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Star Method for MSA and Its Parallelization
Star Method for MSA and Its Parallelization

... This research does not attempt to solve quadratic space complexity of Smith-Waterman; so memory requirement of matrixH is high. In fact, it can limits parallel pair executions such that at one time there is only one pair similarity score is computed. For example, alignment of two mutations of rhodop ...
- Genetics
- Genetics

... and the advantages and disadvantages in the two sexes conflict, but are more often found at autosomal loci when predation is weak (Gordon et al. 2012), suggesting that SA selection has affected the establishment of polymorphisms. However, no evidence definitively connects SA alleles to the evolution o ...
characterizing the genetic bases of autosomal recessive disorders
characterizing the genetic bases of autosomal recessive disorders

... and their families. Elucidating the genetic bases of such disorders is essential to improve their clinical outcome and for implementing effective prevention programs. In this dissertation, the genetic bases of seven autosomal recessive disorders in consanguineous families were investigated using hom ...
Effective transfer of chromosomes carrying leaf rust resistance
Effective transfer of chromosomes carrying leaf rust resistance

... located on chromosome 5B(5BL), and the Ph2 gene on chromosome 3DS and 3AS (Mello-Sampayo 1971). The Chinese Spring ph1b (CSph1b) mutant genotype (Sears 1977), which lacks the Ph1 locus, has been successfully used for the introgression of alien genetic material into the wheat genome by the induction ...
Mutualism and asexual reproduction influence recognition genes in
Mutualism and asexual reproduction influence recognition genes in

... the fungus, has influenced the evolution of the genes determining sexual recognition in the fungal partner. Two specific questions were addressed: (i) How does the pattern and extent of polymorphism at a mat locus compare to those in other regions of the genome? (ii) Which evolutionary forces most l ...
Slides
Slides

... Chromosomes are made up of a single continuous DNA molecule can’t be straight-- would be many times length of the cell Chromatin: ordered aggregate of DNA and proteins visible in the cell cycle ...
Nucleolar caspase-2: Protecting us from DNA damage
Nucleolar caspase-2: Protecting us from DNA damage

... several cell lines. Thus, NPM1 and the NPM1–PIDD interaction are critical for damage-induced nucleolar PIDDosome signaling. Interestingly, NPM1 itself is known to have roles in apoptosis; in particular, NPM1 is the main cellular reservoir of p14ARF (Box et al., 2016). Further, NPM1 translocates to d ...
Genetics and genomics for nurses working in general practice
Genetics and genomics for nurses working in general practice

... www.geneticseducation.nhs.uk © 2012 NHS National Genetics Education and Development Centre © 2014 NHS National Genetics and Genomics Education Centre ...
Epigenetic Mediation of Environmental Influences in Major Psychotic
Epigenetic Mediation of Environmental Influences in Major Psychotic

... changes. It appears that the epigenome is particularly susceptible to disruption during a number of key developmental periods, especially during prenatal growth when rapid cell replication is occurring and the standard epigenetic signals driving development are being established.16 Environmental med ...
fulltext
fulltext

... Tardigrades are known for being resistant to extreme conditions, including tolerance to ionising and UV radiation in both the hydrated and the dehydrated state. It is known that these factors may cause damage to DNA. It has recently been shown that single and double DNA strand breaks occur when tard ...
Biotechnology Timeline
Biotechnology Timeline

... Frederick Sanger. 3D model of insulin ...
KARNATAKA COMMON ENTRANCE TEST – MAY, 2016 BIOLOGY
KARNATAKA COMMON ENTRANCE TEST – MAY, 2016 BIOLOGY

... Disclaimer: These solutions are provided by the academic team of BASE. These solutions may be different from those to be provided by the Karnataka Examinations Authority (KEA) due to difference in assumptions taken in support of the solutions. In such cases solution provided by KEA will be deemed as ...
DNA methylation controls histone H3 lysine 9 methylation
DNA methylation controls histone H3 lysine 9 methylation

... 2002). The interactions between DNA methylation, histone modi®cations and chromatin structure have mainly been studied at the molecular level for speci®c DNA sequences. Integrated genetic, molecular and cytological approaches can provide new insights into chromatin remodeling. For example, genome-wi ...
Plants` Epigenetic Secrets
Plants` Epigenetic Secrets

... There are three different types of DNA methylation in plants: CG, CHH (where H is any base except G), and CHG. In Arabidopsis, CG methylation is found on some genes, but primarily on repeat sequences that make up transposons, as well as other repeat sequences in the genome. CHH methylation is found ...
Molecular Classification of Infectious Laryngotracheitis Virus from
Molecular Classification of Infectious Laryngotracheitis Virus from

... (accession no. EU104908) were used as a prototype for a primer design to cover the region of 450 basepairs (bp) by Primer3 software. The simulation sequences of CEO vaccine virus (accession no. EU104900) and TCO vaccine virus (accession no. EU104908) from PCR reaction were selected for restriction e ...
The Use of Cytochrome B Sequence Variation in Estimation of
The Use of Cytochrome B Sequence Variation in Estimation of

... DNA was isolated from tissue samples representing nine Vireo speciescommonly found in North America, for two speciesof the confamilial genera Vireolanius and Cyclarhis and the Blackbilled Magpie (Pica pica). The Black-billed Mag- ...
Genomic Screening for Artificial Selection during Domestication and
Genomic Screening for Artificial Selection during Domestication and

... search for selection using patterns of DNA sequence diversity involves detecting inconsistency in the pattern of genetic polymorphism compared with the expectation of the neutral equilibrium model. There are three types of natural selection: positive selection (sometimes referred to as directional s ...
TEL Gene Is Involved in Myelodysplastic Syndromes
TEL Gene Is Involved in Myelodysplastic Syndromes

... A 1,241-bp TEL cDNA was obtained containing the complete coding sequence. The sequence of this cDNA was identical to the published one.I3 The cDNA was used to screen a chromosome 12 cosmid library. Ten cosmids were obtained and characterized by Southern hybridization with restriction fragments of th ...
Document
Document

... RNA-Seq Lab v5 | Radhika S. Khetani ...
Intelligent Icons: Integrating Lite-Weight Data Mining
Intelligent Icons: Integrating Lite-Weight Data Mining

... The three files in the example are ASCII text files, each of which contains approximately 16,000 base pairs of mitochondrial DNA. Here we used string edit distance as suggested in [15] to measure the distance between file names, and Euclidean distance to measure the distance between the file icons ( ...
Document
Document

Cloning and Genetic Analysis of Six Pyrroloquinoline
Cloning and Genetic Analysis of Six Pyrroloquinoline

... Duine, 1988). PQQ biosynthesis mutants were first reported in A. calcoaceticus as being unable to oxidize glucose to gluconate (Goosen et al., 1987). These mutants were used for cloning four genes involved in PQQ biosynthesis. DNA sequence analysis failed to give clues to the nature of putative bios ...
Recruitment of Drosophila Polycomb Group proteins to
Recruitment of Drosophila Polycomb Group proteins to

... mutation in ph (ph410) did not have any effect (Fig. 2b). Ab-Fab has previously been shown to mediate trxG-dependent maintenance of active chromatin states following an embryonic pulse of transcriptional activation2. Interestingly however, we found that this maintenance can only be observed when Ab- ...
Nature Genetics: doi:10.1038/ng.3791
Nature Genetics: doi:10.1038/ng.3791

Capstone project 2015 in pdf format
Capstone project 2015 in pdf format

... We recently demonstrated resilience of dinoflagellates to DNA damage agents. The present project aims to isolate and characterize dinoflagellate mutants with different genome sizes. The project will involve cell biological and molecular techniques in the generation and monitoring of dinoflagellate l ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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