Prevention of DNA Rereplication Through a Meiotic Recombination
... and Hochwagen 2013) and to unprogrammed DNA damage (Weber and Byers 1992; CartagenaLirola et al. 2008), their absence in the recombination checkpoint can be explained by the existence of meiosis-specific proteins that operate specifically in the context of recombination intermediate structures (H ...
... and Hochwagen 2013) and to unprogrammed DNA damage (Weber and Byers 1992; CartagenaLirola et al. 2008), their absence in the recombination checkpoint can be explained by the existence of meiosis-specific proteins that operate specifically in the context of recombination intermediate structures (H ...
Mitochondrial DNA disease - Human Molecular Genetics
... human embryos show equivalent levels of carryover (unpublished data), providing further evidence that the risks of offspring developing disease are likely to be minimal. Unlike pronuclear transfer, the chromosomes of the metaphase II oocyte are not enclosed within a nuclear membrane. Instead, they a ...
... human embryos show equivalent levels of carryover (unpublished data), providing further evidence that the risks of offspring developing disease are likely to be minimal. Unlike pronuclear transfer, the chromosomes of the metaphase II oocyte are not enclosed within a nuclear membrane. Instead, they a ...
Developmental Validation of the Quantifiler Real-Time
... 2000. Each sample was then quantified by entering its background-subtracted numerical fluorescence value into the regression formula and solving for DNA concentration. Slot blot hybridization DNA quantification assays were perR formed using the QuantiBlot Human DNA Quantitation Kit (Applied Biosyst ...
... 2000. Each sample was then quantified by entering its background-subtracted numerical fluorescence value into the regression formula and solving for DNA concentration. Slot blot hybridization DNA quantification assays were perR formed using the QuantiBlot Human DNA Quantitation Kit (Applied Biosyst ...
The Ethics of Reproductive Cloning
... nuclear genomes of two individuals are not combined in the same way; genetic recombination during this process occurs in a manner that does not result in a genetically unique individual. This technical and biological difference makes reproductive cloning significantly different than assisted reprodu ...
... nuclear genomes of two individuals are not combined in the same way; genetic recombination during this process occurs in a manner that does not result in a genetically unique individual. This technical and biological difference makes reproductive cloning significantly different than assisted reprodu ...
Horizontal transfer generates genetic variation in an asexual
... coverage for the 612 type 2 SNPs in LS regions, 25 was the average depth for the 261 type 2 SNPs in the core genome, and 28 was the average depth for the 3031 type 1 SNPs in the whole genome. In sum, the type 2 SNPs in the core genome were dispersed with low depths of coverage in sequence contexts ...
... coverage for the 612 type 2 SNPs in LS regions, 25 was the average depth for the 261 type 2 SNPs in the core genome, and 28 was the average depth for the 3031 type 1 SNPs in the whole genome. In sum, the type 2 SNPs in the core genome were dispersed with low depths of coverage in sequence contexts ...
Catellibacterium aquatile sp. nov., isolated from fresh water, and
... (Boldareva et al., 2008). Their wide distribution and metabolic diversity (such as heterotrophic, phototrophic and chemically autotrophic metabolism) suggest that members of this clade may play important roles in various ecosystems, especially aquatic environments. In a survey of the bacterial diver ...
... (Boldareva et al., 2008). Their wide distribution and metabolic diversity (such as heterotrophic, phototrophic and chemically autotrophic metabolism) suggest that members of this clade may play important roles in various ecosystems, especially aquatic environments. In a survey of the bacterial diver ...
Full Text - American Diabetes Association
... morphogenetic protein (BMP)-signaling pathway. The approach allows us to generate testable hypotheses from GWAS candidates falling in promoter regions and has the potential to help understand the functional impact of genetic variants in DN and other complex genetic diseases. DN is the leading cause ...
... morphogenetic protein (BMP)-signaling pathway. The approach allows us to generate testable hypotheses from GWAS candidates falling in promoter regions and has the potential to help understand the functional impact of genetic variants in DN and other complex genetic diseases. DN is the leading cause ...
Analysis of Cross Sequence Similarities for Multiple - PolyU
... engineering, forensics and anthropology. We can see that the size of the databases storing DNA, RNA and amino-acid sequences is increasing exponentially (Matsumoto et al., 2000). As an example, the lengths of the 24 chromosomes in human are found to have 50 to 250 million base pairs (Human Genome Pr ...
... engineering, forensics and anthropology. We can see that the size of the databases storing DNA, RNA and amino-acid sequences is increasing exponentially (Matsumoto et al., 2000). As an example, the lengths of the 24 chromosomes in human are found to have 50 to 250 million base pairs (Human Genome Pr ...
Chapter 8
... Learning Objectives 8-1 Define genetics, genome, chromosome, gene, genetic code, genotype, phenotype, and genomics. 8-2 Describe how DNA serves as genetic information. 8-3 Describe the process of DNA replication. 8-4 Describe protein synthesis, including transcription, RNA processing, and translatio ...
... Learning Objectives 8-1 Define genetics, genome, chromosome, gene, genetic code, genotype, phenotype, and genomics. 8-2 Describe how DNA serves as genetic information. 8-3 Describe the process of DNA replication. 8-4 Describe protein synthesis, including transcription, RNA processing, and translatio ...
Identification and characterization of the Plasmodium vivax
... compared to P. falciparum due to its tropism for reticulocytes, which account for less than 1% of the total circulating red blood cell (RBC) count and, therefore, makes it difficult to maintain an in vitro culture of this species [4]. However, the release of the complete genome sequences of P. falci ...
... compared to P. falciparum due to its tropism for reticulocytes, which account for less than 1% of the total circulating red blood cell (RBC) count and, therefore, makes it difficult to maintain an in vitro culture of this species [4]. However, the release of the complete genome sequences of P. falci ...
Potato chromosomes IX and XI carry genes for resistance to potato
... scorable PCR marker linked to Gm (Fig. 2, lane 6). Mapping of the PVM resistance gene Rm The screening of the parental DNA of the ‘‘Rm’’ population with 56 ISSR and 185 RAPD primers resulted in detection of 121 (23%) and 485 (32%) polymorphic DNA fragments. However, only one 1,079 bp ISSR product, a ...
... scorable PCR marker linked to Gm (Fig. 2, lane 6). Mapping of the PVM resistance gene Rm The screening of the parental DNA of the ‘‘Rm’’ population with 56 ISSR and 185 RAPD primers resulted in detection of 121 (23%) and 485 (32%) polymorphic DNA fragments. However, only one 1,079 bp ISSR product, a ...
The DpnI/DpnII pneumococcal system, defense against foreign
... the 7 acidic carboxy terminal amino acids of SsbB (ssbB∆7 mutant).12 Neither the lack of SsbB nor the absence of its acidic tail altered chromosomal transformation of plasticity islands (Fig. 3A), suggesting that the ssDNA-binding protein neither competes with or recruits DpnA to internalized ssDNA ...
... the 7 acidic carboxy terminal amino acids of SsbB (ssbB∆7 mutant).12 Neither the lack of SsbB nor the absence of its acidic tail altered chromosomal transformation of plasticity islands (Fig. 3A), suggesting that the ssDNA-binding protein neither competes with or recruits DpnA to internalized ssDNA ...
An assessment of the risks associated with the
... Homologous recombination in section Bacterial DNA transfer and recombination systems), but can be random, being mediated by a recombination mechanism intrinsic to the plant cell. Once established in a chromosome of a plant cell, bacterial DNA sequences are chemically indistinguishable from the rest ...
... Homologous recombination in section Bacterial DNA transfer and recombination systems), but can be random, being mediated by a recombination mechanism intrinsic to the plant cell. Once established in a chromosome of a plant cell, bacterial DNA sequences are chemically indistinguishable from the rest ...
this PDF file
... When 5A7 was first isolated, it was identified as a “brown” non-photosynthetic mutant. Spectrophotometric and HPLC results have shown that 5A7 lacks detectable Chl (Fig. 3; Table 1). Collaborative work with Dr. Bernhard Grimm of Humboldt University (Berlin, Germany), has revealed that 5A7 over-accum ...
... When 5A7 was first isolated, it was identified as a “brown” non-photosynthetic mutant. Spectrophotometric and HPLC results have shown that 5A7 lacks detectable Chl (Fig. 3; Table 1). Collaborative work with Dr. Bernhard Grimm of Humboldt University (Berlin, Germany), has revealed that 5A7 over-accum ...
Paper Title (use style: paper title)
... natural selection. Thus, we can gain great deal of insight not only into how proteins and genes evolve during any time by the study of natural selection in species, but can also identify the genetic changes in species responsible for specific adaptations and mutations by identifying the patterns lef ...
... natural selection. Thus, we can gain great deal of insight not only into how proteins and genes evolve during any time by the study of natural selection in species, but can also identify the genetic changes in species responsible for specific adaptations and mutations by identifying the patterns lef ...
- California State University
... specific subsets of protein-coding genes that are functional in modern humans and that include at least one amino acid change between Denisovans and modern humans. The present study focuses primarily on single nucleotide changes (SNCs), loci at which the identity of the nucleotide at a particular lo ...
... specific subsets of protein-coding genes that are functional in modern humans and that include at least one amino acid change between Denisovans and modern humans. The present study focuses primarily on single nucleotide changes (SNCs), loci at which the identity of the nucleotide at a particular lo ...
Structural Domains and Matrix Attachment Regions
... screening after digestions with sets of carefully chosen restriction endonucleases (see Methods). This approach, however, generated a very large number of fragments, and we have chosen to reexamine only the low-copy-number regions of the maize contig under new binding conditions. Multiple overlappin ...
... screening after digestions with sets of carefully chosen restriction endonucleases (see Methods). This approach, however, generated a very large number of fragments, and we have chosen to reexamine only the low-copy-number regions of the maize contig under new binding conditions. Multiple overlappin ...
Insights into three whole-genome duplications gleaned
... lineage. Though large-scale synteny has broken down to an extent between P. caudatum and the P. aurelia species, a substantial degree of local synteny remains (Figure 2). We were able to align 5,781 P. caudatum genes with all 12 of their syntenic aurelia orthologs (when present), which includes 10, ...
... lineage. Though large-scale synteny has broken down to an extent between P. caudatum and the P. aurelia species, a substantial degree of local synteny remains (Figure 2). We were able to align 5,781 P. caudatum genes with all 12 of their syntenic aurelia orthologs (when present), which includes 10, ...
network models for genetic testing
... Genomics is a relatively new scientific field that studies how genes are related to human health and disease [5]. The core technology that transformed genetic research, helped understanding genetic factors and led to prevention of birth defects and disabilities is DNA sequencing. However, the contin ...
... Genomics is a relatively new scientific field that studies how genes are related to human health and disease [5]. The core technology that transformed genetic research, helped understanding genetic factors and led to prevention of birth defects and disabilities is DNA sequencing. However, the contin ...
Mitonuclear linkage disequilibrium in human populations
... mitochondrial alleles (haplogroups), we calculated multi-allelic LD using the following measures as defined by Zhao et al. [76]: D0 , r 2, D*, x 2df and x 20 . We accounted for differences in ploidy between autosomes, sex chromosomes and the mitochondrial genome by randomly sampling one allele per i ...
... mitochondrial alleles (haplogroups), we calculated multi-allelic LD using the following measures as defined by Zhao et al. [76]: D0 , r 2, D*, x 2df and x 20 . We accounted for differences in ploidy between autosomes, sex chromosomes and the mitochondrial genome by randomly sampling one allele per i ...
SERK and APOSTART. Candidate Genes for
... both meiotic reduction and egg fertilization. The essential feature of apomixis is that an embryo is formed autonomously by parthenogenesis from an unreduced egg of an embryo sac generated through apomeiosis. If apomixis were well understood and harnessed, it could be exploited to indefinitely propa ...
... both meiotic reduction and egg fertilization. The essential feature of apomixis is that an embryo is formed autonomously by parthenogenesis from an unreduced egg of an embryo sac generated through apomeiosis. If apomixis were well understood and harnessed, it could be exploited to indefinitely propa ...
Marker Saturation and Construction of a High
... appropriate temperature, 90 s amplification reactions at 72 oC and 5 min extension at 72 ...
... appropriate temperature, 90 s amplification reactions at 72 oC and 5 min extension at 72 ...
Epigenetic memory in mammals
... transfer epigenetic information from one generation to the next. Epigenetic information uses patterns of inheritance, which are not determined by DNA sequence alone and may result in an epigenetic memory, which like genetic memory can be stably inherited and passed onto progeny through meiosis, alth ...
... transfer epigenetic information from one generation to the next. Epigenetic information uses patterns of inheritance, which are not determined by DNA sequence alone and may result in an epigenetic memory, which like genetic memory can be stably inherited and passed onto progeny through meiosis, alth ...