Download What is the nutrient? Selenium. What is the RDA/DRI for the nutrient

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

Document related concepts

Plateau principle wikipedia, lookup

Drug interaction wikipedia, lookup

Neuropharmacology wikipedia, lookup

Pharmacogenomics wikipedia, lookup

Gastrointestinal tract wikipedia, lookup

Plant nutrition wikipedia, lookup

Selenium wikipedia, lookup

Transcript
1.
What is the nutrient?
Selenium.
2.
What is the RDA/DRI for the nutrient?
Recommended Dietary Allowances (RDAs) for Selenium
Age
Male
Female Pregnancy Lactation
Birth to 6 months 15 mcg* 15 mcg*
7–12 months
3.
20 mcg* 20 mcg*
1–3 years
20 mcg 20 mcg
4–8 years
30 mcg 30 mcg
9–13 years
40 mcg 40 mcg
14–18 years
55 mcg 55 mcg
60 mcg
70 mcg
19–50 years
55 mcg 55 mcg
60 mcg
70 mcg
51+ years
55 mcg 55 mcg
How is the nutrient metabolized?
Absorption of selenium occurs in the duodenum and jejunum of the small intestine and occurs more
readily in conditions of deficiency. Excess selenium is excreted via urine. In the body, selenium is
stored as selenomethionine, and selenocysteine is the active form. Selenium is transported bound to
albumin and then later to α2-globulin.
4.
What are food sources of the nutrient?
Foods Rich in Selenium
Food
Cals
DRI/DV
Tuna (4oz)
147
223%
Shrimp (4oz)
135
102%
Sardines (4oz)
189
86.9%
Salmon (4oz)
158
78.3%
Turkey (4oz)
167
62.2%
96
57.7%
Chicken (4oz)
187
56.9%
Lamb (4oz)
350
50.7%
Scallops (4oz)
126
44.7%
Beef (4oz)
133
43.5%
Cod (4oz)
5.
What disease states alter the nutrients metabolism?
Crohn’s disease, Celiac disease, and other GI tract conditions, as well as the resection or surgical
removal of parts of the GI tract can impair the absorption of Selenium.
6.
What are the tests or procedures to assess the nutrient level in the
body?
Measure selenium or glutathione peroxidase amounts in serum, platelets, or erythrocytes or in whole
blood. Urine samples and toenail clippings may also aid in selenium level assessment.
7.
What is the drug –nutrient interactions?
Using dimercaprol together with selenium can cause injury to the kidneys. Selenium may slow blood
clotting. Taking selenium along with anticoagulant medications might increase the chances of bruising
and bleeding. Taking selenium, beta-carotene, vitamin C, and vitamin E together might decrease the
effectiveness of some medications used for lowering cholesterol.
8.
How is the nutrient measured?
The most commonly used measures of selenium status are plasma and serum selenium concentrations.
Concentrations in blood and urine reflect recent selenium intake. Analyses of hair or nail selenium
content can be used to monitor longer-term intakes over months or years.
9.
What is the Upper Tolerable Limits?
Tolerable Upper Intake Levels (ULs) for Selenium
Age
Male
Female Pregnancy Lactation
Birth to 6 months
45 mcg 45 mcg
7–12 months
60 mcg 60 mcg
1–3 years
90 mcg 90 mcg
4–8 years
150 mcg 150 mcg
9–13 years
280 mcg 280 mcg
14–18 years
400 mcg 400 mcg
400 mcg
400 mcg
19+ years
400 mcg 400 mcg
400 mcg
400 mcg
10. What
are the physical signs of deficiency?
Keshan disease, congestive cardiomyopathy caused by a combination of dietary deficiency of selenium
and the presence of a mutated strain of Coxsackievirus.
11. What
are physical signs of toxicity?
Acute selenium toxicity can cause severe gastrointestinal and neurological symptoms, acute respiratory
distress syndrome, myocardial infarction, hair loss, muscle tenderness, tremors, lightheadedness, facial
flushing, kidney failure, cardiac failure, and, in rare cases, death.
Works Cited
Draper, Richard. "Selenium | Doctor | Patient.co.uk." Patient.co.uk. N.p., n.d. Web. 23 Apr. 2014.
<http://www.patient.co.uk/doctor/Selenium.htm>.
"Selenium." The World's Healthiest Foods. N.p., n.d. Web. 20 Apr. 2014.
<http://www.whfoods.com/genpage.php?dbid=95&tname=nutrient#deficiencysymptoms>.
"Selenium." Dietary Supplement Fact Sheet: — Health Professional Fact Sheet. N.p., n.d. Web. 23
Apr. 2014. <http://ods.od.nih.gov/factsheets/Selenium-HealthProfessional/>.
"Selenium Effectiveness, Safety, and Drug Interactions on RxList." RxList. N.p., n.d. Web. 23 Apr.
2014. <http://www.rxlist.com/selenium-page3/supplements.htm#Interactions>.