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Read more (Word document) - Ontario Lung Association
Read more (Word document) - Ontario Lung Association

... Toronto have shown that the surgery can safely be done with reproducible results in all centers (14). The overall operative mortality after elective pulmonary endarterectomy is 2% in our experience in Toronto with 74% of the patients being extubated within 2 days after surgery and 65% discharged ho ...
Giant right ventricular outflow tract thrombus in hereditary
Giant right ventricular outflow tract thrombus in hereditary

... severe infections [12]. More recently, partial splenectomy is emerging as a possible treatment option to overcome these complications, although long-term data on infection and vascular risk are still lacking [13]. The impact of splenectomy on the increased thromboembolic risk was demonstrated in a p ...
View PDF
View PDF

... B. true 6. The heart can't change how fast it pumps. A. true B. false ...
Management of Common Arrhythmias
Management of Common Arrhythmias

... of class IA agents and their detrimental effects on left ventricular function, these drugs are now used less often than amiodarone for primary therapy of atrial fibrillation.4 Amiodarone therapy is successful in 86 percent of patients who have had atrial fibrillation for less than two years.4,9 Trea ...
Obesity and the Risk of Heart Failure
Obesity and the Risk of Heart Failure

... alcohol consumption, and valve disease, the hazard ratios for heart failure per increase of 1 in the bodymass index were 1.08 (95 percent confidence interval, 1.06 to 1.11) in women and 1.07 (95 percent confidence interval, 1.04 to 1.11) in men. In these models, in comparison with subjects with a no ...
Chapter 19, Cardiovascular System
Chapter 19, Cardiovascular System

...  Blood pressure cycles over a 24-hour period  BP peaks in the morning due to waxing and waning levels of retinoic acid  Extrinsic factors such as age, sex, weight, race, mood, posture, socioeconomic status, and physical activity may also cause BP to vary ...


... tasks were chosen that better mimic daily situations (Ewart & Kolodner, 1993). Thoug-h fruir Tl il principle, a limitation of ihis approach is that it is hardly feasible to simulate in the labo_ ratory the entire variety of stressful situations encountered in real-life. We think that, in fact, the c ...
Peripartum cardiomyopathy- a pregnancy related disorder
Peripartum cardiomyopathy- a pregnancy related disorder

... preexisting hypertension and preeclampsia . Preeclampsia is commonly seen in pregnancy, symptoms like high blood pressure, protein in the urine,swelling,sudden weight gain, headaches and blurred vision that occur after the 20th week of gestation. Some reports exist about a latent form of cardiomyopa ...
PHYSIOLOGICAL RESPONSES TO EXERCISE
PHYSIOLOGICAL RESPONSES TO EXERCISE

... soon as you begin to exercise your muscle cells increase their demands for oxygen (O2). As exercise continues there is also an increased need to remove wastes such as carbon dioxide(CO2) and lactic acid. Immediately, your heart will beat faster and your breathing rate will increase to try and meet ...
15_lect modified
15_lect modified

... Classes of Antihypertensive Drugs • Aldosterone receptor antagonists (blockers) • Angiotensin II antagonists • Angiotensin-converting enzyme inhibitors • -Blockers – 1-Selective – Nonselective • -Blockers ...
Narrow Complex Tachycardias - Calgary Emergency Medicine
Narrow Complex Tachycardias - Calgary Emergency Medicine

... 78 yo F presents w/ NCT Hx of PSVT – ECG looks identical Had severe side effects w/ adenosine previously & refuses repeat Does not want to be shocked either When you ask for Verapamil the nurse points out her pressure is only 88/65 What can you do? ...
Tissue Oxygenation Monitoring as a Guide for Trauma
Tissue Oxygenation Monitoring as a Guide for Trauma

... Hypoperfusion is the most common event preceding the onset of multiple organ dysfunction syndrome during trauma resuscitation. Detecting subtle changes in perfusion is crucial to ensure adequate tissue oxygenation and perfusion. Traditional methods of detecting physiological changes include measurem ...
Atrial fibrillation - Heart Rhythm Alliance
Atrial fibrillation - Heart Rhythm Alliance

... Many factors can influence the best therapy for your individual case. The good news for people with atrial fibrillation is that there are a greater range of treatments and more effective treatments than ever before. ...
Mortality in patients with TIMI 3 flow after PCI in relation to time delay
Mortality in patients with TIMI 3 flow after PCI in relation to time delay

... Background. Percutaneous coronary intervention (PCI) performed within 12 h from symptom onset enables complete blood flow restoration in infarct-related artery in 90% of patients. Nevertheless, even with complete restoration of epicardial blood flow in culprit vessel (postprocedural Thrombolysis in ...
MYOCARDITIS
MYOCARDITIS

... • Anticoagulation is recommend in patients who fulfill the following criteria: – Symptomatic heart failure with a LVEF below 20 ...
EC2021-Medical Electronics Lesson Notes
EC2021-Medical Electronics Lesson Notes

... 4. In a research laboratory, scientists want to record from single cells in a culture dish. They want to record action potentials from single, isolated heart cells. What kind of electrode would they need to use (describe material and design)? Give a simplified schematic (circuit model of the electro ...
Hemodynamics and Ventricular Function in the Day-12 Rat
Hemodynamics and Ventricular Function in the Day-12 Rat

... In seven embryos, cardiac image was recorded by a highspeed video system (HSV-400, NAC, Tokyo, Japan) with a speed of 200 framesls. From the images, a ventricular outer (epicardial) border was manually traced and its area was obtained by a computer-assisted planimetry for each frame to construct a t ...
Ventricular Septal Defects
Ventricular Septal Defects

... • Cardiac catheterization (rarely needed, unless there are concerns of high blood pressure in the lungs) ...
The Frank-Starling Curve
The Frank-Starling Curve

... work of this beat (ABC) is given by the area within the loop |. As left ventricular pressure increases, stroke work rises and then falls even though the contractile strength is constant as judged by isovolumic pressure development. Therefore left ventricular pressure must be kept artificially cons­ ...
Full Text  - Res Cardiovasc Med
Full Text - Res Cardiovasc Med

... focus on these two medications (Table 2-4). The preference of one of these new oral anticoagulants over Warfarin is less clear among patients who already receiving Warfarin and have stable anticoagulation (time in therapeutic range > 65%) and no bleeding complications. In addition we have to keep in ...
Pulmonary Hypertension in Transgenic Mice Expressing a Dominant
Pulmonary Hypertension in Transgenic Mice Expressing a Dominant

... tet-BMPRIIdelx4⫹ mice developed pulmonary hypertension by 8 weeks of age. Like other type II receptors in the TGF␤ superfamily, signaling function of BMPRII requires binding to ligand, dimerization with, and phosphorylation of a type I receptor and, finally, phosphorylation and activation of a signa ...
Atrial Fibrillation in the Heart Failure Population
Atrial Fibrillation in the Heart Failure Population

... amiodarone. Digoxin slows atrioventricular (AV) conduction mostly at rest, but is ineffective during periods of sympathetic stimulation and therefore is not effective during exercise. Beta blockers slow AV conduction both at rest and with exercise and therefore are preferred for this reason as well ...
AHA/ACC Guideline
AHA/ACC Guideline

... cardiovascular or coronary event. For hospitalized patients, initiate lipid-lowering medication as recommended below before discharge according to the following schedule: • LDL-C should be ⬍100 mg/dL I (A), and • Further reduction of LDL-C to ⬍70 mg/dL is reasonable. IIa (A) • If baseline LDL-C is ⱖ ...
Atrial Fibrillation
Atrial Fibrillation

... Unless conversion to a normal rhythm is needed immediately, doctors recommend that most people take an anticoagulant for 4 weeks before cardioversion of established atrial fibrillation or flutter is attempted.  But, sometimes there is a specific reason not to use an anticoagulant. People who have u ...
Tachyarrhythmias, Diagnosis and Management
Tachyarrhythmias, Diagnosis and Management

... decompensated congestive heart failure to slow ventricular response. • Digoxin alone is rarely effective when the patient is sympathetically driven • Avoid high dose digoxin with amiodarone as digoxin levels increase 2-fold with amiodarone ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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