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Coronary anatomy and left ventricular ejection fraction in patients
Coronary anatomy and left ventricular ejection fraction in patients

... cardiologists using a simplified scoring system derived from Dortimeter et al. [16]. Nine coronary segments were analyzed: the left main artery, four segments of the left descendent artery (proximal, middle, distal segment, and side branches), two segments of the circumflex artery, and two segments of ...
Impact of Longitudinal Myocardial Deformation on the Prognosis of
Impact of Longitudinal Myocardial Deformation on the Prognosis of

... decision.4,5 Consequently, myocardial contractility should be quantified by a sensitive and accurate method. In daily practice, systolic left ventricular (LV) contractility assessment is based on the LV ejection fraction (LVEF) measurement computed from apical views using echocardiographic imaging.6 ...
Left Ventricular Structural and Functional Changes in the Metabolic
Left Ventricular Structural and Functional Changes in the Metabolic

... patients with treated MS (92% diabetic) compared with controls showed a significant relationship between subclinical left ventricular systolic and diastolic dysfunction and the degree of metabolic burden; these changes were associated with reduced cardiorespiratory fitness.10 The effects of MS on ca ...
Heart Rate, Body Temperature and Physical Activity Are Variously
Heart Rate, Body Temperature and Physical Activity Are Variously

... 2002, Karasu et al. 1990). These data suggest that a mechanism that is intrinsic to the heart may partly underlie the bradycardia observed in ALX-induced diabetic heart. It should be noted however, that some studies have reported no effects of ALX on resting heart rate (Lee et al. 1989, Zola et al. ...
LA RM NELLA DIAGNOSI DIFFERENZIALE DELLA MIOCARDITE IN
LA RM NELLA DIAGNOSI DIFFERENZIALE DELLA MIOCARDITE IN

... and patchy, or alternatively diffusely subendocardial 1. LGE-CMR is a very established technique to image focal myocardial fibrosis in both ischemic and non-ischemic cardiomyopathies 2. Myocarditis is a challenging diagnosis due to the heterogeneity of clinical presentations, from acute coronary syn ...
C11.2 PPT - Destiny High School
C11.2 PPT - Destiny High School

... • Chapter 11 Lesson 1 vocab is on page 374. • You have 8 minutes to complete the worksheet. • Turn in the worksheet to Mr. B when you are finished. © Goodheart-Willcox Co., Inc. ...
Can a volume challenge pinpoint the limiting factor in a
Can a volume challenge pinpoint the limiting factor in a

... differentiation is crucial to direct adequate therapy. This study was set out to determine if a volume challenge could identify the limiting factor. Methods and study population Thirty-two catheterizations in 28 patients with a Fontan circulation were included. Pressures and oxygen saturations were m ...
Impact of Longitudinal Myocardial Deformation on the Prognosis of
Impact of Longitudinal Myocardial Deformation on the Prognosis of

... whole, SR values are less dependent of load conditions and may be superior to strain and velocity.10 Tissue Doppler imaging (TDI) is conventionally used to assess longitudinal myocardial velocity,11 whereas, for longitudinal strain and SR, speckle tracking appears to be less noised than TDIderived d ...
Mechanisms for increasing stroke volume during static
Mechanisms for increasing stroke volume during static

... have dual-chamber (right atrium and right ventricle) pacing and sensing pacemakers have been studied previously (1). When the patients exercised with the sensing feature of the pacemakers turned off and static exercise was performed with the HR fixed, SV increased and compensated for the lack of a c ...
Prognostic Significance of Right Bundle Branch Block in Patients
Prognostic Significance of Right Bundle Branch Block in Patients

...   The diagnosis of MI was established by the presence of 2 of the following 3 criteria: 1) elevation of serum creatine kinase (CK) to more than twice the upper limit of normal values, 2) characteristic chest pain lasting at least 30min. or 3) ECG ST-T changes with evolution of an abnormal Q wave. Cl ...
effect of training and 3 day bed rest
effect of training and 3 day bed rest

... steeper ...
Effects of the HeartMate II continuous
Effects of the HeartMate II continuous

... A number of studies have been designed to help predict those patients who are likely to present with RV failure after LVAD implantation.3– 6 Predictors of RV failure have been identified as female gender, nonischemic heart failure etiology, increased right atrial pressure, low pulmonary artery press ...
Relation of insulin to left ventricular geometry and function in African
Relation of insulin to left ventricular geometry and function in African

... has been validated by invasive and Doppler reference standards.26 Linear measurement– derived ejection fraction (EF) was calculated as the percent reduction of LV volume from diastole to end-systole. To estimate global LV EF, accounting for the contribution of each LV segment to systolic reduction o ...
Effect of aerobic conditioning on the peripheral circulation
Effect of aerobic conditioning on the peripheral circulation

... Subjects exercised on the cycle ergometer at two target work loads of300 and 700 kilogram -meters per minute (kgmlmin] . One minute was spent at a lower load for accli matization, followed by 3 minutes at the target load. During the last minute of exercise, heart rate and blood pressure were recorde ...
Inhaled Beta-2 adrenergic receptor agonists and
Inhaled Beta-2 adrenergic receptor agonists and

... and risk factors such as diabetes and smoking were more prevalent among cases than controls (Table 1). The relatively high prevalence of both coronary heart disease and asthma among controls was due to the stratified sampling of control patients and the restriction of both cases and controls to pati ...
Noninvasive acoustic blood volume measurement system for the
Noninvasive acoustic blood volume measurement system for the

... of the sensor (Fig. 6a) could not be accepted for use in the final POLVAD prosthesis. The main problem was the shape of the additional sensing chamber. It dramatically increased prosthesis height. The prosthesis should be implantable in the future, therefore it needs to be as compact as possible. Dur ...
NORADRENALINE (NOREPINEPHRINE) 1 MG/ML
NORADRENALINE (NOREPINEPHRINE) 1 MG/ML

... - Urinary system: retention of urine. - Respiratory system: respiratory insufficiency or difficulty, dyspnoea. - Locally: possibility of irritation and necrosis at the injection site. - E yes: acute glaucoma; very frequent in patients anatomically predisposed with the closing of the iridocorn angle ...
glucocorticoids activate cardiac mineralocorticoid receptors in
glucocorticoids activate cardiac mineralocorticoid receptors in

... and corticosterone possess similar high affinities for the MR, and glucocorticoids circulate at concentrations much higher than that of aldosterone under normal circumstances.6) Aldosterone action at MRs in epithelial tissues and vascular smooth muscle cells is ensured by the enzyme 11β-hydroxystero ...
Cardiac Resynchronization Therapy (CRT)
Cardiac Resynchronization Therapy (CRT)

... as well as it should. This means parts of the body don’t get enough blood and oxygen. Heart failure causes symptoms such as having less energy and being short of breath. These symptoms interfere with daily life. CRT (cardiac resynchronization therapy) is a treatment that may help. For many heart fai ...
Natural History and Prognosis of Atrial Septal Defect
Natural History and Prognosis of Atrial Septal Defect

... analyzed from the standpoint of the course and prognosis. The ages of the patients ranged from 18 to 67 years and the ratio of men to women was 1 to 2. Age distribution when compared with life expectancy tables indicated reduced life expectancy. Clinical analysis revealed that three quarters of the ...
Tumor Necrosis Factor - National Psoriasis Foundation
Tumor Necrosis Factor - National Psoriasis Foundation

... Patients with depression but lacking other inflammatory disorders have been observed to exhibit elevated concentrations of TNF-␣ and other cytokines (IL-1, IL-6, and CRP) in their blood. This is supported by Dowlati et al,69 who conducted a meta-analysis of 24 studies measuring cytokine concentratio ...
designer amphetamine - American College of Medical Toxicology
designer amphetamine - American College of Medical Toxicology

... Designer amphetamines produce many of the same effects as amphetamine. They can increase attention, cause anxiety, increase blood pressure and raise heart rate. Designer amphetamines may also produce some different effects based on their particular structure. Designer amphetamines often produce more ...
2016 ACC/AHA/HFSA Focused Update on New Pharmacological
2016 ACC/AHA/HFSA Focused Update on New Pharmacological

... Modernization—Processes have evolved over time in response to published reports from the Institute of Medicine (2, 3) and ACC/AHA mandates (4-7), leading to adoption of a “knowledge byte” format. This process entails delineation of a recommendation addressing a specific clinical question, followed b ...
Brain natriuretic peptide and optimal management of heart
Brain natriuretic peptide and optimal management of heart

... schedules may aid in avoiding fluid retention or alerting the patient to its presence. A regularly scheduled exercise program such as walk is recommended as it may have beneficial effects on symptoms. Smoking cessation is advised and moderation of wine intake is encouraged. Multi-drug therapy New gu ...
Obstructive sleep apnea characteristic in systolic heart failure patients
Obstructive sleep apnea characteristic in systolic heart failure patients

... compared mild-moderate Obstructive sleep apnea (OSA) patients to severe OSA cases in terms of demographic, clinical and polysomnographic variables. Of these 29 cases, three patients (10.3%) had mild OSA, while 6 patients (20.7%) were diagnosed with moderate OSA and severe OSA was determined in 15 (5 ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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