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protein synthesis
protein synthesis

Presentation
Presentation

... 1. Amino acids bond together to make proteins. 2. Proteins differ due to the number, kind, sequence and arrangement of amino acids. 3. Amino acids are attached to one another by peptide bonds to form polypeptide chains. 4. The 3D form of the protein determines ...
Transformation Pre-Lab
Transformation Pre-Lab

DNA replication - Understanding Evolution
DNA replication - Understanding Evolution

... Students will understand that 1) molecular mechanisms that preserve the fidelity of the genetic sequence have been favored by natural selection, 2) some entities, such as HIV, lack some of these mechanisms and so have a higher rate of mutation and evolution, and 3) many challenges posed to medical s ...
Section 3 - DNA Sequencing
Section 3 - DNA Sequencing

... cells of the organism. • ESTs are produced by purifying mRNA from cells and then using an enzyme called reverse transcriptase to convert these to copy DNA (cDNA). The DNA is then cloned in bacteria and sequenced. • The sequence obtained is usually only short (c. 700 base pairs) and may not be very a ...
rsc prize and award lecture
rsc prize and award lecture

... The information for synthesizing the molecules that allow organisms to survive and replicate is encoded in genomic DNA. In the cell, DNA is copied to messenger RNA, and triplet codons (64) in the messenger RNA are decoded - in the process of translation - to synthesize polymers of the natural 20 ami ...
DNA Recombination
DNA Recombination

... • DNA elements capable of moving ("transposing") around the genome • Discovered by Barbara McClintock, largely from cytogenetic studies in maize, but since found in most organisms • She was studying "variegation" or sectoring in leaves and seeds • She liked to call them "controlling elements“ becaus ...
Biotechnology and Genomics
Biotechnology and Genomics

... between 74% and 93% of the genome is transcribed into RNA but not all translated into proteins Therefore, the “junk” (nontranslated RNA) may code for regulatory gene expression necessary for proper cellular events. ...
Team Publications
Team Publications

... pathogenic mutations in patients with a family history of breast and ovarian cancer. These subtle changes frequently remain of unknown clinical significance because of the lack of genetic information that may help establish a direct correlation with cancer predisposition. Therefore, alternative ways ...
Human Mitochondrial DNA
Human Mitochondrial DNA

... The cells are concentrated into a pellet through the use of a centrifuge, and their membranes are made porous so that the rDNA has a route to enter the cell. The rDNA is added to the cell culture and some of the rDNA plasmids are absorbed, but to increase their absorption numbers the culture undergo ...
genes - Brookwood High School
genes - Brookwood High School

... a. once DNA is cut has to be sorted b. done according to size ...
Wiki - DNA Fingerprinting, Individual Identification and Ancestry
Wiki - DNA Fingerprinting, Individual Identification and Ancestry

... A typical genetic fingerprint, which looks on average at ten different microsatellites, does not reveal anything about your personality, your mental capabilities, your ethnicity or possible predispositions to disease. However, exhaustive studies on human populations from all over the world have show ...
Heredity – the passing of traits from parents to offspring
Heredity – the passing of traits from parents to offspring

Study Guide - Issaquah Connect
Study Guide - Issaquah Connect

... Which type of enzyme destroys the ability of the transforming principle to function? ...
STAAR Review 4
STAAR Review 4

... 11. Color blindness is a sex-linked recessive trait. A mother with normal color vision and a color blind father have a color blind daughter. Which of the following statements is correct? a. All of their daughters will be color blind. b. The mother is a carrier of the color blindness gene. c. All of ...
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by

Clicker Review-DNAProtein Syn Mutation
Clicker Review-DNAProtein Syn Mutation

... not double stranded Contains ribose and not deoxyribose Contains thymine and not uracil 1 and 2 are correct All are correct ...
Recombinant DNA Technology
Recombinant DNA Technology

... DNA fragments with complementary sticky ends can associate to form new DNA combinations. ...
Recombinant DNA Technology:
Recombinant DNA Technology:

... 2. Cut the human DNA and bacterial plasmids with the restriction enzyme. If you cut a plasmid DNA and human DNA with the same restriction enzyme, all the DNA fragments will have the same sticky ends. Some restriction enzymes, for example, Sma I, cut both DNA strands in the middle of the recognition ...
More Exam Practice - Iowa State University
More Exam Practice - Iowa State University

... tRNA base-pairs with start codon AUG, and then the large ribosomal subunit binds b. Elongation- the mRNA is pulled through the ribosome so a new codon is exposed in the A site and a charged tRNA docks in the A site. The mRNA will be pulled through again, which will make the first bound tRNA in the P ...
BASIC DNA
BASIC DNA

... – Regions of DNA which differ from person to person • Locus (plural = loci) – Site or location on a chromosome • Allele – Different variants which can exist at a locus • DNA Profile – The combination of alleles for an individual ...
DNA repair DNA as genetic information
DNA repair DNA as genetic information

... DNA as genetic information • DNA is more stable than RNA and double‐stranded making it a  perfect molecule for storage of information • Cellular repair mechanisms prevent accumulation of unwanted mutations by repairing 999/1000 mutations • DNA repair is dependent on double‐stranded DNA • RNA and pro ...
Key Area 2 – Pupil Booklet
Key Area 2 – Pupil Booklet

... We inherit our 46 chromosomes from our parents during fertilisation of the egg by the sperm. ...
in non sex cells
in non sex cells

Review 16-18
Review 16-18

...  Show a Punnett square cross of the P generation and the F1 generation (to show the expected F2 results)  Use the Chi-square test to determine your chi-square value of the observed vs. expected ratios.  How many degrees of freedom is there in this analysis? ...
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DNA supercoil



DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand. Supercoiling is important in a number of biological processes, such as compacting DNA. Additionally, certain enzymes such as topoisomerases are able to change DNA topology to facilitate functions such as DNA replication or transcription. Mathematical expressions are used to describe supercoiling by comparing different coiled states to relaxed B-form DNA.As a general rule, the DNA of most organisms is negatively supercoiled.
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