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Suggested Answers to Discussion Topics, Chapter 37, Thyroid and Parathyroid Agents Suggested Answers for Discussion Topics 1a. Students’ answers should include the following: Thyroid hormone is responsible for the regulation of metabolism. Students should list some of the signs of hypothyroidism and related them to Mrs. Smith’s age and lifestyle. Thyroid hormones affect or regulate most major body functions. Growth and development are dependent on thyroid hormones. Calcium levels are regulated by the thyroid gland. Learning Objective(s) 2, 3, 4, 5 1b. Students’ answers should include the following: Levothyroxime is a synthetic salt of T4 used for thyroid hormone replacement. Bioavailability and reliability are predictable and stable. Levothyroxime increases metabolism and improves the overall rate of metabolism of fat, protein, and carbohydrate, improving growth and maturation. 1c. Students’ answers should include the following: Key concept: if the medication dosage is correct, there should be few, if any, adverse effects. The most common adverse effects result from cardiac stimulation and CNS stimulation. 2a. Students’ answers should include the following: Students should use Box 37.4 as a guide to answer this question. Aerobic exercise: this can be as simple as walking 10 minutes a day. This does not have to be high impact. Proper diet: protein and calcium are essential for bone growth. Protein should be eaten two to three times per week. Weight loss can decrease pressure on bones at rest. Hormone replacement therapy: risk-versus-benefit concept. Studies have shown an increased risk of cardiac disease in women on HRT. 2b. Students’ answers should include the following: Osteoporosis results from a lack of bone-building cell (osteoclast) activity. There is a decrease in bone matrix and mass with less calcium and phosphorus being deposited in the bone. Women after menopause are at risk but also patients of any age who are nonweight bearing, patients who have malnutrition, and patients with limited physical activity. 2, 3, 4, 5