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Congenitally corrected transposition of great arteries with ischemic
Congenitally corrected transposition of great arteries with ischemic

... diseases, and if uncorrected, is commonly fatal in the first year of life.7 The clinical course is complicated by associated intracardiac defects such as ventricular septal defect, subvalvar and valvar pulmonary stenosis, left AV valve regurgitation, and AV conduction disturbances.8 Patients with co ...
Left ventricular filling pressure in male patients with type 2 diabetes
Left ventricular filling pressure in male patients with type 2 diabetes

... changes in the regulation of peripheral hemodynamics. LTT is highly prevalent among individuals with type 2 diabetes. The aim of this study was to compare LVF in male diabetic patients with no structural heart disease and normal serum testosterone levels vs. those with LTT. Methods: Type 2 diabetic ...
Blood Pressure
Blood Pressure

...  A heart attack, or myocardial infarction, is the damage or death of cardiac muscle tissue resulting from blockage of one or more coronary arteries  A stroke is the death of nervous tissue in the brain, usually resulting from rupture or blockage of arteries in the head  Aspirin inhibits inflamma ...
Circulatory System
Circulatory System

... blood forcing its way through the cuff ...
B-type Natriuretic Peptide (BNP) Testing
B-type Natriuretic Peptide (BNP) Testing

... BNP measurements must be assessed in conjunction with standard diagnostic tests, medical history and clinical findings. The efficacy of BNP measurement as a stand-alone test has not been established yet. BNP measurements for monitoring and management of CHF are non-covered. Treatment guided by BNP h ...
Liver transplantation in a Jehovah`s Witness with ankylosing
Liver transplantation in a Jehovah`s Witness with ankylosing

... Aprotinin has been demonstrated to decrease the risk of allogenic blood transfusion in a recent metaanalysis of prospective, randomised, controlled studies of pharmacological strategies to decrease bleeding associated with cardiac surgery.1 6 A similar analysis has not been done with patients who ha ...
Heart Failure
Heart Failure

... that ABO-incompatible heart transplantation can be 2. Beniaminovitz A, Itescu S, Lietz K, et al. Prevention of rejection performed safely in infants, thereby markedly re- in cardiac transplantation by blockade of the interleukin-2 receptor ducing mortality among children with end-stage with a monocl ...
Obesity - Pennington Biomedical Research Center
Obesity - Pennington Biomedical Research Center

... There are two forms of stroke: ischemic and hemorrhagic. Ischemic stroke occurs when an artery to the brain is blocked. Overweight and obesity increase the risk for ischemic stroke in men and women. With increasing BMI, the risk of ischemic stroke increases progressively and is doubled in those with ...
Septic Shock Pulmonary Artery Line
Septic Shock Pulmonary Artery Line

... you may ask the patient to deep breathe and cough, or reposition patient in bed to dislodge it. However, notify physician immediately to reposition catheter by pulling back gently; then, get chest x-ray to confirm proper placement. Do not attempt to flush! 4. If patient coughs up blood or it is suct ...
CFS is Heart Failure Secondary to Mitochondrial Malfunction
CFS is Heart Failure Secondary to Mitochondrial Malfunction

... cardiac output lying down, but standing up they are in borderline heart and organ failure. CFS is therefore the symptom which prevents the patient developing complete heart failure. Actually, everyone feels more rested when they are sitting down with their feet up! The subconscious has worked out th ...
OAC Panel Recommendation Slide Deck
OAC Panel Recommendation Slide Deck

... STEMI patients taking maintenance DOAC therapy who do not have access to timely primary PCI should generally receive immediate fibrinolytic therapy and usual adjunctive antithrombin therapy. STEMI patients taking maintenance VKA therapy who do not have access to timely primary PCI should have their ...
February 9, 2015 - Twin Cities Health Professionals Education
February 9, 2015 - Twin Cities Health Professionals Education

... Leaking or rupture of an aortic aneurysm is usually a lifethreatening emergency. If the wall is weakened enough, the aneurysm will rupture, resulting in aortic blood being pumped into either the chest or abdominal cavity. The patient may bleed to death (exsanguinate) in a very short time. More commo ...
Circulatory System:
Circulatory System:

... Generating blood pressure Routing blood Heart separates pulmonary and systemic circulations Ensuring one-way blood flow Regulating blood supply Changes in contraction rate and force match blood delivery to changing metabolic needs ...
1 - jemds
1 - jemds

... Lipoprotein (a) is a complex lipoprotein consisting of a central core of LDL (low density lipoprotein), covalently linked by a single disulphide bond to a polypeptide chain of apoprotein (a) Many studies have shown a direct relationship between LP (a) and CAD (3) In India, the percentage is rising w ...
Principles of Isolated Heart Perfusion
Principles of Isolated Heart Perfusion

... The isolated perfused heart system, as originated by Oscar Langendorff more than a century ago, has become a mainstay of pharmacological and physiological research. The system allows the examination of cardiac inotropic, chronotropic and vascular effects without the complications of an intact animal ...
Chapter 14 PPT
Chapter 14 PPT

... cause of death in the US. • Controllable AMI risk factors: – Cigarette smoking, high blood pressure, high cholesterol, high blood glucose level (diabetes), lack of exercise, and stress ...
Heart Failure and Cardiac Transplant
Heart Failure and Cardiac Transplant

... A recent study by Preis evaluated the percentage of intermediate risk patients among more than 3,500 participants in the Framingham Heart Study Offspring and Third Generation cohort participants who could potentially be reclassified as having high CHD risk based on the presence of a high CACS (as de ...
37–1 The Circulatory System
37–1 The Circulatory System

... The layer of muscle in the heart that pumps blood through the circulatory system is called the ...
Heart Failure: How Is It Diagnosed?
Heart Failure: How Is It Diagnosed?

... treatment. Common tests include: • Blood tests. Routine blood tests can help your doctor identify the cause of heart failure, find out if your kidneys and liver have been affected, and know whether you have risk factors, such as diabetes or high blood pressure. • Electrocardiogram (EKG or ECG). An E ...
A method for accurate localization of the  Linköping University Postprint
A method for accurate localization of the Linköping University Postprint

... Accurate localization of heart sounds in noisy phonocardiographic (PCG) signals is difficult. Several methods such as Shannon energy (Liang et al 1997), homomorphic filtering (Gupta et al 2007), frequency analysis (Iwata et al 1980), entropy (Yadollahi and Moussavi 2006) and recurrence time statisti ...
File
File

... pumping large amounts of blood each time it contracts. This also means that the fitter individual will also have a lower resting heart rate as his/her heart does not need to beat as often since each contraction of the ventricle allows so much blood to move through the body. During exercise, cardiac ...
(1-7)对腹主动脉缩窄大鼠心肌肥厚和纤维化的影响
(1-7)对腹主动脉缩窄大鼠心肌肥厚和纤维化的影响

... progression of ventricular hypertrophy. Drugs like ACE inhibitors (ACEIs) and angiotensin AT1 receptor blockers (ARBs) are able to reverse the progression of ventricular hypertrophy in patients with hypertension and reduce the infarct size in animal models of myocardial ischemia-reperfusion injury[4 ...
An approach to the diagnosis and management of valvular heart
An approach to the diagnosis and management of valvular heart

... Clinical features and special investigation findings are described in Table 1.[2] Patients with mild disease and symptoms may require diuretic therapy and sodium restriction to reduce congestion. Beta-blockers are often prescribed, the rationale being that reducing the heart rate increases diastolic ...
Clinical aspects of hypertensive myocardial fibrosis
Clinical aspects of hypertensive myocardial fibrosis

... have symptoms and signs of myocardial ischemia despite angiographically normal coronary arteries, and this was found to be related to impaired coronary flow reserve [27]. The impairment of coronary vasodilator reserve is likely to initiate a process of myocardial malperfusion and malnutrition, which ...
Titration of Beta Blockers
Titration of Beta Blockers

... *If severe HF max dose 25mg bd. If mild to mod HF max dose 50mg bd if weight >85kg otherwise max dose 25mg bd How to use: • Ensure patient has stable mild to moderate HF (NYHA Class 1-3) • Start with low dose & double dose at not less than 2 weekly intervals • Aim for target dose or highest tolerate ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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