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Left Ventricular Mechanical Support with Impella
Left Ventricular Mechanical Support with Impella

... However, ECMO systems have device-related disadvantages such as hemolysis, coagulation disorders, and limited device durability. Furthermore, the efficacy of ECMO has been questioned with respect to the mechanoenergetic status of the heart.4,5 Adverse effects of ECMO on a failing heart are increased ...
Elisa Magosso, Silvio Cavalcanti and Mauro Ursino
Elisa Magosso, Silvio Cavalcanti and Mauro Ursino

... rerouted directly to the pulmonary arteries without the benefit of the normal right ventricle. In this situation the pulmonary and systemic circulation are in series with only one pumping chamber. Generally, patients who have undergone Fontan’s procedure have a good prognosis, although they have sub ...
PDF
PDF

... Background: Myocardial fibrosis (MF) is a risk factor for poor prognosis in dilated cardiomyopathy (DCM). Late gadolinium enhancement (LGE) of the myocardium on cardiac magnetic resonance (CMR) represents MF. We examined whether the LGE amount increases the incidence of adverse cardiovascular events ...
The Cardiovascular System The Cardiovascular System
The Cardiovascular System The Cardiovascular System

... Systemic venous pressure is much lower than arterial pressure. Although venous pressure ultimately depends on left ventricular contraction, much of this force is dissipated as blood passes through the arterial tree and the capillary bed. Walls of veins contain less smooth muscle than walls of arteri ...
Elevated plasma beta-endorphin levels in patients with
Elevated plasma beta-endorphin levels in patients with

... were treated with digitalis and diurclics . No patients had received adrenergic agonists or antagonists . Capiopril had been given to four patents and was withdrawn in two of them before this study . Patients with a recent myocardial infarction i<3 months) and symptomatic angina pectoris were exclud ...
Volume State Control - A New Approach
Volume State Control - A New Approach

... chapter in the physiology of the circulation.” How fateful do these words seem a century later. Another fifty years were to pass before Starr and Rawson4 postulated a role for Starling’s ‘mean systemic pressure’ in driving the venous return. It was Guyton who formalised this realisation into a quant ...
Ischaemic Heart Disease
Ischaemic Heart Disease

... risk factor (e.g. overweight, smoker, hypertensive, history of CVD etc). ...
the mechanism of intracardiac shunting in the lizard varanus
the mechanism of intracardiac shunting in the lizard varanus

... almost identical peak blood pressures in aortic arches and pulmonary artery, whereas in Iguana iguana (non-varanid Lacertilia) peak pressure in the aortic arches is about 50% higher than in the pulmonary artery (White, 1968). Pressure separation in varanids is even better, resulting in 2-5 to 3-5 ti ...
Cardiogenic Shock - The Association of Physicians of India
Cardiogenic Shock - The Association of Physicians of India

... especially when used in higher doses. Dopamine acts directly on myocardial β1-adrenergic receptors (Dose 5-10µg\kg\min)and acts indirectly by releasing norepinephrine. It has both inotropic and vasopressor effects, and its use is preferable in the presence of systolic pressures less than 80 mm Hg. T ...
Heart failure with systolic dysfunction complicating acute myocardial
Heart failure with systolic dysfunction complicating acute myocardial

... Nearly half of all patients with acute myocardial infarction (AMI) present left ventricular systolic dysfunction (LVSD) and one quarter show symptoms of heart failure (HF), both of which are associated with poor outcomes [1—6]. Nevertheless, the Global Registry of Acute Coronary Events (GRACE) has s ...
Pattern and severity of left ventricular diastolic dysfunction in early
Pattern and severity of left ventricular diastolic dysfunction in early

... cardiovascular mortality is more than 10 times higher cardiorenal connection. Chronic renal dysfunction in this population compared with an age, sex, and has a negative effect on cardiac function and chronic race matched population. [26] Data on kidney disease (CKD) is an important predictor of card ...
Lesson 33
Lesson 33

... What to Know About Physical Activity and Health Status 7. Helps older adults become stronger and better able to avoid falling Regular physical activity may help prevent accidents by improving muscular strength, balance, and reaction time. 8. Reduces the risk of cardiovascular diseases Regular physi ...
Blood Vessels
Blood Vessels

...  Baroreceptors adapt to chronic high or low blood pressure  Increased BP stimulates the kidneys to eliminate water, thus reducing BP ...
Printable PDF - The Gross Physiology of the Cardiovascular System
Printable PDF - The Gross Physiology of the Cardiovascular System

... equilibrium between the various extravascular compartments of the body and the cardiovascular space (Fig. 3). Changes in mean cardiovascular pressure result in shifts of fluid back and forth which tend to buffer sudden changes. This buffer system is fairly rapid but not instantaneous, as evidenced b ...
Bio_12_syllabus - Kingsborough Community College
Bio_12_syllabus - Kingsborough Community College

... The emphasis of this course will be concerned with understanding the structural and functional relationships of the major organ systems of the human body. A special effort will be made to understand the concept of homeostasis and how the individual organ systems of the body interact with each other ...
Soccer Training Improves Cardiac Function in Men with Type 2
Soccer Training Improves Cardiac Function in Men with Type 2

... SCHMIDT, J. F., T. R. ANDERSEN, J. HORTON, J. BRIX, L. TARNOW, P. KRUSTRUP, L. J. ANDERSEN, J. BANGSBO, and P. R. HANSEN. Soccer Training Improves Cardiac Function in Men with Type 2 Diabetes. Med. Sci. Sports Exerc., Vol. 45, No. 12, pp. 2223–2233, 2013. Introduction: Patients with type 2 diabetes ...
Bulking Up: The Dangers of Steroids
Bulking Up: The Dangers of Steroids

... people take when they use steroids? (Damage to the heart. Because it’s a muscle, the heart grows abnormally large. Blood pressure increases, and cholesterol levels are skewed—good cholesterol goes down and bad cholesterol goes up. These factors can result in heart disease, an accelerated or irregula ...
In fifteen (56%) patients, a relationship existed between P et CO 2
In fifteen (56%) patients, a relationship existed between P et CO 2

... of obtaining ROSC. These included averaging PetCO2 over 20 minutes of resuscitation, taking initial and maximal PetCO2, PetCO2 changes after ROSC and PetCO2 during resuscitation of various presenting rhythms such as asystole and PEA. Numerous studies illustrated that ROSC is associated with a sudden ...
PDF file
PDF file

... days, were consistent across a wide range of subgroups (Figure 4). A statistically significant p-value for interaction was observed for patients with heart rate ≥ 100 beats per minute at presentation, with a greater hazard in patients with higher heart ...
2016 ACC/AHA/HFSA Focused Update on New Pharmacological
2016 ACC/AHA/HFSA Focused Update on New Pharmacological

... Evidence (LOE) are derived independently of each other according to established criteria. The COR indicates the strength of recommendation, encompassing the estimated magnitude and certainty of benefit of a clinical action in proportion to risk. The LOE rates the quality of scientific evidence suppo ...
1 General IntroductIon  Pulmonary arterIal
1 General IntroductIon Pulmonary arterIal

... dyssynchrony might offer clinical benefit. In “left” heart failure (heart failure related to impaired left ventricular (LV) function), comparable therapeutic strategies have been demonstrated very successful in multiple large welldesigned clinical trials. The beneficial effects of β-blockers (often ...
Resistance training for chronic heart failure patients on beta blocker
Resistance training for chronic heart failure patients on beta blocker

... There is limited data in the literature reporting the effect of progressive resistance training on chronic heart failure patients in general and for those on beta-blocker medication in particular. Studies that examined the effect of resistance training on cardiac and chronic heart failure patients a ...
Atrial Flutter
Atrial Flutter

... an ambulatory setting if symptoms are non-specific and an arrhythmia is considered but has not been detected. Electrophysiological studies may be required at a later point for further diagnosis and therapy. ...
Reduce Infarct Size
Reduce Infarct Size

... Jennings et al 1960; Arch Pathol;70:68-78 Yellon DM and Hausenloy DJ 2007; N Engl J Med;357:1121-35 ...
Usefulness of Intra-aortic Balloon Pump Counterpulsation
Usefulness of Intra-aortic Balloon Pump Counterpulsation

... anyway, whether treated with IABP or any other additional therapy.29 It is unlikely that in these patients, any of the predefined end points like death or congestive heart failure would be reached anyway, irrespective if and how they were treated. This is corroborated by the systolic and diastolic bl ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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