Download Review Guide Chapter 14

Name_______________________________________ Date______________________ Per___________
Review Guide Chapter 14 Bio-CP
Part A) TEXTBOOK QUESTIONS: pg. 363 (# 1-7; 13, 14, 29);
pg. 365 (#1-3). (Complete Sentences or “0” credit)
What do I need to know: know how to do Punnett Square problems—sex-linked! Know how to read/interpret pedigrees (all types) and
karyotypes.
Part B) Please answer the following questions on this handout.
1.
What is the difference between autosomes and sex chromosomes?
2.
What is a “homologous pair”?
3.
What 3 things can a karyotype tell you?
4.
How many autosomes are in a normal diploid human cell?______ How many sex chromosomes?___
5.
How many autosomes are in a normal gamete?_22__ How many sex chromosomes? __1__
6.
Define nondisjunction.
7.
List three disorders that can result from nondisjunction.
8.
Cystic Fibrosis is an autosomal recessive disorder. Describe how a person might inherit this disorder.
9.
Why are sex linked genes called “sex-linked genes”?
10. Explain how a Karyotype is created.
11. Explain why a father determine the sex of a child?
12. Explain why are X-linked traits more likely to be expressed in males than in females?
13. If a person has Turners Syndrome, are they male or female? (explain)
14. PKU is an autosomal recessive disorder which leads to mental retardation. If it is diagnosed early the patient can be put on a
special diet lacking the amino acid phenylalanine and the brain will develop normally. A couple has a baby that has been
diagnosed with PKU. What are the parent’s genotypes? What is the probability that their next baby will have PKU? (show
your work---P = healthy; p= have PKU)
15. An X-linked recessive gene (Xc) produces red-green colorblindness in humans. A normal woman whose father was colorblind
marries a colorblind man. What percentage of their children will be colorblind? (show your work—punnett square).
16. An X-linked recessive gene (c) produces red-green colorblindness in humans.
a. A normal woman (homozygous dominant) marries a color blind man. What percentage of their children will be colorblind?
(Do the cross to find out)
b.
A normal man who’s father was colorblind marries a color-blind woman. What percentage of their children will be colorblind?
(Do the cross to find out)
17. Cystic fibrosis is an autosomal recessive disorder among Caucasians. A young woman has a brother who has cystic fibrosis. The
woman visits a genetic counselor to find out whether she carries the gene for cystic fibrosis. Before performing any tests, what can
the counselor initially tell her about the probability that she carries the gene? (Do the cross…………you need to know the genotypes of
her parents)
18. Huntington’s Disease is autosomal dominant disorder (H). A man who is heterozygous for HD and a woman who is homozygous
recessive decide to have children. What is the likelihood that the children have HD? (show your work)
19. In dogs, there is a hereditary deafness caused by a recessive gene (d). A kennel owner has a male dog that she wants to use for
breeding purposes. The dog can hear, so the owner knows she is either ____________ or ___________. To determine the dogs
genotype, the owner can breed the dog to a deaf female (dd).
Draw a punnett square to illustrate these two possible crosses. In each case, what % of the offspring would be expected to be
hearing (can hear)? What % would be expected to be deaf?
(show your work!!!)
________% hearing
________% deaf
________%hearing
________% deaf
Try these monohybrid cross problems on blood types. For each cross, give genotypes and phenotypes.
20. A woman with type O blood and a man who is type AB are expecting a child. What are the possible blood types of the kid?
21. What are the possible blood types of a child whose parents are both heterozygous for the B blood type?
22. What are the chances of a woman with type AB blood and a man with type A blood having a child with type O?________
23. Determine the possible genotypes and phenotypes with respect to blood type of a couple who’s blood types are homozygous A
and heterozygous B.
24. Jill is blood type O. She has 2 older brothers with blood types A and B. What are the genotypes of her parents with respect to these
phenotypes?
25. A test was done to determine the biological father of a child. The child has blood type A the mother is blood type B. Man #1 has a
blood type of O and man #2 has blood type AB. Which man is the biological father?
Dihybrid Cross practice problems
***Remember to use independent assortment to figure out the gametes for these crosses!!! (FOIL)
26. Cross a person with a genotype of Ao+- with a person with a genotype of AB+-.
Possible gametes Ao+- _________, _________, _________, __________
Possible gametes AB+- _________, _________, _________, __________
Phenotypes of offspring: ______________________________________________________________
27. Cross a person with a genotype AB+- with a person who is oo+-
Phenotypes of offspring: ______________________________________________________________
28. Cross a person who is homozygous A homozygous positive with a person who is heterozygous B homozygous negative.
Genotypes of parents: ____________________, _____________________
Phenotypes of Offspring:____________________________
A
B
29. Analyze the karyotypes above.
a) Which karyotype is a girl?___________________ how do you know?________________
b) Which karyotype is a boy? ____________________ how do you know? _________________
C
D
Analyze the karyotypes above.
c) Which karyotype shows evidence that the individual has Klinefelter’s syndrome? _____How do you know?
d) Which karyotype shows evidence that the individual has Turner’s syndrome?______How do you know?
30. Fill-in the Genetic Disease table below. Use your textbook and the information provided by teacher.
Genetic Disorder
Turner’s Syndrome
Characteristics
Sickle Cell Anemia
Klinefelter’s Syndrome
Tay-sachs
Cystic Fibrosis
Hemophilia
Phenylketonuria (PKU)
Huntington Disease
Down Syndrome
Pedigree Practice! (Pedigree is for Colorblindness)
31. Is it possible for individual IV-2 to be a
carrier?______Why? ____________________________
32. What sex can ONLY be carriers of colorblindness?
______________
33. With this in mind, what kind of non-mendelian trait is
colorblindness? ______________________
34. Why does individual IV-7 have colorblindness?
______________________________________
35. Why do all the daughters in generation II carry the
colorblind gene? _________________________
36. Male IV 1 has colorblindness. Whom did he inherit the disorder from? _________ Why?________________________