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Structure of the Genome
Structure of the Genome

... Chromosome packing at the molecular level. So how does the DNA fit? The DNA is wound around a series of very basic (positive) proteins called histones. These proteins are small with lots of lysine and arginine residues, giving them a high pI (~12) and lots of positive charges at pH 7. There are 5 se ...
Molecular Genetics
Molecular Genetics

... A condensed X chromosome in females. (Both males and females only need one active X chromosome.) The structure formed by the pair of homologous chromosomes during crossing over. Also called a tetrad because it consists of four chromatids. See Chromosome mutations. The attachment point on the chromos ...
3.1 Teacher Notes
3.1 Teacher Notes

... III. Genes and Gene Expression a. Genes are molecular units of heredity in all living organisms! b. Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. i. These are often proteins ...
Lecture Three: Genes and Inheritance
Lecture Three: Genes and Inheritance

... The DNA Code: Every three “letters” on the DNA represents one amino acid. In the DNA double helix, A always binds to T and G always binds to C. PROBLEM: DNA is permanently stuck inside the nucleus. The ribosomes are outside the nucleus in the cytoplasm. How does the ribosome get the code? We need a ...
Activity 10
Activity 10

... the context for this activity or the instructor can develop their own scenario. Students are asked to develop their hypothesis for the crime (Activity #7, Option A, Crime Scenario and Hypothesis Worksheet could be used for this portion of the activity). Paper, double-stranded DNA samples for the ind ...
江 苏 大 学 试 题 (A)卷
江 苏 大 学 试 题 (A)卷

... 4.3 Epigenetics focuses on uncovering the mechanism of the genetic information which is not stocked in DNA sequences but can transfer to offspring or sister cell, please describe the patterns through which organism sets up epigenetic codes (epigenetic information). 4.4 To describe the characters of ...
BOOSTER PCR FOR LOW-COPY NUMBER SAMPLES
BOOSTER PCR FOR LOW-COPY NUMBER SAMPLES

N N N N N N H purine pyrimdine Chapter 3 Nucleotides and Nucleic
N N N N N N H purine pyrimdine Chapter 3 Nucleotides and Nucleic

... Note: Identifying a particular piece of desired DNA out of the entire genome of the organism can be like finding a needle in a haystack, or worse. Typically, it is easier in practice to fragment the entire genomic DNA by partial restriction digestion (to yield entire genes rather than gene fragments ...
Understanding the ABC of DNA technology
Understanding the ABC of DNA technology

... To access the DNA inside, these cells need to be broken open, in this case by using the chemical scissors of an enzyme in buffer solution. The buffer contains an agent to stabilise the pH, a detergent to dissolve fats and to disrupt proteins in the cell. Kick start the cell disruption by using a pip ...
Bacteria Notes File
Bacteria Notes File

File - Mrs. LeCompte
File - Mrs. LeCompte

... 2) Cloning Vector = a DNA molecule that can carry foreign DNA into a cell and replicate there ...
File
File

ChIP-on-chip - Wikipedia, the free encyclopedia
ChIP-on-chip - Wikipedia, the free encyclopedia

Unit 4 Review KEY File
Unit 4 Review KEY File

... tRNA UAC CCU AAG ...
Presentations:Questions
Presentations:Questions

... Most individuals with Klinefelter's syndrome are sterile and unable to reproduce. However, a few are able to have children. Briefly describe how this may be possible. Are these individuals male, female or hermaphroditic? ...
Chromosome Mapping by Recombination Genes on the same
Chromosome Mapping by Recombination Genes on the same

... progeny include 442 A/a.B/b, 458 a/a.b/b, 46 A/a.b/b, and 54 a/a.B/b. Explain these results. A: If the genes were unlinked, they should assort independently and the four progeny classes should be present in roughly equal proportions. This is clearly not the case. The A/a.B/b and a/a.b/b classes (the ...
2012
2012

... The linking number (Lk) of a closed-circular DNA molecule can be changed only by breaking one or both strands. ...
DNA and RNA - davis.k12.ut.us
DNA and RNA - davis.k12.ut.us

... you now have exposed nitrogen bases. Attach six mRNA nucleotides to your original DNA strand. Remember T (thymine) is replaced by U (uracil) when making RNA. Because mRNA is single stranded, it is only formed on one half of your DNA. Remove your mRNA strand from the DNA strand and put your DNA stran ...
Chapter 12
Chapter 12

... DNA fragments then need to be placed into part of the recipient cell’s genetic material ...
Key Idea 2 - Valhalla High School
Key Idea 2 - Valhalla High School

... This code is contained in __DNA__ molecules. The DNA molecules must be accurately replicated before being passed on. Once the coded information is passed on, it is used by a cell to make _proteins_____. The proteins that are made become cell parts and carry out most functions of the cell. Throughout ...
week7_DNA
week7_DNA

... 4. Nucleotides also serve as building blocks for nucleic acids ...
Genetics Quiz Study Guide
Genetics Quiz Study Guide

... Amino Acid. An organic molecule made of C, H, O, and N that serves as a building block for proteins and other molecules in living organisms. Chromosome. An organized structure of DNA and protein found in the nucleus of a cell. Chromosomes store genetic information for the cell. Co-dominant. Conditio ...
DNA- The Genetic Material
DNA- The Genetic Material

... switch. The genes that are turned on in a muscle cell are different than the genes that are turned on in a nerve cell. •Gene expression is what makes cells different in a multicellular organism ...
Genetics 101 - hrsbstaff.ednet.ns.ca
Genetics 101 - hrsbstaff.ednet.ns.ca

... to make a protein. Any changes to those instructions can alter the gene's meaning and change the protein that is made, or how or when a cell makes that protein. There are many different ways to alter a gene, just as there are many different ways to introduce typos into a sentence. In the following e ...
DNA Replication and DNA Repair Study Guide Focus on the
DNA Replication and DNA Repair Study Guide Focus on the

... i. WƌŽĐĞĞĚƐŝŶϱ͛ƚŽϯ͛ĚŝƌĞĐƚŝŽŶ;ŽŶϯ͛ƚŽϱ͛ƐƚƌĂŶĚͿ ii. Very fragmented 5. Role of helicases, topoisomerases,and single stranded binding proteins a. Helicases i. Unwind DNA ii. Require ATP 1. Hydrolyzed in order to function iii. Supercoiling-increased or decreased torsional strain put on molecule ...
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DNA supercoil



DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand. Supercoiling is important in a number of biological processes, such as compacting DNA. Additionally, certain enzymes such as topoisomerases are able to change DNA topology to facilitate functions such as DNA replication or transcription. Mathematical expressions are used to describe supercoiling by comparing different coiled states to relaxed B-form DNA.As a general rule, the DNA of most organisms is negatively supercoiled.
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