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The Arterial and Venous Systems - Dr. Pittman
The Arterial and Venous Systems - Dr. Pittman

... need to remember that the factors which can change pulse pressure are stroke volume of the left ventricle, compliance of the large arteries and total peripheral resistance. Thus, response 2 is correct. If heart rate increases and stroke volume is constant, then cardiac output must also increase, so ...
Heart rate and atherosclerosis Jean-Claude Tardif *
Heart rate and atherosclerosis Jean-Claude Tardif *

... HR acceleration was 8.7%, whereas at rates in excess of 90 b.p.m., the likelihood increased to 18.5%.25 In addition, HR can also directly influence the underlying atherosclerotic process as described below. ...
Surrogate Measures of Arterial Stiffness
Surrogate Measures of Arterial Stiffness

... contrast to what was discussed above, AASI remained significantly correlated to peripheral and central systolic augmentation after adjustment on confounding factors.7 Pathophysiological conditions and drugs can change PP and augmentation index without changing aortic PWV, suggesting a predominant ef ...
Twelve-lead
Twelve-lead

... Infarction (Acute)—abnormal Q wave, ST segment may be elevated and T wave may be inverted Infarction (Age Unknown)—abnormal Q wave, ST segment and T wave returned to normal ...
Heart Failure
Heart Failure

... Americans have multiple chronic conditions; this figure rises to 75% in those >65 years of age, including the diseases referred to above, as well as asthma, hypertension, cognitive disorders, or depression. Most random controlled trials (RCTs) in HF specifically excluded patients with significant ot ...
PDF - Bentham Open
PDF - Bentham Open

... Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece; 2First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece; 3Thir ...
Blood / Cardiovascular System
Blood / Cardiovascular System

... 10. Scoring is by time with each error adding 15 seconds to the team time. Additional Rules 1. Other players are not allowed to communicate with the player who is at the Sticky Cloth searching for and putting up a sheet. The team is penalized one point (or 15 seconds) for violating this rule. 2. Pl ...
the challenge of prescribing statins for primary prevention in the
the challenge of prescribing statins for primary prevention in the

... Source: Savarese G, Gotto AM, Paolillo S et al. Benefits of statins in elderly subjects without established cardiovascular disease: a meta-analysis. J Am Coll Cardiol 2013;62(22):2090-9.4 Statin safety concerns in the elderly In the Heart Protection study (HPS),18 which compared simvastatin 40 mg to ...
the giant heart - The Franklin Institute
the giant heart - The Franklin Institute

... The Giant Heart exhibit invites learners to learn about the structure of the human heart and how it functions as the pump for the circulatory system. In many ways, the human heart is a very simple four-chambered organ. However, the role it plays in human life is extraordinary. The exhibit showcases ...
Sunshine Heart Implants First Patient in C
Sunshine Heart Implants First Patient in C

... additional long-term benefit of having patients discontinue use of the device due to sustained improvement in their condition as a result of the therapy. This occurred in some feasibility study patients. The C-Pulse system is implanted without any incisions into the heart itself or to any major vess ...
8  Conclusions & future directions
8 Conclusions & future directions

... result of hypertrophy alone is a good sign, while RV diastolic stiffening due to intrinsic RV wall changes, such as fibrosis or sarcomeric stiffening, is not a beneficial sign and occurs mainly in patients who are transitioning from adaptative remodeling to RV failure. Therefore, it could be of grea ...
ventricular tachycardia
ventricular tachycardia

... If normal EF and apparently structurally normal heart • Consider ICD and/or pharmacological therapy if etiology of SCD is understood • Examples: • ARVD • Brugada syndrome: consider ICD therapy given high risk of SCD • Long QT syndrome ...
HYPERTENSION AND ARRHYTHMIA
HYPERTENSION AND ARRHYTHMIA

... Myocardial ischemia: Myocardial ischemia is the most common arrhythmogenic factor, and this is also true in hypertensive subjects. This comorbidity increases the risk of sudden death. The ischemia may be secondary to atherosclerosis of the major epicardial coronary arteries, or due to problems in th ...
Heartbeat: Is biologic age best defined by exercise capacity?
Heartbeat: Is biologic age best defined by exercise capacity?

Vascular impedance
Vascular impedance

... • The pulse frequency of the human cardiovascular system, f, is the frequency of the systolic wave, 1/[2 tpp] in which tpp is the time interval from (dP/dt)max to (dP/dt)min. The peak-to-peak amplitude [dP/dtMax - dP/dtMin] was defined as (dP/dt)pp, and obtained from the systolic ...
The systemic circulation Blood flow Control of the systemic circulation
The systemic circulation Blood flow Control of the systemic circulation

... Cardiovascular responses to anaesthesia All anaesthetic agents have a direct depressant effect on the myocardium. Therefore they reduce myocardial contractility, and many also reduce sympathetic stimulation of the vascular system. The result is a decreased cardiac output accompanied by vasodilation, ...
Physiology of the Mesenteric Circulation
Physiology of the Mesenteric Circulation

... moment in time (4). The structure regulating blood flow through the individual capillary is a smooth muscle thickening around the origin of the microvessel. This thickening has been termed the “precapillary sphincter.” When this sphincter contracts it closes off the capillary to the flow of blood an ...
Brief Review - Hypertension
Brief Review - Hypertension

... by arterial pressure. Mitchell et al3,63 argue that “effective aortic diameter” measured indirectly using the water hammer equation is reduced in persons with isolated systolic hypertension. Such a view gains some support from Framingham data,24 which showed, after correction for age, that there is ...
File - Caitlin Baker
File - Caitlin Baker

... CAD participants and from 109 mg/dL to 104 mg/dL in high risk patients. The initial BMI in CAD patients was 32.3 which dropped to 30.2 within three months while the average initial BMI of high risk patients went from 34.2 to 32.9. The blood pressures went from an average of 127/76 to 115/70 in three ...
January 2017 - Maryland Poison Center
January 2017 - Maryland Poison Center

... complaining of intense pain, especially at the tips of his fingers. There are no visible burns or discoloration on his hands. Hydrofluoric acid (HF) is a weak acid that is used in many industries for metal cleaning, glass etching and electronics manufacturing. It is also found in households in rust ...
utmj submission template - University of Toronto Medical Journal
utmj submission template - University of Toronto Medical Journal

... vitamin K which normally increases production of various clotting factors in the body.15 Heparin’s pharmacology is less well described but its anticoagulant properties are thought to originate with heparin’s ability to inhibit the enzyme anti-thrombin which inactivates the protein thrombin. Various ...
June 2007
June 2007

... Both systems are connected by the perforatical veins. A mechanism that supports the backflow in the veins is referred to as the “muscle pump.” When moving leg muscles the blood in the nearby veins is prevented from flowing back by the anatomical proximity of muscles and veins. In patients with varic ...
Prognostic value of TAPSE after therapy optimisation in patients with
Prognostic value of TAPSE after therapy optimisation in patients with

... What does this study add? ▸ The study shows that a readily available measure of right ventricular function obtained at echocardiography has a prognostic role in the follow-up of patients with pulmonary arterial hypertension, similar to what has been demonstrated with more complex imaging techniques. ...
Bio112-2015_Assessment_Content-Objective1
Bio112-2015_Assessment_Content-Objective1

... 43. Which of the following mechanisms would prevent transfer of information between two neurons (synaptic transmission) with a chemical synapse? 0.803% Correct (D) a. inhibition of voltage-gated calcium channels in the pre-synaptic membrane b. inhibition of neurotransmitter binding to ligand-gated ...
When arrhythmias complicate heart failure - Af
When arrhythmias complicate heart failure - Af

... inferior to the atrial fibrillation one. In most cases, arrhythmias (both atrial and ventricular) occur due to the same underlying heart disease, but in other circumstances they can be only adverse effects of drugs we use to treat this syndrome. I am referring to positive inotropic drugs like catech ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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