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Chronic Stable Angina - Hellenic Journal of Cardiology
Chronic Stable Angina - Hellenic Journal of Cardiology

... 341 patients with mild to moderate stable angina and good left ventricular contractility, who were followed for 18 months and were treated either with angioplasty or with medication—the latter included 80 mg atorvastatin per day. The findings of the study showed that medication achieved a reduction ...
16 A C S
16 A C S

... Angiotensin-converting enzyme (ACE) inhibitors, β-blockers, and aldosterone antagonists are all agents that slow down or reverse ventricular remodeling through neurohormonal blockage and/or through improvement in hemodynamics (decreasing preload or afterload).9 These agents also improve survival and ...
Cardiology
Cardiology

... valves are the structures that open and close with each heartbeat to ensure the proper sequence of blood flow through the heart. The tricuspid valve is located between the right atrium and right ventricle. The pulmonary valve opens from the right ventricle to the pulmonary artery. The mitral valve i ...
Colegio Interamericano de Radiología
Colegio Interamericano de Radiología

... (particularly scleroderma and CREST), congenital heart diseases and HIV infection. In portal hypertension, assessment prior to liver transplantation is essential as transplantation is contraindicated in case of PH in chronic liver disease 2. The aims of echocardiography in PH are: • Detection of ele ...
Physiologic risk assessment in stable ischemic heart disease
Physiologic risk assessment in stable ischemic heart disease

... patients with no significant coronary lesions was 91%, compared with 74%, 59%, and 50% for patients with one, two-, and three-vessel disease. Survival rate is known to further decrease in the presence of left main coronary artery disease and severe proximal left anterior descending stenosis.5 To pre ...
Aspirin Use for the Primary Prevention of Cardiovascular Disease
Aspirin Use for the Primary Prevention of Cardiovascular Disease

... The Task Force looked at the combined benefits and harms of taking aspirin for the primary prevention of both CVD and CRC. They found that aspirin can help prevent heart attacks and strokes in adults ages 50 to 69 who are at increased risk of CVD but who do not have an increased risk of bleeding. A ...
The Effect of Ramipril on Left Ventricular Mass, Myocardial Fibrosis
The Effect of Ramipril on Left Ventricular Mass, Myocardial Fibrosis

... Cats with CHF due to various cardiomyopathies often are treated with ACEI, but there is no clear evidence of their efficacy.b Treatment of cats with HCM in CHF with ACEI is routine, but such practice is based on personal experience and anecdotal evidence. Studies in cats with HCM and no clinical sig ...
Optimal Control Aspects of Left Ventricular Ejection - IME-USP
Optimal Control Aspects of Left Ventricular Ejection - IME-USP

... how the results of this optimal strategy differ from the established facts concerning, for example, the responses of the ventricle to different types of loading conditions. If the obtained results are at least qualitatively consistent with the system’s actual behaviour, then the approach may reveal ...
Women and Coronary Artery Disease
Women and Coronary Artery Disease

... of the heart, the muscle can die. Heart attacks are considered a medical emergency. Swift intervention is needed to prevent death. High blood pressure can cause hypertensive heart disease. When the walls of the heart are thickened, it causes the load of the heart to work less efficiently and harder. ...
Regional Myocardial Capillary Erythrocyte Transit Time in the
Regional Myocardial Capillary Erythrocyte Transit Time in the

... regional distribution of RBC transit times through the myocardial capillaries has not been previously measured. The present study was designed to measure the regional myocardial capillary RBC transit time by a new technique to determine whether there are regional differences in the capillary RBC tra ...
Atrial Fibrillation - CardiacAndVascular.com
Atrial Fibrillation - CardiacAndVascular.com

... especially during physical activity. For this reason people with atrial fibrillation have a decreased ability to exercise. Stroke is the major complication caused by atrial fibrillation. When blood does not completely empty out of the rapidly beating atria, a clot can develop in the blood that pools ...
O A
O A

... The chemotherapeutic agent 5-fluorouracil (5-FU) is a widely accepted part of many cancer treatment protocols. Its cardiotoxic potential is known, but considered uncommon and usually not life-threatening, although some cases of severe cardiotoxicity related to 5-FU have been reported. The objective ...


... endocrine cells per 10 cm of epithelium) [12]. However, with collapsed lung, crenation of the smaller airways occurs and the accuracy gained by application of these methods of quantification is largely lost, especially if attempts are made to express endocrine cells per 10,000 epithelial cells, when ...
Winter 2011/2012 - Heart and Vascular Services UCLA
Winter 2011/2012 - Heart and Vascular Services UCLA

... THV), sponsored by Edwards Lifesciences. This clinical trial, currently taking place at 5 Medical Centers in the U.S., will evaluate the use of another type of percutaneous valve, the Edwards Sapien valve, in the pulmonary position. The Sapien valve has the advantage of being a larger prosthesis tha ...
Predicting the Likelihood of Heart Failure with a Multi Level Risk
Predicting the Likelihood of Heart Failure with a Multi Level Risk

... develop predictive models that are able to predict the incidence of heart failure. The majority of these studies have used a binary output class, in which the prediction would be either the presence or absence of heart failure. In this study, a multi-level risk assessment of developing heart failure ...
PART 15 - Mike South
PART 15 - Mike South

... This baby was likely to have a cyanotic heart defect, as evidenced by his low saturations on pulse oximetry – both at rest and more so when crying. Minor desaturation (with saturations above 85%) may be difficult to detect clinically and Ryan might appear to be pink when he was comfortable. However, ...
Platelet function and long-term antiplatelet therapy in women: is
Platelet function and long-term antiplatelet therapy in women: is

... WHS, age was positively related to treatment effect, whereas a baseline cardiovascular risk profile was not:37 selective treatment of women .65 years of age yielded more net benefit than treating none, providing a 10-year number needed-to-treat to prevent one cardiovascular events .50.38 A recent tr ...
Word - The Open University
Word - The Open University

... Figure 1, CVDs are indicated in association with the particular body area where they mainly occur. It is useful to become more familiar with some of the more common terms that you will be encountering and their general definitions. To help you with any new medical terms, this course has an accompany ...
Delayed Clot formation R K Angle MA
Delayed Clot formation R K Angle MA

... process • Surgical bleed will not be detected • Adhesion defect will not be detected • Not sensitive for FVII deficiency • Not effective for monitoring of Warfarin/VKA’s • Standard TEG testing does not disclose increased bleeding risks due to treatment with acetyl salicylic acid or ADP receptor inhi ...
Myocardial ischemia and infarction
Myocardial ischemia and infarction

... Def.: Chronic reversible dysfunction of LV due to coronary disease, responding to inotropic stimuli. Residual contractile reserve can be demonstrated by them Could be presupposed in IM not explaining the degree of LV failure Histopathology: loss of sarcomeres, SR etc. 2 hypotheses: - original author ...
The roles of gender, the menopause and hormone replacement on
The roles of gender, the menopause and hormone replacement on

... gender distinctive, with lower b-myosin and higher sarcoplasmic reticulum Ca 21 ATPase expression in one study [81], and increased ACE expression in female pressure overloaded rats in another [82]. These gender differences in gene expression were not seen in control rats with no pressure overload. I ...
Changes in Ion Channel Gene Expression Underlying Heart Failure
Changes in Ion Channel Gene Expression Underlying Heart Failure

... The aim of the study was to investigate HF-induced changes in the expression of the ion channels and related proteins underlying the pacemaker activity of the SAN. Methods and Results—HF was induced in rats by the ligation of the proximal left coronary artery. HF animals showed an increase in the le ...
ventricular septal defect with pulmonary stenosis and - Heart
ventricular septal defect with pulmonary stenosis and - Heart

... due to a ventricular septal defect. Thus the withdrawal of occasional samples with a high oxygen content from the right ventricle is now interpreted as due to an inadequate mixing of the two streams of blood in this chamber, and not to the presence of pulmonary regurgitation. There was no evidence o ...
Snímek 1 - med.muni
Snímek 1 - med.muni

... disease, responding to inotropic stimuli. Residual contractile reserve can be demonstrated by them Could be presupposed in IM not explaining the degree of LV failure Histopathology: loss of sarcomeres, SR etc. 2 hypotheses: - original authors: chronic resting hypoperfusion, adaptive lowering of O2 c ...
Estimating coupling directions in the cardiorespiratory system using
Estimating coupling directions in the cardiorespiratory system using

... for diagnosing and assessment of diseases [1–3]. Different linear and nonlinear approaches have been applied for studying couplings within the cardiorespiratory system, such as spectral analysis [4–7], Granger causality [8,9], phase dynamics [10,11], conditional information [12,13], joint symbolic d ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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