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Analysis of flower pigmentation mutants generated by random
Analysis of flower pigmentation mutants generated by random

... containing the dfrC gene (Gerats et al., 1990). To isolate mutants in which various steps in plant development were altered we conducted a self-pollination program of W138 plants. This yielded a collection of mutants with alterations in growth characteristics, developmental pattern formation, leaf p ...
Caenorhabditis elegans chromosome arms are anchored to the
Caenorhabditis elegans chromosome arms are anchored to the

... found to be associated with large domains up to several megabases in length, which cover about 40% of the genome in mouse and human cells [6,7]. In flies, however, the size and the coverage of lamin-associated regions were not determined precisely because the cDNA microarrays used for detection cont ...
Identifying 3D expression domains by graph clustering
Identifying 3D expression domains by graph clustering

... These expression levels help identify the state of the chromatin, as ‘closed’ chromatin will result  in lower expression levels compared to ‘open’ chromatin.   Before the publication of the TRIP method this generally required low throughput analyses as  reporters could only target specific genomic l ...
poster_CSHL_2007
poster_CSHL_2007

... FIRE (for Finding Informative Regulatory Elements) is a highly sensitive approach for motif discovery from expression data, based on mutual information. It has the following characteristics: ...
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))

... JUN is the most important component of AP-1 transcription factors, and its transcriptional activity is possibly attenuated by JUNB or JUND. It has been well accepted that JUN regulates cell proliferation, apoptosis and transformation. JUN promotes cell cycle transition from G1 phase to S phase by up ...
Allele, phenotype and disease data at Mouse Genome Informatics
Allele, phenotype and disease data at Mouse Genome Informatics

... phenotype data. For example, the Spns2tm1b(KOMP)Wtsi allele, homozygous 2 genotype is annotated with ‘decreased B cell number.’ Clicking on this term will open the MP browser, with links provided to retrieve all genotypes carrying any mutation annotated to this term or any subclass of this term. MP ...
Short Tandem Repeat Polymorphism and Cancer Risk: Influence of
Short Tandem Repeat Polymorphism and Cancer Risk: Influence of

... CA did not overlap with other bases. For the long allele, the count began at the same position as the short allele but ended at the CA repeat that overlapped with other bases. The second method used to determine the CA polymorphism was DNA sizing analysis utilizing the MicroGene Blaster automated se ...
B M B 400 Part Four
B M B 400 Part Four

File
File

... Nutrigenomics • Interaction between nutrients and genotype Variants can determine individual response to dietary factors…propensity to develop disease ...
Genetic Issues for Perinatal Nurses, 3 rd Edition
Genetic Issues for Perinatal Nurses, 3 rd Edition

... • DNA provides the codes for proteins. It is a double helix made of two strands held together with chemical bonds. • DNA replicates by undoing the bonds and creating a complementary strand. • As the strands separate, one serves as a template for messenger RNA (mRNA), the structure that carries infor ...
Export To Word
Export To Word

... fever. The male mosquitoes were modified so that when they reproduce, their offspring die before they can transmit the disease. The article contains a data table that shows a drastic reduction in the number of dengue cases in places where GM mosquitoes were used in addition to conventional control m ...
Ernest Just - CPO Science
Ernest Just - CPO Science

... In a monastery setting, one would think that Mendel would be secluded from the outside world. However, monasteries were centers of learning. The monastery suited Mendel well. It was here that he conducted his famous pea experiments. Mendel’s approach to explaining his results was unique. He used mat ...
FEBS Letters
FEBS Letters

... In addition to hoxH, the 5.0 kb segment contained upstream of hoxH the hydrogenase genes h o x Y (coding for the smaller subunit o f the hydrogenase dimer, sequence identity to the A. variabilis gene product 61% on an amino acid basis) and hoxU (coding for the smaller subunit of the diaphorase part, ...
Radiation Hybrid Mapping: A Somatic Cell Genetic Method for
Radiation Hybrid Mapping: A Somatic Cell Genetic Method for

... DNA (5). However, in practice, the paucity of useful rare-cuRer enzymes and the nonrandom distribution of rare-cutter sites in human genomic DNA make it difficult to order DNA sequences more than a few hundred kilobase pairs (kb) apart with this technique alone. Thus, obtaining long stretches of con ...
Review Article Viral Bacterial Artificial - diss.fu
Review Article Viral Bacterial Artificial - diss.fu

... genomic cDNA can be purified by gel electrophoresis and subsequently cloned into a mini-F vector by a standard ligation reaction. If synthesis of a full-length cDNA is not possible due to the size of the virus genome, fragments of the genome can be transcribed into cDNA and subsequently combined by ...
Updated ISSR and agarose gel protocol
Updated ISSR and agarose gel protocol

... 2. Heat to boiling in microwave. I recommend reducing the microwave power to 50% to limit the loss of your gel from boilover. Watch the flask as it is heating and pause the microwave if the product nears the lip of the flask. Remove the flask from the microwave and allow it to cool until you can tou ...
Protein A gene expression is regulated by DNA supercoiling which
Protein A gene expression is regulated by DNA supercoiling which

... As the expression of the protein A gene is dramatically repressed by high salt concentrations (1 M NaCl) and as high osmolarity alters the degree of plasmid DNA supercoiling, we looked at the effect of changing the degree of DNA supercoiling on protein A gene expression. We first determined the conc ...
Gene7-05
Gene7-05

... 1. Genetic information carried by DNA is expressed in two stages: transcription of DNA into mRNA; and translation of the mRNA into protein. 2. The adaptor that interprets the meaning of a codon is transfer RNA, which has a compact L-shaped tertiary structure 3. The ribosome provides the apparatus th ...
Genomic patterns of species diversity and divergence in Eucalyptus
Genomic patterns of species diversity and divergence in Eucalyptus

... This program uses a Bayesian method to identify markers with FST coefficients significantly different from the distribution of values expected under neutral theory (Foll & Gaggiotti, 2008). To avoid biasing the distribution of FST towards zero, only DArT markers scored as “1” in ≥2% and ≤98% of indi ...
Guidelines for Human Gene Nomenclature (1997)
Guidelines for Human Gene Nomenclature (1997)

... no trivial task because many of these genes share structural elements or functional attributes with each other. Added to this problem is the historical pattern of embedding in the names of the genes something about their function, relationship to other genes, expression patterns, chromosome location ...
Gene as the unit of genetic material - E
Gene as the unit of genetic material - E

... The part of the cell which occurs between the plasma membrane and nuclear envelope is known as the cytoplasm. It forms most essential part of the cell because it is seat of all biosynthetic and bio energetic functions. Most of the phenotypic characters are controlled by the genes present in the chro ...
Hd6, a rice quantitative trait locus involved in photoperiod
Hd6, a rice quantitative trait locus involved in photoperiod

... series of genes and show continuous variation in progeny. Many efforts have been made to map such genes, known as quantitative trait loci (QTLs), because of their biological and agronomic importance. The development of a high-density linkage map based on DNA markers made it possible to map QTLs with ...
Maternal plasma folate during pregnancy impacts differential DNA
Maternal plasma folate during pregnancy impacts differential DNA

Real time PCR based determination of gene copy numbers in
Real time PCR based determination of gene copy numbers in

... requires large amounts of genomic DNA. In addition, restriction site loss during ...
Trawling DNA Databases For Partial Matches: What Is The FBI
Trawling DNA Databases For Partial Matches: What Is The FBI

... DNA evidence is often presented as the “gold standard” for forensic science. But this was not always the case. For years, eminent scientists complained that the estimates of the tiny frequencies of DNA types were unfounded. It took scores of research papers, dozens of judicial opinions, and two comm ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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