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SUR 110 Medication Drug Cards MEDICATION: Norepinephrine TRADE NAME: Levophed GENERIC NAME: Norepinephrine CLASSIFICATION: Vasopressor (a medication that raises blood pressure) ACTION: This medication is used for short-term control of low blood pressure. Stimulates alpha-receptors in arterial and venous beds and beta 1 receptors of heart, resulting in peripheral vasoconstriction and stimulation of heart rate and contractility. Coronary vasodilation occurs secondary to enhanced myocardial contractility. ROUTE (IN SURGERY): IV DOSAGE (ADULT): IV 2 to 3 mL/min of 4 mcg base/mL solution (8 to 12 mcg/min); adjust to response. Higher concentration (up to 16 mcg/mL) may be used in fluidrestricted patients. Usual maintenance dose is 2 to 4 mcg/min, but higher doses and prolonged therapy may be needed. SIDE EFFECTS: (2 MOST COMMON AND 2 MOST SERIOUS): Hypotension; increased peripheral vascular resistance; decreased carbon monoxide; precordial pain; ventricular arrhythmias; reflex bradycardia. Gangrene (when infused into small vein); thyroid enlargement; irritation from extravasation; decreased urinary output. HOW IT IS USED IN SURGERY: This medication is used for short-term control of low blood pressure. http://www.reutershealth.com/atoz/html/Norepinephrine.htm