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Management of Common Arrhythmias: Part II. Ventricular
Management of Common Arrhythmias: Part II. Ventricular

... complexes without sustained ventricular tachycardia is more an annoyance than a medical risk, and treatment is not required. In contrast, patients with established heart disease and premature ventricular complexes have a higher likelihood of developing ventricular tachycardia or fibrillation. These ...
Heart Failure - Tower Hamlets
Heart Failure - Tower Hamlets

... This factsheet describes Heart Failure, a complex clinical syndrome based around the premise that the ability  of the heart to act as a pump is impaired.  It is an important condition as it is a consequence of coronary heart  disease (CHD), the prevalence of which is increasing rapidly in the UK des ...
Relation of Ankle Brachial Index to Left Ventricular
Relation of Ankle Brachial Index to Left Ventricular

... correlated inversely with LVEF in the patients with (r =0.52, p=0.008) and without (r=-0.55, p<0.001) IHD. Regression analysis showed that both age [OR=1.14, CI (1.03-1.27), p=0.01] and LVEF [OR=0.06, CI (0.0080.50), p=0.009] were related to ABI. Discussion The ankle-brachial index has been used as ...
Cardio-Respiratory Exercise Physiology
Cardio-Respiratory Exercise Physiology

... 2014. Snowboarders travel down a slope dotted with obstacles, including quarterpipes, rails and progressively higher jumps. On the way, they perform feats of aerial acrobatics, with tricks like the backside triple cork 1440 — three head-over-heels flips and four full revolutions. ...
Electric Currents Applied During the Refractory Period Can
Electric Currents Applied During the Refractory Period Can

... Introduction Current therapies for heart failure, including diuretics, digoxin [1], angiotensin converting enzyme inhibitors [2], spironolactone [3] and beta-blockers [4,5] have signi®cantly improved patient survival and quality of life. However, both mortality and morbidity remain high in this cond ...
pumping life - Discovery Education
pumping life - Discovery Education

... The program examines the three major types of vessels that make up the circulatory system — arteries, veins, and capillaries. Students could learn that arteries carry blood away from the heart, and they see how the thick elastic walls of arteries expand and contract as the heart pumps blood through ...
Cardiovascular examination
Cardiovascular examination

... mesuring the BP in supine position and then at aleast 1 min before mesuring it again after standing . If pt cant stand you may ask him to dangle his feet for a while. With standing blood pools into the lower limbs and reduces the venous return and the cardiac output.. This leads to increase epinephr ...
Ch. 20-Drugs Used to Treat Dysrhythmias
Ch. 20-Drugs Used to Treat Dysrhythmias

PDF
PDF

... recurrent stroke prevention.5,6 When the hypothesis was carefully tested in the main phase National Institute of Neurological Disorders and Stroke/National Institutes of Health (NINDS/NIH)-funded clinical trial, this did not turn out to be the case because we found no significant difference between ...
preview as pdf - Pearson Higher Education
preview as pdf - Pearson Higher Education

... The contraction and relaxation of the heart constitute one heartbeat and this process is called the cardiac cycle (Figure 29–6 •). Ventricular filling is followed by ventricular systole, a phase during which the ventricles contract and eject blood into the pulmonary and systemic circuits. Systole is ...
Articles Mortality risk among sulfonylureas: a systematic review and
Articles Mortality risk among sulfonylureas: a systematic review and

... safety, sulfonylureas remain the most commonly used second-line oral antidiabetic drugs in patients with type 2 diabetes when metformin monotherapy does not successfully control blood glucose or is contraindicated.30–33 Regardless of the mechanism, assessment of whether the risk of adverse cardiovas ...
Left Ventricular Pressure-Volume and Frank-Starling
Left Ventricular Pressure-Volume and Frank-Starling

... nonathletes. Second, they also had a greater change in stroke volume with any change in central blood volume and cardiac filling pressure, as manifested by the slope of the steep linear portion of these curves. This slope, determined over a range of filling pressures from 1 to 13 mm Hg by linear reg ...
PLoS ONE
PLoS ONE

... (20.7%) in the cAC group, and 131 (79.3%) to the minimally/unaffected control group, with falls in LVEF of 7.7±0.4% (p<0.0001) and 0.6±0.3% (p = 0.02) respectively. No subjects developed overt anthracycline cardiotoxicity. No focal fibrosis was identified using late gadolinium enhancement (imaged in ...
Myxomatous valve degeneration: A look at the latest developments
Myxomatous valve degeneration: A look at the latest developments

HbA1c: A Marker for Severity of Acute Myocardial Infarction
HbA1c: A Marker for Severity of Acute Myocardial Infarction

... tests. P-value of less than 0.05 was taken as level of significance Results: Poor glycemic control was seen in 52.5% patients. No difference was observed between the groups with respect to gender distribution, duration of hospital stay and patient’s outcome. Past history of MI was found to be signif ...
About Peripheral Artery Disease
About Peripheral Artery Disease

... everyone has this symptom. Women are more likely to have heartburn, a hard time catching their breath, pain or pressure between the shoulder blades or extreme tiredness. Older people and people with diabetes are more likely to be short of breath, very tired or light-headed. ...
Quantitative comparison of canine right and left ventricular
Quantitative comparison of canine right and left ventricular

... in our data analysis. This 50% point for alignment of the pressure waves appears to us to be the most sensitive and reliable in comparison to other points in the cardiac cycle such as end diastole or time of peak pressure. The definition of end diastole is vague; any definitions based on the charact ...
Population prevalence, incidence, and predictors of
Population prevalence, incidence, and predictors of

... questionnaire was used to determine the presence of angina pectoris (classified as none, possible or definite).9 Evidence of chronic bronchitis was assessed using the Medical Research Council’s bronchitis questionnaire.10 Subjects were also asked about their medical history and current status. This ...
Teacher`s Resource Guide - American Heart Association
Teacher`s Resource Guide - American Heart Association

... • Children who are overweight from the ages of seven to 13 may develop heart disease as early as age 25. • Children in their early teens who are obese have arteries similar to 45-year-olds. • Obesity takes a physical toll and also often causes children to suffer from low self-esteem, negative bo ...
Sympathetic neural hyperactivity and its
Sympathetic neural hyperactivity and its

... hyperactivity has been investigated only after AMI. We aimed to quantify central sympathetic output to the periphery in patients with UA, investigate its progress over time relative to that after uncomplicated AMI and to explore the mechanisms involved. Muscle sympathetic nerve activity (MSNA) asses ...
Lecture 3 + 4 - Cardiac Cycle (2012).
Lecture 3 + 4 - Cardiac Cycle (2012).

... at this stage the pressure in the ventricles is slightly above 02mm Hg. As the intra-ventricular pressure rises, it pushes the cusps of the A-V valve up and the A-V orifices are closed. The pressure in the ventricular cavities continues to rise but remains less than that in the large arteries. Thus, ...
Exercise physiology introduction
Exercise physiology introduction

... Services may be provided in several medical settings such as: hospitals, rehabilitation centers, and outpatient clinics.nd delay the onset of chronic disease in healthy participants or provide therapeutic or functional benefits to patients with underlying ...
1 A case report on Ebstein anomaly
1 A case report on Ebstein anomaly

... Ebstein's anomaly is a rare heart defect that's present at birth (congenital). In Ebstein's anomaly, your tricuspid valve — the valve between the two right hearts chambers (right atrium and right ventricle) — doesn't work properly. The tricuspid valve sits lower than normal in the right ventricle, a ...
Pathology N.47 Diseases of the heart part 1
Pathology N.47 Diseases of the heart part 1

... conversion of a stable atherosclerotic plaque to unstable one, usually with superimposed thrombosis. The conversion involves the following changes 1- Erosion, ulceration, fissuring or rupture; these are complicated by superimposed thrombosis. 2- Hemorrhage into the plaque, expanding its volume and t ...
OCR GCSE (9-1) Physical Education
OCR GCSE (9-1) Physical Education

... travels around the body in one complete circuit. Teacher instructions and answer sheet accompany two choices of activity: • Simple Un-Jumble (Learner Resource 2): the order of the structures is jumbled. A description is attached to each structure. • Doubly-Difficult Un-Jumble (Learner Resource 3): ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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