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Digestive System
ANATOMY AND PHYSIOLOGY
Function

The digestive system is the first organ system to develop in
animals.

This system allows animals to take in nutrients that provide it
with energy and materials necessary to grow and maintain
their bodies.

The digestive system is at it’s core a tube that starts with the
mouth and ends with the anus. This tube is called the
alimentary canal, also known as the gastrointestinal tract
(GI tract).

The GI tract travels through the pharynx, esophagus,
stomach, small intestine, and large intestine.

Accessory organs such as the liver, pancreas, gallbladder,
and salivary glands, secrete substances that help in the
chemical breakdown and absorption of food.
matching
Six Steps of
Digestion

1. Ingestion

2. propulsion

3. mechanical breakdown

4. chemical breakdown

5. absorption

6. defecation
Animation

Ingestion, the first step in the digestion process. The teeth and tongue
mechanically break down the food. Increasing it’s surface area. Saliva begins
the foods chemical breakdown.

Propulsion, swallowing and peristalsis – muscles in the esophagus contract to
push food down. This delivers food to the stomach.

Mechanical breakdown, occurs in the stomach, the churning actions therein
further reduce the food to smaller particles.

Chemical breakdown, in the stomach and small intestine requires enzymes
secreted by the secondary digestive organs. The food then becomes
chemically less complex, and easy to absorb.

Absorption, the small intestine and the large intestine absorbe the chemical
nutrients and send it to the bloodstream so that these resources can be sent to
the rest of the body.

Defecation, lastly, depleted of nutrients, the waste is removed from the body via
the rectum and anus.
The layers of the Alimentary Canal

Mucosa: is the innermost layer, and composed of mucus covered
epithelial cells. It lines the inner walls of the alimentary canal.

Submucosa: layer of irregular dense connective tissue, contains
blood vessels, lymphatic vessels, and nerves. Lymphatic vessels and
glands in the submucosa secrete substances that aid in the
digestion and absorption

Muscularis Externa: composed of two layers of smooth muscle this
layer propels food though the canal using peristalsis. Nerves run
between the two muscle layers.

Serosa: A thin slippery layer that surrounds the alimentary canal and
reduces friction between organs in the abdominal cavity.
Layers of the
Alimentary Canal

The cavity, empty space inside
the alimentary canal is called
the lumen.
Organs of the
Digestive System

Oral cavity:

Ingestion of food

Mechanical breakdown of food
(chewing)

Chemical breakdown of food

Propulsion of food.
Organs of the Digestive System

Nasal Cavity:

Separated from the oral
cavity via the palate. The
uvula which hags down
from the soft palate
prevents food from entering
the nasal cavity.
Organs of the
Digestive System

Teeth and gums:

The gums are known as the gingiva,
a soft tissue that covers the necks of
the teeth and the upper jaw and
mandible.

Children have 20 deciduous teeth

Adults have 32 permanent teeth.
Anatomy of the Tooth
Organs of the Digestive System

Salivary Glands:

Parotid: largest salivary glands, just in front of the ears.

Submandibular: near the lower law

Sublingual: under the tongue

Secrete saliva: Mostly water, contains mucus, antibodies, and several
enzymes. The enzymes help break down starches into simpler sugars and
begin the breakdown of fats.
Organs of the Digestive System

Pharynx:


The throat

3 Parts: nasopharynx, oropharynx,
laryngopharynx

Epiglottis: moves down to prevent food passing
into the trachea durring swallowing.

Propels food down into the esophagus

Swallowing x-ray
Esophagus:

Posterior to the trachea and heart

Passes through a hole in the diaphragm

Uses a muscular contraction known as
peristalsis to propel food
Major Organs of the Digestive
System: Stomach

Matching

Stomach

4 major regions: cardia, fundus, body, and pyloric region

The stomach twists and contracts to churn food and break it down
both physically and chemically before passing through the pyloric
sphincter into the duodenum of the small intestine.

3 muscle layers



Longitudinal muscle layer (up and down) – top layer

Circular muscle layer (around the stomach) – middle layer

Oblique muscle layer (diagonally) – Inner layer
The rugae (folds) can flatten out increasing the stomach’s volume.

A full stomach can hold about 2 liters or more.

the stomach churning food (ramen)

Artificial stomach
The mixture of gastric juice and food is known as chyme
Stomach lining

Stomach lining

Epithelia cells at the surface, covered in
mucus (mucus prevents our digestive juices
from eating into our own tissues)

Gastric juice is secreted from gastric pits –
controlled by the parasympathetic nervous
system

The cells surround gastric pits that lead down
into the gastric glands.

Mucus-secreting cells

Parietal cells secrete hydrochloric acid (HCl)
and intrinsic factor (helps the body absorb B12)

Chief cells secrete pepsinogen – activates
protein-digesting enzymes

Enteroendocrine cells – produce gastrin
(hormone) that stimulates the production of
more gastric juice.
Small Intestine

Named for it’s diameter not its length.

Longest segment of the GI tract at 6-7
meters

Most chemical breakdown of food
occurs in the small intestine

Parts of the small intestine


Duadenum – secretions from the liver,
gallbladder, and pancreas enter the
duadenum from the duadenal ampulla

Jejunum (8 feet)

Ileum (12-13 feet)
Chemical digestion, absorption, and
propulsion via peristalsis occurs in all 3
regions.
Lining of
the Small
Intestine

Circular folds,
villi, and
microvilli all
greatly
increase the
surface area
of the lining of
the small
intestine.

Intestinal
crypts are
similar to
gastric pits.
Chemical Breakdown in the Small
Intestine.

When chyme enters the duodenum, secretions from the pancreas
and bile from the gallbladder are secreted, to help break down the
food.

Bile is important in the emulsification of fats.

The pancrease secretes many chemicals

Bicarbanate: to neutralize the acidic chyme

Pancreatic amylase: breaks down starches into disaccharides (2-sugar
molecules)

Pancreatic lipase: chemically breaks down lipids and fats. The emulsification
caused by the bile salts increases the surface area of the lipid, allowing more
of the pancreatic enzyme to work on the lipids at one time.

Pancreatic proteases: Breaks down protein, stays inactive until it enters the
small intestine. This protects the pancreas from being digested by it’s own
enzymes.
Absorbtion

Epithelial cells in the villi freely absorb monosaccharaides and
amino acids and transports them into the blood vessels in the villus.
This nutrient rich blood is collected and sent to the liver.

Free fatty acids also enter the epithelial cells and get repackaged
for transport.

B12 binds to intrinsic factor which will bind to receptors in the ileum.
This will allow the celss to absorb the large molecule.

Vitamins A, D, E, and K are absorbed with fats.
Major Organs of Digestion: Large
Intestine

Large diameter, shorter length.

Mostly propels waste and
absorbs water.

Contains colonies of bacteria
that live with us symbiotically.
They help us with the synthesis of
some B vitamins and vitamin K.

The cecum: where the ileum
empties into the large intestine.
The ileocecal valve opens in
response to gastrin produced by
the stomach.

The appendix protects the body
from infectious organisms.