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PDF - Medical Express
PDF - Medical Express

... of Medicine of Jundiaı́. Free and informed written consent form was obtained from all participants prior to their inclusion in the study. This is a prospective study of 20 consecutive patients with coronary artery disease subjected to coronary artery bypass grafting at Pitangueiras Hospital Jundiaı́ ...
Pulmonary Function Testing and Outcomes in
Pulmonary Function Testing and Outcomes in

Transmural Myocardial Infarction with
Transmural Myocardial Infarction with

... more major coronary arteries. However, small, clinically undetected or subendocardial infarctions not caused by occlusion of a major coronary artery have been reported at autopsy. Such infarctions usually were associated with other manifestations of illness such as aortic stenosis, pulmonary embolis ...
Transmural Myocardial Infarction with Arteriographically Normal
Transmural Myocardial Infarction with Arteriographically Normal

... more major coronary arteries. However, small, clinically undetected or subendocardial infarctions not caused by occlusion of a major coronary artery have been reported at autopsy. Such infarctions usually were associated with other manifestations of illness such as aortic stenosis, pulmonary embolis ...
Print - Circulation Research
Print - Circulation Research

... DISCUSSION ...
Thirst response to acute hypovolaemia in syncope Linköping University Post Print
Thirst response to acute hypovolaemia in syncope Linköping University Post Print

... which meant that they were unable to move their arms. Therefore, the researcher moved a pencil along the line and the volunteers stated where on the line they wanted the cross to be placed. The researcher who performed the thirst assessments during the experiments had no preconceived stance on thirs ...
Primary Percutaneous Coronary Intervention in an Acute Myocardial
Primary Percutaneous Coronary Intervention in an Acute Myocardial

... The European Society of Cardiology’s current guidelines on acute MI do not advocate performing angioplasty on non-culprit lesions in the setting of primary PCI. Nevertheless, multi-vessel angioplasty (including non-culprit lesions) may be reserved for patients suffering an acute MI when complicated ...
The striated muscles in pulmonary arterial hypertension: adaptations
The striated muscles in pulmonary arterial hypertension: adaptations

... and quadriceps muscles are reduced in PAH patients, a reduction that correlates with exercise capacity [7, 9, 44, 45]. Maximal muscle strength does not depend directly on oxygen supply, indicating that the intrinsic capacity of the skeletal muscle to generate force is impaired. Forearm grip strength ...
Ambulatory Monitoring for Heart Failure Patients – a Systematic
Ambulatory Monitoring for Heart Failure Patients – a Systematic

... 5. Cleland JG, Swedberg K, Follath F et al. The EuroHeart Failure survey programme-a survey on the quality of care among patients with heart failure in Europe. Part 1: patients characteristics and diagnosis. Eur Heart J 2003; 24: 442-463 ...
and Hanjörg Just Stavros Konstantinides, Annette
and Hanjörg Just Stavros Konstantinides, Annette

... were confined to isolated reports.2,3 During the past 15 years, the initial studies reporting noninvasive detection of right-toleft atrial shunt by contrast echocardiography4,5 were followed by extensive clinical research on the association between PFO and cryptogenic stroke.6 – 8 However, none of t ...
Telemetric Monitoring of Cardiovascular Parameters after Exercise
Telemetric Monitoring of Cardiovascular Parameters after Exercise

... has been shown that the rhythm of BP and HR may be controlled by an endogenous circadian oscillating system (34) in which the SCN plays an important role in rats (24). It is not completely understood how the circadian information from the SCN is modulated/ processed to regulate the 24h rhythm of BP ...
Copyright Information of the Article Published Online TITLE Renal
Copyright Information of the Article Published Online TITLE Renal

... 10 patients with mainly non-ischemic cardiomyopathies reveals a dramatic drop in arrhythmia burden after RDN[36]. Nonetheless, further prospective, randomized trials are needed to confirm this scope of application for RDN. Hemodynamics and volume changes: Since the effects of RDN on renal water/sodi ...
Biventricular Mural Thrombi in Patients With Dilated
Biventricular Mural Thrombi in Patients With Dilated

... The management of these patients mostly remains conservative, but surgical thrombectomy has been described along with myocardial revascularization. Patients with large LV apical aneurysms with thrombi and those who have refractory heart failure symptoms despite optimal medical therapy benefit from s ...
Correlation between Pulmonary Vascular Resistance and Some
Correlation between Pulmonary Vascular Resistance and Some

... variable in making determinations regarding cardiopulmonary diseases and can be measured echocardiographically. The objective of this report is to examine the relationship between echocardiographic parameters of ventricular function using PVR measurements. Materials and Methods: This study included ...
Cardiac Screening With Electrocardiography, Stress
Cardiac Screening With Electrocardiography, Stress

... In low-prevalence populations, even screening tests with high sensitivity and specificity are associated with a low positive predictive value (high rate of false-positive results) (59). Up to three quarters of asymptomatic men with exercise-induced ST-segment depression on ECG have no significant angi ...
092001 Cardiac Rehabilitation and Secondary Prevention
092001 Cardiac Rehabilitation and Secondary Prevention

... neurohumoral abnormalities,50 autonomic tone,50 and mitochondrial oxidative-enzyme activity in skeletal muscle.51 In a randomized, controlled trial, moderately intense aerobic exercise for one year improved patient-reported measures of the quality of life and reduced overall mortality and hospital-r ...
Cardiac Morphology and Blood Pressure in the Adult Zebrafish
Cardiac Morphology and Blood Pressure in the Adult Zebrafish

... the atrium (P ⬍ 0.05) with abundant mitochondria close to the sarcolemmal. Sarcoplasmic reticulum was sparse in zebrafish ventricle. Bulbus arteriosus was located anterior to the ventricle, and functioned as an elastic reservoir to absorb the rapid rise of pressure during ventricular contraction. Th ...
Acute Ischemic Stroke Management
Acute Ischemic Stroke Management

... help prepare nurses for the challenges the acute ischemic stroke patient may present during their emergency department and hospital stays. This course will assist nurses in the early recognition of acute ischemic stroke, and in reviewing cerebral artery anatomy, stroke scales, laboratory values, rad ...
Effects of physical exercises on the ventricular myocardium
Effects of physical exercises on the ventricular myocardium

... It is known that people who exercise regularly are less likely to develop heart diseases such as hypertension, obesity, diabetes mellitus, and dyslipidemia decreasing the occurrence of atherosclerosis and its complications: heart failure, stroke, and peripheral vascular disease. In the presence of p ...
Downloaded
Downloaded

... and investigated the presence of PPCM; in addition, they also examined PPCM patients and performed cardiac screening of their first-degree relatives. Their data suggest that a subset of PPCM is an initial manifestation of familial DCM and this was corroborated by the identification of a causative mu ...
Extreme sacrifice: sudden cardiac death in the US Fire Service
Extreme sacrifice: sudden cardiac death in the US Fire Service

Histamine H1 and H2 Receptor Gene and Protein Levels Are
Histamine H1 and H2 Receptor Gene and Protein Levels Are

... tive inotropic effect of histamine in left atrium, whereas H1 receptors are predominantly involved in the ventricle (Hattori et al., 1988, 1990, 1994). On the other hand, the positive inotropic effect of histamine in the human heart, whether in the atria or in the ventricle, is invariably blocked by ...
AHA Scientific Statement
AHA Scientific Statement

... better understand the cardiovascular risks for all drug products approved for ADHD. A review of adverse events of all stimulant products and atomoxetine occurred in early 2006 as described below. The importance of evaluating both methylphenidates and amphetamines, given that both are stimulants, was ...
A Case of Acute Myocarditis and Rhabdomyolysis after a Scorpion
A Case of Acute Myocarditis and Rhabdomyolysis after a Scorpion

... showed that scorpion venom may cause tachycardia and hypertension. The hypertensive and tachycardic situation suggests that our case was at the early stages. We believe that early initiation of medical treatment could prevent the progression of acute heart failure. The most common cause of death aft ...
A Case of Acute Myocarditis and Rhabdomyolysis after a Scorpion
A Case of Acute Myocarditis and Rhabdomyolysis after a Scorpion

... showed that scorpion venom may cause tachycardia and hypertension. The hypertensive and tachycardic situation suggests that our case was at the early stages. We believe that early initiation of medical treatment could prevent the progression of acute heart failure. The most common cause of death aft ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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