Download D. Jewish or Middle Eastern

NAME _____________________________ f13
Chapter 14 –HONORS GENETIC DISORDERS TEST
(2 points each)
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causing red blood cells to
change shape leading to circulatory problems
A. ACHONDROPLASIA
B. HUNTINGTON’s
C. COLORBLINDNESS
D. TAY-SACHS
E. HEMOPHILIA
F. SICKLE CELL DISEASE
G. CYSTIC FIBROSIS
H. PHENYLKETONURIA
I. TURNER SYMDROME
J. DOWN SYNDROME
K.KLINEFELTER SYNDROME
L. DUCHENNE MUSCULAR
DYSTROPHY
________
Degenerative brain disorder caused by extra CAG repeats
whose symptoms appear around middle age and result
in nursing home care and eventual death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in blood clotting proteins so individuals can’t stop
bleeding if injured
_______
Inability to break down the amino acid phenylalanine
which accumulates in the brain causing mental retardation
_______
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue resulting in paralysis and early death
_______
Syndrome in which a person has three #21 chromosomes causing
characteristic facial features, mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy)
_______
Defect in ion channels which transport Cl- ions causing mucous to build up
in lungs and digestive organs
_______
Enzyme defect that causes lipids to build up in the brain;
Resulting in blindness, mental retardation, and death by age 5
_______
Defect in bone formation resulting dwarfism
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causing red blood cells to
change shape leading to circulatory problems
A. SICKLE CELL DISEASE
B. DOWN SYNDROME
C. COLORBLINDNESS
D. PHENYLKETONURIA
E. CYSTIC FIBROSIS
F. ACHONDROPLASIA
G. HEMOPHILIA
H. TAY-SACHS
I. TURNER SYMDROME
J. HUNTINGTON’s
K.KLINEFELTER SYNDROME
L. DUCHENNE MUSCULAR
DYSTROPHY
________
Degenerative brain disorder caused by extra CAG repeats
whose symptoms appear around middle age and result
in nursing home care and eventual death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in blood clotting proteins so individuals can’t stop
bleeding if injured
_______
Inability to break down the amino acid phenylalanine
which accumulates in the brain causing mental retardation
_______
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue resulting in paralysis and early death
_______
Syndrome in which a person has three #21 chromosomes causing
characteristic facial features, mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy)
_______
Defect in ion channels which transport Cl- ions causing mucous to build up
in lungs and digestive organs
_______
Enzyme defect that causes lipids to build up in the brain;
Resulting in blindness, mental retardation, and death by age 5
_______
Defect in bone formation resulting dwarfism
MULTIPLE CHOICE:
Tell how each of the following disorders is inherited:
_______
Achondroplasia
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Sickle Cell Anemia
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Hemophilia
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Tay-Sachs
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Down syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Colorblindness
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Duchenne Muscular Dystrophy
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Phenylketonuria (PKU)
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Cystic Fibrosis
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Turner syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Klinefelter syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Huntington’s
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
NAME _____________________________ (f13)
Chapter 14 –HONORS GENETIC DISORDERS TEST
(2 points each)
MULTIPLE CHOICE:
Put the letter of the answer that best completes the statement on the blank at the left.
_______ In humans an XX genotype makes you a ___________________
A. male
B. female
C. mutant
D. carrier
________
________
________
__________________ cell mutations happen in sperm or eggs and can be passed on to the
offspring.
A. body
B. somatic
C. germ
D. allele
____________________ mutations cause death, often before birth.
A. Somatic cell
B. X-linked
C. Germ cell
D. Lethal
__________________ cell mutations happen in body cells so they affect the organism itself,
but are NOT passed on to offspring.
A. Gamete
B. Somatic
C. Germ
D. Allele
_______ In humans an Xy genotype makes you a ____________________.
A. male
B. female
C. mutant
D. carrier
________
A gene that is carried on an X or Y chromosome is called ______________________.
A. sex influenced
B. sex linked
C. autosomal
D. lethal
________
The failure of homologous chromosomes to separate during meiosis is called ______________
A. nondisjunction
B. frameshift
C. crossing over
D. synapsis
________ A family record that shows how a trait is inherited
over several generations is called a ______________
A. karyotype
B. Punnett square
C. pedigree
D. periodic table
________ A person that has one copy of a recessive autosomal allele and does not express the trait but can
pass it on to his/her offspring is called a __________________.
A. mutant
B. carrier
C. hemophiliac
D. gene marker
________
_______________________ can be carriers for AUTOSOMAL RECESSIVE disorders.
A. Only males
B. Only females
C. Both males and females
________
_______________________ can be carriers for X-LINKED RECESSIVE disorders.
A. Only females
B. Only males
C. Both males and females
________
A human cell with 3 copies of a chromosome would have 47 chromosomes instead of 46.
This condition is called ____________________.
A. monosomy
B. disomy
C. tetrads
D. trisomy
________
_____________________________ twins have identical DNA.
A. monozygotic
B. dizygotic
C. fraternal
D. trisomic
________
This picture of an organism’s chromosomes is called a
______________________
A. pedigree
B. Punnett square
C. karyotype
________
The chromosomes that DO NOT determine sex are called ____________________
A. sex chromosomes
B. autosomes
C. gene markers
D. pedigree partners
________
Which parent determines the sex of the baby?
A. father
B. mother
________
The dense region in the nucleus of female cells that forms when one of the X chromosomes is
randomly inactivated is called a _____________________ body.
A. autosomal
B. sex-linked
C. nucleolus
D. Barr
________
Turner’s syndrome is an example of a _____________________ disorder.
A. trisomy
B. monosomy
C. somatic cell mutation
________
X-linked recessive disorders show up more frequently in ____________________.
A. females
B. males
________
Sickle cell disease is found more frequently in __________________________ populations.
A. Jewish
B. Caucasians
C. African American
________
Tay-Sachs disease is found more frequently in_________________________ populations.
A. male
B. Caucasion
C. African American
D. Jewish or Middle Eastern
________
Cystic fibrosis is found more frequently in _______________________ populations.
A. male
B. Caucasion
C. African American
D. Jewish or Middle Eastern
________
Which food
A.
B.
C.
D.
group must people with phenylketonuria avoid?
carbohydrates
proteins
lipids
polysaccharides
_________ This diagram shows a person with
A. Klinefelter syndrome
B. Down syndrome
C. Turner syndrome
_________
People who are heterozygous for the ________________ allele are resistant to malaria.
A. hemophilia
B. cystic fibrosis
C. sickle cell disease
D. Huntington’s disease
_________ Which genetic disorder can be found in a pedigree showing the royal families of Europe?
A. Huntington’s
B. Tay-Sachs
C. Achondroplasia
D. Hemophilia
*
*
*
*
*
*
*
*
*
*
*
*
*
*
Match the symbol letter with the correct description
This diagram shows how an autosomal recessive trait is passed in a family.
Which member of this family shows the trait?
A
B
C
D
E
F
Which member of this family is a male carrier for this trait?
A
B
C
D
A and E in the diagram above are __________________
A. males that don’t show the trait
B. females that don’t show the trait
C. males the show the trait
D. females that show the trait
B and D in the diagram above are __________________
A. normal males
B. carrier males
C. diseased females
D. carrier females
E
F
*
HONORS BIO Human Genome TEST
NAME _____________________________
EXTRA CREDIT-BONUS
Think about it:
Several genetic disorders you learned about result from the inability to break down some molecule.
Which cell part do you think has lost its function?
_________________________
Name the autosomal recessive disorder carried on chromosome #21 mentioned in your book, which
is named after a famous athlete who had the disorder.
__________________________________________
Tell how the disorder shown at the left is inherited
(HINT- look at A) Circle one
Autosomal recessive
HONORS BIO Human Genome TEST
Autosomal dominant
X-linked recessive
NAME _____________________________
EXTRA CREDIT-BONUS
Think about it:
Several genetic disorders you learned about result from the inability to break down some molecule.
Which cell part do you think has lost its function?
_________________________
Name the autosomal recessive disorder carried on chromosome #21 mentioned in your book, which
is named after a famous athlete who had the disorder.
__________________________________________
Tell how the disorder shown at the left is inherited
(HINT- look at A) Circle one
Autosomal recessive
Autosomal dominant
X-linked recessive