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The Cardiovascular System - Mediapolis Community School
The Cardiovascular System - Mediapolis Community School

... from the right atrium to the right ventricle. • The pulmonary valve allows blood to leave the right ventricle and prevents backflow into the ventricular chamber. • The mitral valve permits blood to move from the left atrium to the left ventricle. • The aortic valve allows blood to move from the left ...
Heart Rate, Blood Pressure, and Exercise
Heart Rate, Blood Pressure, and Exercise

... • Corresponds with the onset of laminar flow through the arteries • Pressure at last Korotkoff sound (a beating sound with each heart beat) • Average value is around 80 mmHg • Reflects total peripheral resistance, but is not equal to it ...
the heart - WordPress.com
the heart - WordPress.com

...  Blood pressure is typically measured along your brachial artery which can be found along the inner middle of your arm.  A normal Blood Pressure reading is typically 120/80 120 being our systolic pressure & 80 being our diastolic pressure.  Hypertension: High blood pressure ie. 140/90 or ...
Cardio GR - WordPress.com
Cardio GR - WordPress.com

... • AV Node--takes over pacemaker duties at lower rate if SA does not function – Signal leads to ventricular contraction ...
Drug Information Sheet("Kusuri-no-Shiori") Internal Published: 12
Drug Information Sheet("Kusuri-no-Shiori") Internal Published: 12

... This medicine decreases blood pressure and helps the heart function better by inhibiting the angiotensin converting enzyme (ACE) and suppressing production of angiotensin II, a substance in the body that constricts blood vessels. It is usually used to treat essential hypertension, renal hypertension ...
Nursing and heart failure
Nursing and heart failure

... - Negative chronotropic agents (betablockers, calcium channel blockers) - Reducing afterload and preload (nitrates, hydralazine, angiotensinconverting enzyme (ACE) inhibitors) - Diuretics (Thiazides, Loop Diuretics) ...
Religion on Heart Disease & Hypertension - ISH-TMC
Religion on Heart Disease & Hypertension - ISH-TMC

... • T.W. Graham et al (1978) examined the relationship between a variety of sociological factors, including religious involvement and blood pressure in 771 white community-dwelling males. • They found a consistent association between frequent church attendance and lower systolic and diastolic blood pr ...
Case Study CAD Equivalent
Case Study CAD Equivalent

... • Add HCTZ or other agent as needed Smith SC et al. Circulation 2011;124:2458-2473 ...
The Cardiac Cycle
The Cardiac Cycle

... The Cardiac Cycle Aim: To understand the Cardiac Cycle ...
Heart Failure
Heart Failure

... Treatment if NYHA II • Add angiotensin converting enzyme (ACE) inhibitor • Add beta blocker ...
Cardiac Glossary of Terms
Cardiac Glossary of Terms

... Anoxia: Literally, no oxygen. This condition most frequently occurs when the oxygen supply to a part of the body is critically diminished. This may result in the death of the affected tissue. ...
Glossary of Cardiac Terminology
Glossary of Cardiac Terminology

... Anoxia: Literally, no oxygen. This condition most frequently occurs when the oxygen supply to a part of the body is critically diminished. This may result in the death of the affected tissue. ...
What do the following values refer to?
What do the following values refer to?

... What branch of the autonomic nervous system regulates vasoconstriction of arterioles? In times of stress, why do skeletal muscles arterioles vasodilate? The blood vessels to the brain and heart never vasoconstrict - why? Kidneys can reabsorb water (into the bloodstream). What effect does this have o ...
Cardiovascular Fitness Study Guide
Cardiovascular Fitness Study Guide

... Cardiovascular Disease is the number 1 cause of death in America! -It is estimated that over ½ of these deaths could have been prevented with a change in the person’s lifestyle ...
Circulatory system
Circulatory system

... WALL- have 3 LAYERS  INNER- simple squamous epithelium + connective tissue= endothelium  Middle- smooth muscle  Outer- loose and fibrous connective tissue Arterioles- tiny arteries ...
What causes hypertension
What causes hypertension

... According to McCance and Heuther, primary (also called essential or idiopathic) hypertension, defined as “combined systolic and diastolic hypertension . . . [with] no known cause”, is the most widely diagnosed form of the disease, affecting “90% to 95% of hypertensive individuals” (McCance and Heuth ...
abstract - Platform 14
abstract - Platform 14

... Background: drug-coated balloons (DCB) have shown to be a valuable alternative to stents for the treatment of in-stent restenosis, and there is some initial evidence of their efficacy for the treatment of small coronary vessels. Newer generation DCB were developed to overcome the reduced deliverabil ...
Myocardial Infarction - Acute - Secondary Prevention
Myocardial Infarction - Acute - Secondary Prevention

... only if there are clinical side effects of the therapy. Propranolol, timolol and metoprolol have been used in the largest randomized controlled trials, but there is no evidence that the benefits are not a class effect. Patients who prove intolerant of a beta-blocker after a large infarction should b ...
Cardiovascular System: Blood Vessels and Circulation
Cardiovascular System: Blood Vessels and Circulation

Red Blood Cells
Red Blood Cells

... Hormones and Arterial B.P. • Norepinephrine/Epinephrine (adrenal medulla) – at higher levels ↑ B.P. • Arginine vasotocin and Mesotocin - increase B.P. at physiological concentrations probably via increased water retention + vasoconstrictor? • Histamine (not a hormone) from basophilsvasodilator (rel ...
Cardiovascular Systems - Seattle Central College
Cardiovascular Systems - Seattle Central College

... – Avenues of exchange: between endothelial cells, protein channels, cell membranes, major sinuses – What factors affect diffusion rates?: short _______, ...
Cardiovascular class
Cardiovascular class

... Modify the uptake and utilization of calcium in the smooth muscle cells of the blood vessel wall Caution/Side-effects: swelling in distal extremities, especially feet and ankles (dependent edema) Angiotensin converting enzyme Controls blood pressure ACE inhibits this chain at the top level and preve ...
Atrial fibrillation - The Castle Practice
Atrial fibrillation - The Castle Practice

... clots that can form in the heart. As a result, most people are advised to use a treatment to reduce the risk of developing blood clots. The most commonly used treatments include anti-coagulants (also called blood thinners) or anti-platelet drugs (such as aspirin). Anticoagulant drugs — Taking an ant ...
Yang ZH, Madinova A, Kozai T, Joch H, Aebi U, Luscher TF
Yang ZH, Madinova A, Kozai T, Joch H, Aebi U, Luscher TF

... a calcium antagonist/beta-blocker combination to have superior antihypertensive efficacy compared to each agent alone. One such study involved randomization of patients (n=159) with mild hypertension to treatment with felodipine 10 mg/day, metoprolol 100 mg/day or a combination of both for 12 weeks. ...
Body Systems and Your Health - St. John Paul II Collegiate
Body Systems and Your Health - St. John Paul II Collegiate

... It is ironic that at a time in history when we have products available year-round from every corner of the world; when there are magazines, television shows, web sites, etc. devoted to food and exotic recipes; when large numbers of people have generous disposable incomes – still the North American ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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