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Guidelines for the diagnosis and treatment of pulmonary hypertension
Guidelines for the diagnosis and treatment of pulmonary hypertension

... developed without any involvement of the industry. The ESC Committee for Practice Guidelines (CPG) supervises and coordinates the preparation of new Guidelines and Expert Consensus Documents produced by Task Forces, expert groups, or consensus panels. The Committee is also responsible for the endors ...
Sudden Cardiac Death Thirty Years Ago and at Present. The Role of
Sudden Cardiac Death Thirty Years Ago and at Present. The Role of

... autonomic dysbalance (disturbance). This term refers to a wide range of reflex changes in the ratio of sympathetic to vagal ventricular activation over time, occurring immediately after coronary artery occlusion at the onset of acute myocardial infarction (AMI). Another trigger of VF is autonomic di ...
Influence of sibutramine on heart rate in obese patients: systematic
Influence of sibutramine on heart rate in obese patients: systematic

... weight loss(8,10). Sibutramine blocks serotonin, dopamine, and nor adrenaline uptake and the presence of high adrenergic activity may interfere with the benefits resulting from weight loss and might increase pulse rate(11). The increase in heart rate occurs through the reduction in diastolic period, ...
EMERGENCY AND CRITICAL CARE MEDICINE®
EMERGENCY AND CRITICAL CARE MEDICINE®

... or more specifically, the right atrial and right ventricular end-diastolic pressures. Extreme elevations in CVP are seen with right-sided heart failure and pericardial effusion. Pleural effusion can also cause abnormally high CVP in the absence of suspected right-sided heart failure. Monitoring CVP ...
an account of a seven year experience with
an account of a seven year experience with

... The etiologic factors were: ischemic and / or hypertensive cardiomyopathy, idiopathic cardiomyopathy and aortic valve disease. NYHA class was III or IV in all patients. The left ventricular ejection fraction ≤ 30% was the selection criterion. All patients had sinus tachycardia. Amiodarone was applie ...
Severe Hypoglycemia in Type 2 Diabetes A Hospital
Severe Hypoglycemia in Type 2 Diabetes A Hospital

... economic impact and adverse effect on quality of life. The aim of this study was to assess the incidence of and risk factors for severe hypoglycemia among patients with type 2 diabetes. Methods We evaluated a cohort of 1195 patients with type 2 diabetes followed in the outpatient clinic of Mackay Me ...
Arginine Vasopressin Levels Are Elevated and
Arginine Vasopressin Levels Are Elevated and

... Mechanisms of Release The mechanism responsible for increased AVP levels in both types of CHF is not obvious. In fact, it is likely that multiple factors affect the release of AVP in these populations. We speculate that diminished systemic blood flow in these children may stimulate stretch receptors ...
Hydrodynamics of the human circulatory system: a review.
Hydrodynamics of the human circulatory system: a review.

... Erythrocytes in Acid-Citrate-Dextrose," Prothero and Burton provide experimental evidence of the steady passage of mammalian red cells, at low pressure, through pores of 5.0 or 3.0 microns in diameter, with no evidence of hemolysis. ...
2.01 Structures of the Circulatory System
2.01 Structures of the Circulatory System

... Someone with type A antigen has B antibodies Someone with type B antigen has A antibodies Someone with type AB antigen has no antibodies Someone with type O antigen has A and B antibodies ...
2.01 Understand the Circulatory System
2.01 Understand the Circulatory System

... Someone with type A antigen has B antibodies Someone with type B antigen has A antibodies Someone with type AB antigen has no antibodies Someone with type O antigen has A and B antibodies ...
Interrelationships of Hepatic Blood Flow
Interrelationships of Hepatic Blood Flow

... document precisely. Previous work by Holl-unger8 and Katz9 have demonstrated in rabbit and rat experiments that the chief site of metabolism of lidocaine appears to be in the liver. To our knowledge, the present study is the first to demonstrate that the liver is a major site of metabolism or remova ...
Sequential growth of fetal sheep cardiac myocytes in response to
Sequential growth of fetal sheep cardiac myocytes in response to

... blood samples were taken for determination of plasma renin activity, for plasma protein concentration, and for blood gases, pH, and hematocrit. All experiments were begun at an average of 130 ⫾ 2 days of gestation (term is 145 days). Adult sheep plasma protein was infused in the fetal circulation as ...
2.01 structures of circ. system
2.01 structures of circ. system

... Someone with type A antigen has B antibodies Someone with type B antigen has A antibodies Someone with type AB antigen has no antibodies Someone with type O antigen has A and B antibodies ...
Effect of One and Two Split Aerobic Exercise Sessions on Circadian
Effect of One and Two Split Aerobic Exercise Sessions on Circadian

... This master oscillator also generates circadian rhythmic patterns for other biological events. It is increasingly being appreciated that many diseases have a pattern associated with circadian rhythms of various biological functions of the body, more so the cardiovascular diseases. The existence of c ...
Exenatide infusion decreases atrial natriuretic peptide levels by
Exenatide infusion decreases atrial natriuretic peptide levels by

... levels were not directly associated with exenatide levels, but were related to the action of the decreased filling pressure during exenatide infusion. In our previous study, we demonstrated that exenatide infusion increased cardiac index as a result of chronotropy, without any changes in stroke volu ...
I. Summary of Product Characteristics
I. Summary of Product Characteristics

... the revocation, as applicable are set out in the Annex II. 3. The relevant sections of the summary of product characteristics and package leaflet are set out in Annex III. 4. The conditions affecting the marketing authorisations are set out in Annex IV. 5. The timetable for the implementation of the ...
Reduced Myocardial Flow in Heart Failure Patients With Preserved
Reduced Myocardial Flow in Heart Failure Patients With Preserved

... arterial stiffness, ventricular–arterial coupling, endothelial function, and chronotropic incompetence, among others.3–5 Despite these advances, HFpEF remains a clinical syndrome without effective preventive or therapeutic options, as all randomized clinical trials in the field have yielded neutral ...
OXYGEN TRANSPORT BY THE CIRCULATORY SYSTEM OF THE
OXYGEN TRANSPORT BY THE CIRCULATORY SYSTEM OF THE

... into dorsal and ventral chambers by a septum. The base of the ventricle communicates with the atria and three great arteries: the right and left systemic arches and the pulmonary artery. The ventricular septum is incomplete at the ventricular base. The right systemic arch curves dorsally and posteri ...
Cardiovascular System - Comed.uobaghdad.edu.iq
Cardiovascular System - Comed.uobaghdad.edu.iq

... 1. Sinus node "SA" node: also called sinoatrial node, located in the right atrium. It is concerned with the generation of rhythmical impulse; it is the pacemaker of the heart that initiates each heart beat. This automatic nature of the heart beat is referred to as automaticity. 2. Internodal pathway ...
Increased diastolic time fraction as beneficial adjunct of - AJP
Increased diastolic time fraction as beneficial adjunct of - AJP

... dysfunction and impaired coronary flow reserve after balloon angioplasty have been attributed to the stimulation of ␣-adrenergic pathways in the vessel wall (9, 11, 12, 16), leading to vasoconstriction not only of the manipulated coronary artery but also of a normal control vessel (9, 20). These adv ...
Atrial Fibrillation Begets Heart Failure and Vice Versa
Atrial Fibrillation Begets Heart Failure and Vice Versa

... 2012. Among 1737 individuals with new AF (mean age, 75±12 years; 48% women), more than one third (37%) had HF. Conversely, among 1166 individuals with new HF (mean age, 79±11 years; 53% women), more than half (57%) had AF. Prevalent AF was more strongly associated with incident HF with preserved eje ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... 207mg/dl (males) and 212mg/dl (females) compared to 163mg/dl (males) and 188mg/dl (females) in the diabetic patients without cardiomyopathy. Serum Triglyceride levels (165mg/dl in males and 133mg/dl in females: 98mg/dl in males and 137mg/dl in females) and serum LDL (105mg/dl in males and 98mg/dl in ...
THE FLOW OFBLOOD IN THE CORONARY ARTERIES IN
THE FLOW OFBLOOD IN THE CORONARY ARTERIES IN

... the heart, volume and output. The coronary flow was measured through the cannulae in the coronary arteries which were perfused by blood passing from a reservoir. In the top of the reservoir was placed a so-called hot wire which measured the amount of air replacing the blood flowing from it into the ...
Marcela Rosas-Nexticapa.pmd
Marcela Rosas-Nexticapa.pmd

... cardiac injury caused by ischemia/reperfusion. In this study, a new naphthalene derivative was synthetized with the objective of evaluating its activity on ischemia/reperfusion injury.The Langendorff technique was used to evaluate the effect of the naphthalene derivative on ischemia/reperfusion inju ...
Left Ventricular Remodeling in Heart Failure
Left Ventricular Remodeling in Heart Failure

... Ventricular remodeling, first described in animal models of left ventricular (LV) stress and injury, occurs progressively in untreated patients after large myocardial infarction and in those with dilated forms of cardiomyopathy. The gross pathologic changes of increased LV volume and perturbation in ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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