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Gender differences in cardiac hypertrophic remodeling
Gender differences in cardiac hypertrophic remodeling

... and estrogen / progestin Replacement Study (HERS)” [30] and the “Women’s Health Initiative Clinical Trial “ suggest that hormone replacement therapy in postmenopausal women can increase the possibility of myocardial infarction, deep vein thrombosis and pulmonary embolism [31, 32]. Conversely, other ...
Update on resuscitation: The 2015 AHA Resuscitation guidelines
Update on resuscitation: The 2015 AHA Resuscitation guidelines

... ILCOR reviewed whether the use of multiple vasopressin bolusses versus multiple adrenaline doses made a difference in patient outcome (ROSC, good neurological outcome, survival to discharge). They also reviewed adrenaline and vasopressin in combination. In both these settings, they recommend against ...
Ratio of Peak Early to Late Diastolic Filling Velocity of Transmitral
Ratio of Peak Early to Late Diastolic Filling Velocity of Transmitral

... The prevalence of systemic hypertension in the Western world is approximately 25% [1] and its association with cardiovascular disease is well established. If left untreated, systemic hypertension may lead to progressive myocardial hypertrophy and left ventricular (LV) diastolic dysfunction [2–4], bo ...
PDF - Romanian Journal of Cardiology
PDF - Romanian Journal of Cardiology

... identifying mean PAP over 20 mmHg are 70% and 92% respectively, independently of body surface area and sex19. Although PAP is considered the main cause of PA dilation, the influence of other factors, such as time and flow, is less known. A recent study has shown that in patients treated for PH, the ...
Deciphering Cardiovascular Disease in ICD-10
Deciphering Cardiovascular Disease in ICD-10

... 3. Consider subacute as option in query to define acuity of ischemia. 4. Although some physicians include myocardial infarction with ACS or demand ischemia on a clinical basis, ICD-10 (like ICD-9) does not consider equivalent. Query if clinical indicators support myocardial infarction. ...
Coronary Effects of Very High-Dose Medical Radiation
Coronary Effects of Very High-Dose Medical Radiation

... during radiation therapy for certain malignancies (for example, breast cancer, Hodgkin's disease or other lymphomas). Such therapies, received in a series of doses over a period of weeks, can amount to internal radiation doses (all exposures combined) in the range of 1,000 to 5,000 rads, and even hi ...
Clinical guidance for the Management of patients with confirmed
Clinical guidance for the Management of patients with confirmed

... >60bpm & no heart block on recent ECG and systolic blood pressure > 100mmHg ...
Efficacy of Two Streptokinase Formulations in Acute Myocardial
Efficacy of Two Streptokinase Formulations in Acute Myocardial

... Background: We sought to evaluate the efficacy and safety of the different trade forms of streptokinase available in our country, namely Heberkinasa (Heberbiotec, Havana, Cuba) and Streptase (Aventis Behring GmbH, Marburg, Germany). Methods: We conducted a double-blind randomized clinical trial to c ...
Biventricular Pacemakers - Cardiac Resynchronization Therapy for
Biventricular Pacemakers - Cardiac Resynchronization Therapy for

... Evidence from clinical trials and systematic reviews supports the benefit of CRT treatment for patients with NYHA class III/IV heart failure. For this group, there are improvements in mortality, functional status and quality of life. As a result, CRT treatment may be considered medically necessary f ...
9 Evaluation and Emergency Treatment of Criticlly Ill Neonate
9 Evaluation and Emergency Treatment of Criticlly Ill Neonate

... smooth muscle gradually becomes thinner, and it resembles that of the adult by the time the baby is age 6 to 8 weeks. Most perinatal changes in hemodynamics are related to the thinning of the pulmonary vascular smooth muscle, resulting in a gradual fall in the PVR and a loss of RV dominance of the n ...
High Arteriovenous (AV) Access Flow and Cardiac Complications Hemodialysis
High Arteriovenous (AV) Access Flow and Cardiac Complications Hemodialysis

... Q. I am seeing congestive heart failure (CHF) in patients with borderline cardiac function and excellent fistulas. We have done compression studies on these patients during a cardiac cath by measuring the ejection fractions, then compressing the fistula with a blood pressure cuff and remeasuring t ...
Echocardiography in the Evaluation of a Hypertensive Patient: An
Echocardiography in the Evaluation of a Hypertensive Patient: An

Detecting B-Type Natriuretic Peptide to Better Diagnose Congestive
Detecting B-Type Natriuretic Peptide to Better Diagnose Congestive

... down, and swelling in that area reduces. Since CHF patients have a large amount of BNP, the receptors are unable to break down all of it and the swelling remains. Continual stress and swelling can be fatal. A way to measure the level of BNP in vivo could diagnose CHF before it becomes serious. Scien ...
Automatic External Defibrillators
Automatic External Defibrillators

... strategic locations on the chest of the victim and the power pack delivers a shock when a button is pushed. If effective, the shock restores normal electrical rhythm to the heart. An AED will not deliver a shock unless it first detects an abnormal heart rhythm. Where Are AEDs Located? AEDs are often ...
Prevention of Stroke in Nonvalvular Atrial Fibrillation
Prevention of Stroke in Nonvalvular Atrial Fibrillation

The study of the pulmonary circulation has, therefore, always at
The study of the pulmonary circulation has, therefore, always at

... of the procedure has been limited because of certain inherent difficulties. The analysis of air and blood samples is complicated, and collection of air samples demands intelligent cooperation on the part of the subject. The clinical usefulness of the procedure has also been restricted because the me ...
Defining Diastolic Dysfunction
Defining Diastolic Dysfunction

... therapeutic agents in the treatment of diastolic heart failure. Certain simple deficiencies of the Vasan-Levy classification could be easily addressed by the addition of appropriate exclusion criteria. If strictly applied, their definition of probable diastolic heart failure would include individual ...
EACPR Policy Statement  1 Referral order form for in-patient program.
EACPR Policy Statement 1 Referral order form for in-patient program.

... • Wound healing and exercise capacity should be considered [see also Table X] • To be started early in the in-hospital phase • In-patient and/or out-patients programs immediately after discharge lasting 8-12 weeks are indicated • Upper-body training can begin when the chest is stable, i.e. usually a ...
Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder

... evidence that ADHD medications raise the risk of sudden death even further, initiation of ADHD medication should be primarily at the recommendation of an ADHD specialist, although discussion of treatment choices with the responsible cardiologist is appropriate.” ...
Module 2 - Angelfire
Module 2 - Angelfire

... state of anesthesia is know as anesthetic induction. It is performed 10-20 minutes after premedication (Depending if IM or subQ) The patient normally has a decreasing state of consciousness during induction but there can be an excitement phase in the middle. ...
Rhythm v Rate Control, Circulation 2012
Rhythm v Rate Control, Circulation 2012

... Background—Stroke is a debilitating condition with an increased risk in patients with atrial fibrillation. Although data from clinical trials suggest that both rate and rhythm control are acceptable approaches with comparable rates of mortality in the short term, it is unclear whether stroke rates d ...
Chronic Stable Angina - Hellenic Journal of Cardiology
Chronic Stable Angina - Hellenic Journal of Cardiology

... 341 patients with mild to moderate stable angina and good left ventricular contractility, who were followed for 18 months and were treated either with angioplasty or with medication—the latter included 80 mg atorvastatin per day. The findings of the study showed that medication achieved a reduction ...
Inherited heart conditions Sudden arrhythmic death syndrome
Inherited heart conditions Sudden arrhythmic death syndrome

Myocardial infarction
Myocardial infarction

... skeletal muscle, but the MB fraction is much more specific for cardiac muscle: about 15 to 40% of CK in cardiac muscle is MB, while less than 2% in skeletal muscle is MB. The BB fraction (found in brain, bowel, and bladder) is not routinely measured. Thus, CK-MB is a very good marker for acute myoca ...
Poor Prognosis of Japanese Patients With Chronic Heart Failure
Poor Prognosis of Japanese Patients With Chronic Heart Failure

... Japanese CHF patients with an underlying MI is approximately 30%. The Framingham study revealed that the 2year survival rates of patients who had ischemia as an etiology of heart failure and survived 90 or more days after the onset of heart failure were 64% in men and 75% in women.7 Massie et al rev ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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