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Relation between Doppler transmitral flow and wall motion
Relation between Doppler transmitral flow and wall motion

... we sought to evaluate whether changes in Doppler transmitral flow profile are related to the severity and extent of dipyridamole-induced wall motion abnormalities in patients with coronary artery disease. Thirty-five patients (mean age 61.3 ± 12 years, 21 men) with known coronary artery disease (³ 7 ...
Avandia - GSK Source
Avandia - GSK Source

... patients with long-standing diabetes (median duration of 12 years) and a high prevalence of preexisting medical conditions, including peripheral neuropathy, retinopathy, ischemic heart disease, vascular disease, and congestive heart failure. The total number of patients with emergent congestive hear ...
Clinical Relevance of the Bezold–Jarisch Reflex
Clinical Relevance of the Bezold–Jarisch Reflex

... during increases in arterial pressure, resulting in an inhibition of vasoconstriction and peripheral vasodilation. Another systemic reflex is the BJR. The cardiac receptors mediating the BJR have very low basal firing rates in the absence of any stimulation,13,27,28 and output from these cardiac rec ...
The burden of acute coronary syndromes in the United Kingdom
The burden of acute coronary syndromes in the United Kingdom

... event, physicians recommend that patients participate in cardiac rehabilitation, adhere to a medication regime and undergo regular monitoring to prevent further life threatening events. ...
Cardiac output (CO) and systemic vascular resistance (SVR)– the
Cardiac output (CO) and systemic vascular resistance (SVR)– the

... Conditions decreasing CO directly: • Heart failure or cardiogenic shock (MI, tamponade, cardiomyopathy, bradyarrythmia) • SVR increases in compensation for decreased CO in attempt to maintain BP. ...
Heart Rate Turbulence in Patients after Percutaneous Coronary
Heart Rate Turbulence in Patients after Percutaneous Coronary

... analyses were performed using the SPSS system version 12. p value < 0.05 was considered as statistically significant. RESULTS Of the 20 eligible patients who underwent revascularization only 13 patient met our study criteria. Five patients ...
Lecture07 RADIOLOGICAL EXAMINATION OF THE
Lecture07 RADIOLOGICAL EXAMINATION OF THE

... only have mild cardiac enlargement with an otherwise normal contour. A marked increase or decrease in the transverse cardiac diameter within a week or two, particularly if no pulmonary oedema occurs, is virtually diagnostic of the condition. Pericardial effusion should also be considered when the he ...
Acute myocardial infarction in a child with myocardial bridge
Acute myocardial infarction in a child with myocardial bridge

... segment elevated 0.3-0.6 mV in the II, III, aVF, V2V6 leads. Combined with upright T, ST segment wave formed a single curve, and Q wave appeared after the disappearance of the curve. This was in accordance with the Towbin diagnosis.[14] Cardiac troponin-I, which appears in the blood at 4-6 hours aft ...
Favorable Outcomes of LVAD as Bridge to
Favorable Outcomes of LVAD as Bridge to

... filtration rate (eGFR) is a strong and independent risk factor for both incident cardiovascular disease and subsequent cardiovascular morbidity and mortality.1-3 Among heart failure patients, lower eGFR is associated with worsening functional capacity4,5 and nearly double the risk of 12-month hospit ...
Vagal Stimulation, Through its Nicotinic Action, Limits Infarct Size
Vagal Stimulation, Through its Nicotinic Action, Limits Infarct Size

... Abstract: Vagal activity has protective effects in ischemic heart disease. We tested whether vagal stimulation (VS) could modulate the inflammatory reaction, a major determinant of cardiac injury after ischemia/reperfusion. Four groups of male rats underwent myocardial ischemia (30 minutes) and repe ...
Swan-Ganz RN ICU
Swan-Ganz RN ICU

... When the inotropic state is augmented, more SW is produced at the same EDV. ...
Heart Failure: Discrepancy Between NYHA Functional Classification
Heart Failure: Discrepancy Between NYHA Functional Classification

... serum level of NT-proBNP is affected by age, gender, body mass index, renal function, and pulmonary capacity (11). Most patients who involved in this study had history and presented with components of metabolic syndrome e.g. high blood pressure, diabetes mellitus and obesity which may altered the se ...
Coronary Artery Pressure and Strength of Right Ventricular
Coronary Artery Pressure and Strength of Right Ventricular

Quality of Care for Atrial Fibrillation Among Patients
Quality of Care for Atrial Fibrillation Among Patients

... from another institution. Among the patients with AF on admission, 23.9% (n ⫽ 3,172 of 13,269) had an HR ⬎100 beats/min and 8.8% (n ⫽ 1,163 of 13,269) had an HR ⬎120 beats/min, consistent with a rapid ventricular response. The median (IQR) LVEF of patients with an admission HR ⬎120 beats/min was 40% ...
Search for HRV‐parameters that detect a sympathetic - UvA-DARE
Search for HRV‐parameters that detect a sympathetic - UvA-DARE

... attention in biomedical literature. It has been fairly well established that chronic heart failure  patients (CHF) have different heart rate variability patterns compared to matched healthy  controls (10, 35). However, many of those patients will be on ß‐blocker therapy, which has a  strong influenc ...
Left Bundle Branch Block and Left Ventricular
Left Bundle Branch Block and Left Ventricular

... for LVH in these patients with LBBB regardless of whether left ventricular thickness or cardiomegaly was used as the criterion for LVH. Both false positive and false negative errors occurred but the latter were much more common. This contrasmith the study of Pantridgee who suggested that there was a ...
Self-Powered, One-Stop, and Multifunctional
Self-Powered, One-Stop, and Multifunctional

... continuous monitoring of multiple physiological and pathological signs. As demonstrated in human-scale animals, the device can monitor heart rates, reaching an accuracy of ∼99%. Cardiac arrhythmias such as atrial fibrillation and ventricular premature contraction can be detected in real-time. Further ...
Left Bundle Branch Block and Left Ventricular Hypertrophy
Left Bundle Branch Block and Left Ventricular Hypertrophy

... for LVH in these patients with LBBB regardless of whether left ventricular thickness or cardiomegaly was used as the criterion for LVH. Both false positive and false negative errors occurred but the latter were much more common. This contrasmith the study of Pantridgee who suggested that there was a ...
reading here
reading here

... mass assay. As with troponin, an increased CKMB mass value is defined as a measurement above the 99th percentile URL using gender appropriate normal ranges [6]. However, given its greater sensitivity and specificity, troponin is definitely the preferred biomarker for the diagnosis of MI. Both cTn I ...
Impairment of left ventricular function by acute cardiac lymphatic
Impairment of left ventricular function by acute cardiac lymphatic

... West IOth Avenue, Columbus, OH 43210, USA. Tel, + 1614 293-4558; Fax + 1614293-4726. ...
Ventricular Septal Rupture After Acute Myocardial Infarction
Ventricular Septal Rupture After Acute Myocardial Infarction

... VSR is a rare but serious complication of acute myocardial infarction that is, in almost all cases, fatal without early surgical intervention. It had an incidence of 1-3% in the era before reperfusion therapy, decreasing with the introduction of thrombolytic therapy.1,2 VSR is more infrequent than a ...
Cardioversion of acute atrial fibrillation in the emergency department
Cardioversion of acute atrial fibrillation in the emergency department

... underlying structural heart disease and other etiological conditions (Table 1), alleviate symptoms, improve functional capacity and quality of life and reduce morbidity/mortality associated with AF/AFL by preventing tachycardia-induced cardiomyopathy, stroke or thromboembolism and ED visits and hosp ...
Mechanisms of Blood Flow During Cardiopulmonary
Mechanisms of Blood Flow During Cardiopulmonary

Giant right ventricular outflow tract thrombus in hereditary
Giant right ventricular outflow tract thrombus in hereditary

... severe infections [12]. More recently, partial splenectomy is emerging as a possible treatment option to overcome these complications, although long-term data on infection and vascular risk are still lacking [13]. The impact of splenectomy on the increased thromboembolic risk was demonstrated in a p ...
- Keele Research Repository
- Keele Research Repository

... Future prospective studies are needed to confirm the relationships reported, ...
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Antihypertensive drug



Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. There are many classes of antihypertensives, which lower blood pressure by different means. Among the most important and most widely used drugs are thiazide diuretics, calcium channel blockers, ACE inhibitors, angiotensin II receptor antagonists (ARBs), and beta blockers.Which type of medication to use initially for hypertension has been the subject of several large studies and resulting national guidelines. The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. The several classes of antihypertensives differ in side effect profiles, ability to prevent endpoints, and cost. The choice of more expensive agents, where cheaper ones would be equally effective, may have negative impacts on national healthcare budgets. As of 2009, the best available evidence favors the thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of view), an ACE inhibitor is recommended by NICE in the UK for those under 55 years old.
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