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24537
24537

... King Abdulaziz University Hospital on July 1983, attending clinics and in-patients, included in the on-call rota and carried out ward procedures such as bone marrow aspiration and biopsy, liver biopsy, pleural aspiration and biopsy, peritoneal tap central catheter, venous cut down, etc.  Passed the ...
Neurogenic atrial fibrillation
Neurogenic atrial fibrillation

... post-prandial states and alcohol are also precipitating factors.8 Vagally mediated AF rarely, if ever, progresses to permanent AF. A 24-hour ECG can confirm the role of the ANS by showing progressive slowing of the heart rate over a few hours, or even a few beats, before the onset of arrhythmia.3 An ...
Competing Risk of Cardiac Status and Renal Function During
Competing Risk of Cardiac Status and Renal Function During

... METHODS This study was an individual patient data analysis assembled from 6 prospective cohorts consisting of 1,232 patients hospitalized for ADHF. Endpoints were all-cause mortality and the composite of all-cause mortality and/or readmission for a cardiovascular reason within 180 days after dischar ...
Single Ventricle Physiology
Single Ventricle Physiology

... blood flow (relative to systemic blood flow) and therefore be in shock is:  a. Hypoplastic left heart syndrome  b. Tetralogy of Fallot with severe pulmonary stenosis  c. Tricuspid atresia with pulmonary atresia  d. Ebstein’s anomaly with functional pulmonary atresia  e. Asplenia with double out ...
Assessment of wasted myocardial work
Assessment of wasted myocardial work

... The main objective of the present study was to validate WWR and investigate changes in WWR to CRT in patients with heart failure and LBBB. ...
Right ventricular dysfunction in advanced heart failure
Right ventricular dysfunction in advanced heart failure

... tolerate volume overload than pressure ...
CCS Consensus Cover.qxd
CCS Consensus Cover.qxd

... Atrial fibrillation (AF) affects approximately 200,000 to 250,000 Canadians and is associated with many common clinical conditions such as aging, thromboembolism, hypertension, valvular heart disease and heart failure and is responsible for substantial morbidity and increased mortality. Consequently ...
Cardiac arrhythmias in coronary heart disease.
Cardiac arrhythmias in coronary heart disease.

... In patients with acute MI treated with thrombolytic therapy, new atrial fibrillation occurs in 7-10% of cases. The majority (70-100%) of these patients will be in sinus rhythm by the time of hospital discharge regardless of treatment strategy.35 In acute MI, atrial fibrillation occurs more commonly ...
methylene blue for cardiogenic shock.indd
methylene blue for cardiogenic shock.indd

... them) at the time the methylene blue infusion was started. In Table 1, we present the patient´s hemodynamic parameters before and during the administration of methylene blue. The SVR changed for all 3 patients during the administration of the drug. Figures 1-3 show the relationship between methylene ...
Systolic and Diastolic Heart Failure
Systolic and Diastolic Heart Failure

... Angiotensin receptor blocker • If ACE inhibitor is intolerable • Reduce all mortality • Monitor the renal function Medication Candesartan Valsartan ...
Experts` recommendations for the management of adult
Experts` recommendations for the management of adult

... cardiogenic shock complicating end-stage cardiac failure, post-shock treatment, various etiologies, and medical care pathway. The experts highlight the fact that CS is a rare disease, the management of which requires a multidisciplinary technical platform as well as specialized and experienced medic ...
Supraventricular Arrhythmias
Supraventricular Arrhythmias

...  1st line tx SVT  Diagnostic and tx for wide-complex SVT  RCTs: 60-80% termination with 6mg adenosine, 9095% after 12mg.  Use under cardiac monitoring with defibrillation pads in place (asystole or VF may result)  Don’t use in heart transplant ...
Right Heart Adaptation to Pulmonary Arterial€Hypertension
Right Heart Adaptation to Pulmonary Arterial€Hypertension

... is related to a decrease in flow reserve during exercise (decreased peak cardiac index) (22–24). In addition, a reduction in peripheral blood flow can increase lactate production, further contributing to muscle fatigue and exercise limitation. Supraventricular tachycardia, which can occur in approxima ...
Cardio85-CardiacMuscleMechanicsPt3
Cardio85-CardiacMuscleMechanicsPt3

...  Internal work is the work the heart does on itself with each heart beat such as muscle contractions and moving muscle components, such as ions in/out (Ca, Na, K).  Internal work is proportional to the area outside the loop o Looking at fig 12-16 in the notes, this would be the lightly shaded regi ...
Case 4. Coronary Heart Disease: Family History of Father with Early
Case 4. Coronary Heart Disease: Family History of Father with Early

... Lifestyle modification is beneficial for all patients with cardiac risk factors, even if drug treatment is also required. Measures include regular exercise; low-fat diet; and smoking cessation (see sections below on physical activity and diet). Drug treatment is an important component of the managem ...
Right Ventricular Geometry and Function in Pulmonary
Right Ventricular Geometry and Function in Pulmonary

... single photon emission computed tomography; STE: speckle tracking echocardiography; TAPSE: tricuspid annular plane systolic excursion. 1. Introduction Pulmonary hypertension (PH) is a rare disease which carries a poor prognosis [1,2]. Recent evidence showed that right ventricular (RV) function has a ...
HOW TO INSERT A PULMONARY ARTERY FLOATATION CATHETER
HOW TO INSERT A PULMONARY ARTERY FLOATATION CATHETER

... or intrapulmonary shunts, balloon rupture can be dangerous and in these cases only, carbon dioxide should be used. Injury to the heart valves during pulmonary artery catheterisation have been reported11. The catheter related sepsis rate is 0 to 2%. The pulmonary artery rupture have been reported aro ...
Urinary albumin excretion in heart failure with preserved ejection
Urinary albumin excretion in heart failure with preserved ejection

... The prevalence of patients with a positive UDT was 29.5% (n ¼ 728). Furthermore, the prevalence of patients with a positive UDT and with eGFR ,60 was higher (35.4%, n ¼ 386) than that of patients with a positive UDT and with eGFR ≥60 (24.9%, n ¼ 342). Among the positive dipsticks, the prevalence of ...
Robert Kloner, M.D., Ph.D.
Robert Kloner, M.D., Ph.D.

... remote ischemic conditioning (intermittent arm ischemia through four cycles of 5-min inflation followed by 5-min deflation of a blood-pressure cuff  The primary endpoint was major adverse cardiac and cerebrovascular events (MACCE)—a composite of all-cause mortality, myocardial infarction, readmissi ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... ronary arteries in coronary angiography was obtained. The etiopathogenesis of SCF is complicated and not yet fully understood. It is believed that some genetic and metabolic factors as well as microcirculation disorders, endothelium dysfunction, disseminated process of atherosclerosis as well as inf ...
Cardiac Arrhythmias and Stroke
Cardiac Arrhythmias and Stroke

... an increased incidence of stroke. There were, however, substantial differences between hypertensive men with and without frequent AEB. A high frequency of AEB was significantly associated with an increased risk. This association was independent of other major risk factors. Associations between AF an ...
Change in end-tidal carbon dioxide outperforms other surrogates for
Change in end-tidal carbon dioxide outperforms other surrogates for

... Background. During fluid challenge, volume expansion (VE)-induced increase in cardiac output (DVECO) is seldom measured. Methods. In patients with shock undergoing strictly controlled mechanical ventilation and receiving VE, we assessed minimally invasive surrogates for DVECO (by transthoracic echoc ...
Hyperoxia causes oxygen free radical
Hyperoxia causes oxygen free radical

... during a cardiac operation (1, 35). The original rationale for the use of hyperoxia was to ensure adequate oxygen delivery, assuming that higher levels of oxygen could only benefit the patient receiving critical care (6, 41). The potentially detrimental effects of hyperoxia itself were rarely consid ...
Cryptogenic Stroke
Cryptogenic Stroke

... Foramen Ovale for Secondary Stroke Prevention: 2010  No device for PFO closure after cryptogenic stroke has been approved by the FDA.  Randomized controlled trials offer the best means for assessing the safety and efficacy of percutaneous device closure relative to anti-thrombotic meds.  Enrollme ...
Association of Imaging Markers of Myocardial Fibrosis With
Association of Imaging Markers of Myocardial Fibrosis With

... Background—Metabolic and vascular disturbances contribute to diabetic cardiomyopathy, but the role of interstitial fibrosis in early disease is unproven. We sought to assess the relationship between imaging markers of diffuse fibrosis and myocardial dysfunction and to link this to possible causes of ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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