/demo_freeman_protein_synthesis.htm
f. Go to http://library.thinkquest.org/20465/g_DNATranscription.html
g. Go to http://www.wisc-online.com/objects/index_tj.asp?objID=AP1302
h. Give the following information based on this DNA strand:
DNA:
TAC-GGG-CAT-CGC-AAC-ACG-TTA-TAG-ATT
i. mRNA:
ii. tRNA’s:
iii. protein:
i. What type of bond holds amino acids together in a protein?
j. Where does translation occur?
VII.
Mutations
a. Go to http://highered.mcgrawhill.com/sites/0072556781/student_view0/chapter11/animation_quiz_3.html
b. Go to http://highered.mcgrawhill.com/sites/0072556781/student_view0/chapter11/animation_quiz_4.html
c. Go to http://staff.jccc.net/PDECELL/evolution/mutations/mutation.html
d. Define the following:
i. Missense mutations:
ii. Nonsense mutations:
iii. Silent mutations:
iv. Substitution mutations:
v. Frameshift mutations:
vi. Translocations: