Full text - Nasjonalt kunnskapssenter for helsetjenesten
... the evidence for this endpoint to be moderate. Health related quality of life: Health related quality of life as measured with the Minnesota Living with Heart Failure Questionnaire both at 6 and 12 months was in favour of the intervention group. Mean and standard deviation were 45 (26) and 51 (25) a ...
... the evidence for this endpoint to be moderate. Health related quality of life: Health related quality of life as measured with the Minnesota Living with Heart Failure Questionnaire both at 6 and 12 months was in favour of the intervention group. Mean and standard deviation were 45 (26) and 51 (25) a ...
Acute Coronary Syndrome in Pre- and Post
... nutrients to the foetus. For this reason there is an increased erythropoiesis and plasma volume. Total body liquids, including plasma, increase by almost 7–8 litres. These changes result in about 50 % cardiac output increase.13 Secondly, during delivery heart work increases by 70–80 % due to either ...
... nutrients to the foetus. For this reason there is an increased erythropoiesis and plasma volume. Total body liquids, including plasma, increase by almost 7–8 litres. These changes result in about 50 % cardiac output increase.13 Secondly, during delivery heart work increases by 70–80 % due to either ...
Effect of Stimulation of Hypothalamus and Reticular Activating
... • The role of: the central nervous system in maintaining and modifying cardiac rhythmicity lias been extensively studied1"5 by many investigators. Emphasis has been laid on the diencephalic region as a pathway for important neurovcgetative fibers. Pitts et al." showed that from both sides of the hyp ...
... • The role of: the central nervous system in maintaining and modifying cardiac rhythmicity lias been extensively studied1"5 by many investigators. Emphasis has been laid on the diencephalic region as a pathway for important neurovcgetative fibers. Pitts et al." showed that from both sides of the hyp ...
Heart to Heart
... An inactive lifestyle is a risk factor for coronary heart disease. Regular, moderate physical activity helps prevent heart and blood vessel disease if done over a period of time. Regular exercise may also lead to improvement in other cardiovascular risk factors, such as weight loss, lower blood pres ...
... An inactive lifestyle is a risk factor for coronary heart disease. Regular, moderate physical activity helps prevent heart and blood vessel disease if done over a period of time. Regular exercise may also lead to improvement in other cardiovascular risk factors, such as weight loss, lower blood pres ...
Seminars in Cardiothoracic and Vascular Anesthesia
... challenge. Anesthesia is associated with depression of sympathetic activity, on which many patients with diminished cardiac reserve rely. In addition to this indirect effect, anesthetics interfere with cardiovascular performance, either by a direct myocardial depression or by modifying cardiovascula ...
... challenge. Anesthesia is associated with depression of sympathetic activity, on which many patients with diminished cardiac reserve rely. In addition to this indirect effect, anesthetics interfere with cardiovascular performance, either by a direct myocardial depression or by modifying cardiovascula ...
Academic Activites Physiology Dept. 2012
... Dr.Maulik S. Varu*, Dr.Anup M. Vegad*, Dr. Hitesh A. Jani**, Dr.Chirag V. Savalia***, Dr.Varsha S. Joshi**** * Assistant Professor, Department of Physiology, Govt Medical College, Bhavnagar, ** Assistant Professor , Department of Physiology, M. P. Shah Medical College, Jamnagar, *** Assistant Profes ...
... Dr.Maulik S. Varu*, Dr.Anup M. Vegad*, Dr. Hitesh A. Jani**, Dr.Chirag V. Savalia***, Dr.Varsha S. Joshi**** * Assistant Professor, Department of Physiology, Govt Medical College, Bhavnagar, ** Assistant Professor , Department of Physiology, M. P. Shah Medical College, Jamnagar, *** Assistant Profes ...
Is L-Carnitine Effective in Reducing Mortality After an Acute
... treatment, (p<0.05). The relative risk reduction (RRR) was -0.4%, so there was a 0.4% decrease in adverse events with L-carnitine versus placebo. The absolute risk reduction (ARR) is -10.4%, so there was a 10.4% decrease in adverse events with L-carnitine versus nothing. These values are small and f ...
... treatment, (p<0.05). The relative risk reduction (RRR) was -0.4%, so there was a 0.4% decrease in adverse events with L-carnitine versus placebo. The absolute risk reduction (ARR) is -10.4%, so there was a 10.4% decrease in adverse events with L-carnitine versus nothing. These values are small and f ...
Effect of Plethora and Hemorrhage on Left Ventricular Volume and
... it became of interest to determine the relationship between these factors and other circulatory factors in dogs subjected to a wide variation of EDV, ESV, and stroke volume such as occurs following plethora and hemorrhage. Since the applicability of Starling's law2 has never been studied in the inta ...
... it became of interest to determine the relationship between these factors and other circulatory factors in dogs subjected to a wide variation of EDV, ESV, and stroke volume such as occurs following plethora and hemorrhage. Since the applicability of Starling's law2 has never been studied in the inta ...
De Novo Acute Heart Failure and Acutely Decompensated Chronic
... Patients with hypoxemia (oxygen saturation below 90% by pulse oximetry) should be given supplemental oxygen (grade I recommendation, level C evidence). The goal is to raise the arterial oxygen saturation to at least 95%. In patients who also suffer from chronic obstructive pulmonary disease, the ris ...
... Patients with hypoxemia (oxygen saturation below 90% by pulse oximetry) should be given supplemental oxygen (grade I recommendation, level C evidence). The goal is to raise the arterial oxygen saturation to at least 95%. In patients who also suffer from chronic obstructive pulmonary disease, the ris ...
Regional patterns of cardiac sympathetic denervation in patients
... to different isotopes, better resolution with PET imaging and the ability to do absolute quantification with PET imaging. To the best of our knowledge no other group has studied cardiac sympathetic nerve destruction or dysfunction in diabetic patients using 11C-HED PET imaging. Cardiovascular autono ...
... to different isotopes, better resolution with PET imaging and the ability to do absolute quantification with PET imaging. To the best of our knowledge no other group has studied cardiac sympathetic nerve destruction or dysfunction in diabetic patients using 11C-HED PET imaging. Cardiovascular autono ...
C-Reactive Protein Levels in Chronic Congestive Heart Failure
... Background: Serum concentrations of C-reactive protein (CRP) are elevated in patients with congestive heart failure (CHF). However, clinical data about the prognostic value of CRP levels in patients with chronic stable CHF are sparse. We hypothesized that measurement of CRP might provide prognostic ...
... Background: Serum concentrations of C-reactive protein (CRP) are elevated in patients with congestive heart failure (CHF). However, clinical data about the prognostic value of CRP levels in patients with chronic stable CHF are sparse. We hypothesized that measurement of CRP might provide prognostic ...
Impaired left ventricular filling due to right-to
... filling state of the LV at end diastole, which is reduced because of an abnormal filling pattern. The main mechanism of LV underfilling was leftward interventricular septum displacement. Series vs. direct ventricular interaction. Impaired LV filling in RV pressure overload might be the result of two ...
... filling state of the LV at end diastole, which is reduced because of an abnormal filling pattern. The main mechanism of LV underfilling was leftward interventricular septum displacement. Series vs. direct ventricular interaction. Impaired LV filling in RV pressure overload might be the result of two ...
Beyond ejection fraction: an integrative approach for assessment of
... correlation with sonomicrometry data, is somewhat less loaddependent than LVEF,33,34 and may provide better insight into myocardial dysfunction in patients with preserved LVEF.35,36 Although the learning curve for Doppler-based deformation analysis is longer compared with LVEF, speckle tracking can ...
... correlation with sonomicrometry data, is somewhat less loaddependent than LVEF,33,34 and may provide better insight into myocardial dysfunction in patients with preserved LVEF.35,36 Although the learning curve for Doppler-based deformation analysis is longer compared with LVEF, speckle tracking can ...
POST-THESIS
... patients are not aware they even have CAD until their first heart attack3. The current standard of diagnosis, coronary angiography, is an expensive, risky, invasive, and time-consuming procedure. In order to detect the disease in early stages before there is a risk of myocardial infarction, a new me ...
... patients are not aware they even have CAD until their first heart attack3. The current standard of diagnosis, coronary angiography, is an expensive, risky, invasive, and time-consuming procedure. In order to detect the disease in early stages before there is a risk of myocardial infarction, a new me ...
Atrial Septal Defect Presenting in a 70-Year
... A 70-year-old female presented with a history of exertional breathlessness since 5 months, swelling of both lower limbs since 3 months, cough with expectoration since 1 month. The patient had no complaints before the last 5 months. She did not have any comorbidities, nor did she have a history of th ...
... A 70-year-old female presented with a history of exertional breathlessness since 5 months, swelling of both lower limbs since 3 months, cough with expectoration since 1 month. The patient had no complaints before the last 5 months. She did not have any comorbidities, nor did she have a history of th ...
Prognostic Impact of Diabetes Mellitus in Chronic Heart - J
... Background: It is unclear whether the prognostic impact of diabetes mellitus (DM) in chronic heart failure (CHF) is influenced by ischemic heart disease (IHD) and/or nephropathy. Methods and Results: We enrolled 4,065 consecutive patients with stage C/D CHF (mean age, 69.0 years; 68.7% male) in th ...
... Background: It is unclear whether the prognostic impact of diabetes mellitus (DM) in chronic heart failure (CHF) is influenced by ischemic heart disease (IHD) and/or nephropathy. Methods and Results: We enrolled 4,065 consecutive patients with stage C/D CHF (mean age, 69.0 years; 68.7% male) in th ...
Clinical and research issues regarding chronic advanced coronary
... The following report is based on a working group meeting about advanced coronary artery disease for patients with refractory ischemia who cannot receive revascularization. The aims were to review currently available treatment strategies, define unmet clinical needs, explore clinical trial design iss ...
... The following report is based on a working group meeting about advanced coronary artery disease for patients with refractory ischemia who cannot receive revascularization. The aims were to review currently available treatment strategies, define unmet clinical needs, explore clinical trial design iss ...
“Diastolic heart failure” or heart failure caused by - Heart
... correlate with the former measure.14 More important, reduced systolic AV plane displacement is a powerful predictor of poor prognosis.14 19 Indeed, it is worth noting that patients with an AV plane displacement of < 10 mm (that is, below our upper limit of normal) have a 25% mortality rate at one ye ...
... correlate with the former measure.14 More important, reduced systolic AV plane displacement is a powerful predictor of poor prognosis.14 19 Indeed, it is worth noting that patients with an AV plane displacement of < 10 mm (that is, below our upper limit of normal) have a 25% mortality rate at one ye ...
Myocardial Infarction and Stroke Risk in Young Healthy Men Treated
... and, for patients above 65 years, the level was 552 ng/dL (data not shown). Measurements of the mean total testosterone level could occur at the beginning, middle, or end of the injection cycle. As such, the range of total testosterone varied from 50 to 1600 ng/dL. However, the mean testosterone lev ...
... and, for patients above 65 years, the level was 552 ng/dL (data not shown). Measurements of the mean total testosterone level could occur at the beginning, middle, or end of the injection cycle. As such, the range of total testosterone varied from 50 to 1600 ng/dL. However, the mean testosterone lev ...
Drug-induced Torsades de Pointes in patients aged 80 years or more
... connexin43 (44). All these factors significantly increase the duration and the dispersion of repolarization to predispose a given patient to TdP when challenged with a drug that further impairs repolarization. For these reasons, it is well established that elderly female patients and patients with s ...
... connexin43 (44). All these factors significantly increase the duration and the dispersion of repolarization to predispose a given patient to TdP when challenged with a drug that further impairs repolarization. For these reasons, it is well established that elderly female patients and patients with s ...
Management of Mitral Stenosis - e
... heart disease in whom infective endocarditis prophylaxis remains recommended such as patients with prosthetic valves or prosthetic material used in valve repair, a drug other than penicillin is recommended to prevent infective endocarditis in patients receiving penicillin for rheumatic fever prophyl ...
... heart disease in whom infective endocarditis prophylaxis remains recommended such as patients with prosthetic valves or prosthetic material used in valve repair, a drug other than penicillin is recommended to prevent infective endocarditis in patients receiving penicillin for rheumatic fever prophyl ...
Diastolic Dysfunction and Anaesthetic Implications Dr S Kumar MD
... ventricular filling in patients with diastolic dysfunction. In patients requiring cardiac surgery, diastolic dysfunction has been shown to be a better predictor of haemodynamic instability than systolic dysfunction [15]. Moderate and severe diastolic dysfunction is also independently associated with ...
... ventricular filling in patients with diastolic dysfunction. In patients requiring cardiac surgery, diastolic dysfunction has been shown to be a better predictor of haemodynamic instability than systolic dysfunction [15]. Moderate and severe diastolic dysfunction is also independently associated with ...
PDF - Medical Express
... of Medicine of Jundiaı́. Free and informed written consent form was obtained from all participants prior to their inclusion in the study. This is a prospective study of 20 consecutive patients with coronary artery disease subjected to coronary artery bypass grafting at Pitangueiras Hospital Jundiaı́ ...
... of Medicine of Jundiaı́. Free and informed written consent form was obtained from all participants prior to their inclusion in the study. This is a prospective study of 20 consecutive patients with coronary artery disease subjected to coronary artery bypass grafting at Pitangueiras Hospital Jundiaı́ ...
Full Paper - Daniel Burkhoff MD PhD
... clamps are shown in Fig. 2. As shown in Fig. 2D, there is an approximately linear relationship (dotted line) between peak pressure and volume on the three isovolumic beats. The pressure-volume loop obtained on the ejecting beat “breaks through” that line, indicating an increased effective contractil ...
... clamps are shown in Fig. 2. As shown in Fig. 2D, there is an approximately linear relationship (dotted line) between peak pressure and volume on the three isovolumic beats. The pressure-volume loop obtained on the ejecting beat “breaks through” that line, indicating an increased effective contractil ...
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.