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Presentation Package
Presentation Package

... • Respiratory Responses – Blood Transport of Gases and Metabolic By-Products • Most oxygen in blood is carried by hemoglobin. • Most carbon dioxide removal is from its combination with water and delivery to the lungs in the form of bicarbonate. • During low- to moderate-intensity exercise, enough ox ...
Uremic autonomic neuropathy studied by spectral analysis of heart
Uremic autonomic neuropathy studied by spectral analysis of heart

... presence and severity of autonomic neuropathy (AN) do not seem to be related with either the duration of renal failure or with the duration of dialysis. In recent years, there has been an increased interest in the literature about autonomic nervous system function in chronic uremia, especially in th ...
PDF
PDF

... Approximately one-third of patients have LVOT obstruction at rest, and an additional onethird develop obstruction only after provocation with exercise or other hemodynamic stressors [7]. When this pathology is accompanied by persistent heart failure symptoms despite conventional therapies, patients ...
Improved reperfusion and clinical outcome with
Improved reperfusion and clinical outcome with

... fibrinolytic agent for evolving myocardial infarction. Yet, complete early reperfusion is achieved in only about a third of the patients[10], and reocclusion is observed in about 10% of patients in hospital[10] and in about one-third of patients at 3-months follow-up[11]. The addition of a low-molec ...
Aspirin for the Prevention of Cardiovascular Disease: U.S.
Aspirin for the Prevention of Cardiovascular Disease: U.S.

EFFECTS OF SUPINE AND-6 HEAD
EFFECTS OF SUPINE AND-6 HEAD

... influenced several central cardiovascular parameters. Astronauts first noticed that within a few hours of spaceflight their legs, particularly in the calf regions began to decrease in size. The Apollo-Soyuz Test Project was one of the first missions to make actual measurements of leg volumes and dis ...
Ventricular Tachycardia
Ventricular Tachycardia

... specific) Moss et al, Am J Cardiol 1999; Batra et al, J Pediatr 2002 LQT2: events triggered by auditory stimuli, such as an alarm clock or telephone ringing. Moss et al, Am J Cardiol 1999 LQT1/ LQT2: acute arousal events (such as exercise, emotion or noise) LQT3: highest risk of events when at rest ...
PDF
PDF

... Peripartum cardiomyopathy (PPCM) is a disorder in which initial left ventricular systolic dysfunction and symptoms of heart failure occur between the late stages of pregnancy and the early postpartum period. It is common in some countries and rare in others. The causes and pathogenesis are poorly un ...
Cardiovascular Assessment of Infants and Children INTRODUCTION
Cardiovascular Assessment of Infants and Children INTRODUCTION

... The clinical significance of the age of onset of congestive heart failure is as follows: 1. If a child becomes symptomatic due to congenital heart disease, there is a 95 percent probability that those symptoms will develop before 3 months of age and usually before 2 months. 2. Heart failure is rarel ...
Coronary Artery Disease - Philippine Heart Association
Coronary Artery Disease - Philippine Heart Association

... The statement “may be recommended” means that the procedure or treatment is useful or effective although with some conflicting evidence from other trials to trials conducted. The statement “not recommended or contraindicated” means that the procedure is not useful or effective and may be harmful bas ...
Complimentary Slide Presentation.
Complimentary Slide Presentation.

... associated with a 6% absolute (46% relative) reduction in the composite of death, reinfarction, recurrent ischemia, heart failure and shock ...
introduction - Surgical Critical Care. Net
introduction - Surgical Critical Care. Net

... septic shock (15). Norepinephrine is a more potent alpha1 agonist than dopamine and may be more effective at treating hypotension in patients with septic shock. Dopamine may be particularly useful in patients with compromised systolic function but causes more tachycardia and may be more arrhythmogen ...
Vasopressors and Inotropes in Shock
Vasopressors and Inotropes in Shock

... septic shock (15). Norepinephrine is a more potent alpha1 agonist than dopamine and may be more effective at treating hypotension in patients with septic shock. Dopamine may be particularly useful in patients with compromised systolic function but causes more tachycardia and may be more arrhythmogen ...
Heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction

... vasodilation in HFpEF compared with healthy age-matched controls.33 Symptoms of dyspnoea and fatigue in HF may be related to pathologic ergoreflex activation, which is also related to NO bioavailability.84 Intriguingly, the extent of flow-mediated vasodilation (a biomarker of endothelial function) i ...
Cardio-oesophageal reflex in humans as a mechanism for `linked
Cardio-oesophageal reflex in humans as a mechanism for `linked

... despite a small increase in blood pressure, flow through the circumflex coronary artery in the dog decreased by a quarter when a balloon was inflated in the gastrooesophageal area'181. This effect could be abolished by atropine or vagotomy. A similar reflex coronary vasoconstriction initiated in the ...
How are arrhythmias managed in the paediatric population in
How are arrhythmias managed in the paediatric population in

... vast majority of paediatric arrhythmias concerns children older than 1 year and patients with grown-up congenital heart disease. In 65% of the hospitals there is a specialized paediatric centre, and the most commonly observed arrhythmias include Wolff-Parkinson-White syndrome and atrioventricular no ...
Novel Interventional Therapies to Modulate the Autonomic Tone in
Novel Interventional Therapies to Modulate the Autonomic Tone in

... exponential growth in related health care costs. Contemporary advances in both pharmacological and nonpharmacological therapies have often been restricted in application and benefit. Given the critical role of the autonomic nervous system (ANS) in maintaining cardiovascular homeostasis in the failing ...
Parathyroid hormone level is associated with mortality and
Parathyroid hormone level is associated with mortality and

... PTH receptors are also expressed in the vessel walls and the myocardium suggesting direct effects on the cardiovascular system.1 In ...
Effect of Sublingual Nitroglycerin on Regional Flow in
Effect of Sublingual Nitroglycerin on Regional Flow in

... type of functional evaluation is not necessarily apparent from the arteriogram alone. Nitroglycerin was administered in a dose sufficient to evoke a comparable change in arterial pressure and heart rate in the patient groups studied. This approach resulted in a similar systolic arterial pressure-hea ...
reduced left ventricular systolic function differentiate between
reduced left ventricular systolic function differentiate between

... hronic heart failure is a clinical syndrome that primarily affects elderly people. The syndrome is associated with high morbidity and mortality and is often attributable to left ventricular systolic dysfunction.1 2 On the basis of previous reports, as many as 50% of patients with a reduced left vent ...
Hypertensive Heart Failure
Hypertensive Heart Failure

... hypertension and, in some cases, precedes its development (cardiogenic hypertension).20 Old age, male sex, obesity, diabetes in women, black race, and certain genetic influences such as angiotensin-converting enzyme (ACE) polymorphisms lead to a greater LVH for a given BP.21 The geometric pattern of ...
Increased alveolar/capillary membrane resistance
Increased alveolar/capillary membrane resistance

... capillary volume of blood available for physiological gas exchange. None of these changes were seen in our patient population, and in contrast, those patients with the greatest increase in alveolar/capillary membrane resistance also had increased pulmonary capillary blood volumes. A recent study of ...
Series ‘‘CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION’’
Series ‘‘CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION’’

... significant bronchopulmonary collateral blood flow, accounting for up to 30% of systemic blood flow draining directly into the pulmonary veins [29, 30]. The presence of bronchial collaterals has been used as a ‘‘biomarker’’ for the diagnosis of CTEPH [31]. A linear correlation exists between the mag ...
Influence of Right Ventricular Filling Pressure on Left Ventricular
Influence of Right Ventricular Filling Pressure on Left Ventricular

of atrial dysrhythmias - Heart
of atrial dysrhythmias - Heart

... despite the same mean quinidine blood levels, and in four the length of time of maintained sinus rhythm was unchanged. Complications to the quinidine preparation occurred in four (25%) and included undue gain in weight, skin sensitivity,gastrointestinal bleeding, and severe diarrhoea. The results of ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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